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Träfflista för sökning "WFRF:(Björk Anne) srt2:(2010-2014)"

Sökning: WFRF:(Björk Anne) > (2010-2014)

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11.
  • Knutsson, Eva Smith, et al. (författare)
  • Genital Chronic Graft-versus-Host Disease in Females: A Cross-Sectional Study
  • 2014
  • Ingår i: Biology of Blood and Marrow Transplantation. - : Elsevier BV. - 1083-8791 .- 1523-6536. ; 20:6, s. 806-811
  • Tidskriftsartikel (refereegranskat)abstract
    • Using the National Institutes of Health (NIH) consensus criteria for chronic graft-versus-host disease (cGVHD), we assessed the prevalence, symptoms, and clinical signs of female genital cGVHD in a cross-sectional population-based study. Forty-two women were evaluated at a median of 80 months (range, 13 to 148 months) after undergoing hematopoietic stem cell transplantation (HSCT). Medical history, ongoing medications, and genital signs and symptoms were recorded. Gynecologic examination for the diagnosis and clinical scoring of genital cGVHD was combined with clinical scoring of extragenital cGVHD for the estimation of each patient’s global cGVHD score. Biopsy specimens from the genital mucosa were obtained from 38 patients. Genital cGVHD was diagnosed in 22 of 42 patients (52%). Its presence was associated with systemic corticoid steroid treatment of extragenital cGVHD (P .001), older age (P .07), and HSCT from a sibling donor (P .002). Five patients had isolated genital cGVHD. Dryness, pain, smarting pain (P < .05 for all), and dyspareunia (P .001) were observed more frequently in the women with genital cGVHD. Twelve patients had advanced genital cGVHD (clinical score 3), which was the main factor explaining the high rate (15 of 42) of severe global cGVHD. The rate of genital cGVHD was similar (P .37) in patients with a follow-up of 80 months (10 of 22) and those with a follow-up of <80 months (12 of 20). We found no convincing relationship between clinical diagnosis and histopathological assessment of mucosal biopsy specimens. In our group of women with a long follow-up after HSCT, genital cGVHD was common and in many cases incorrectly diagnosed. Genital cGVHD causes genital symptoms and affects sexual life, and may present without any other cGVHD, warranting early and continuous gynecologic surveillance in all women after HSCT.
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12.
  • Kästel, Anne, et al. (författare)
  • Parents’ views on information in childhood cancer care
  • 2011
  • Ingår i: European Journal of Oncology Nursing. - : Elsevier. - 1462-3889 .- 1532-2122. ; 15:4, s. 290-295
  • Tidskriftsartikel (refereegranskat)abstract
    • PurposeThe aim of the study is to highlight parents’ views on information in childhood cancer care.MethodA qualitative design, appropriate to gain a holistic view, has been chosen. Eight families with children diagnosed with cancer, of various ages and gender and from various backgrounds, participated in five interviews each during the first year of the child’s illness.ResultsIf the parents’ needs were fulfilled, they were better equipped to handle the illness of their child, which is totally dependant on how the matter of information is dealt with. Information is a complex and demanding issue for the persons involved and the families’ views were divergent in this area. Sometimes they seemed to obtain the information successfully and sometimes there were great problems in this respect. Therefore their preferences must be considered.ConclusionThere has to be an improvement from the aspects of what, when and how information is provided. The major findings of this study indicate that the families need better support and more distinct instructions to be able to cope with the situation.
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