| 11. |
- Huss, Fredrik, 1971-, et al.
(författare)
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Brännskador
- 2010. - 7
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Ingår i: Akut Pediatrik. - Stockholm : Liber. - 9789147094028 ; , s. 138-146
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 12. |
- Iredahl, Fredrik, et al.
(författare)
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The Microvascular Response to Transdermal Iontophoresis of Insulin is Mediated by Nitric Oxide
- 2013
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Ingår i: Microcirculation. - : WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA. - 1073-9688 .- 1549-8719. ; 20:8, s. 717-723
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveInsulin has direct effects on blood flow in various tissues, most likely due to endothelial NO production. We investigated whether insulin delivered to the skin by iontophoresis increases microvascular perfusion and whether this effect is partly or completely mediated by the release of NO. MethodsIn healthy subjects, regular insulin and monomeric insulin were delivered to the skin by cathodal iontophoresis. The skin was pretreated either with L-NAME or control solution (PBS) using anodal iontophoresis. Microvascular responses were measured using laser Doppler flowmetry. ResultsA dose-dependent increase in perfusion was observed during iontophoresis of regular and monomeric insulin. The maximum perfusion was significantly elevated compared with control after PBS (regular insulin 53.6 (12.7-95.6) PU vs. 4.2 (3.4-4.8) PU, p = 0.002; monomeric insulin 32.6 (8.9-92.6) PU vs. 5.9 (3.4-56.0) PU, p = 0.03). The microvascular response to insulin was abolished after L-NAME (regular insulin: 25.6 (11.6-54.4) PU vs. control: 4.7 (2.9-11.5) PU, p = 0.15; monomeric insulin 10.9 (5.4-56.8) PU vs. control: 4.7 (2.9-11.5) PU, p = 0.22). ConclusionsThe main finding is that iontophoresis of insulin induces a dose-dependent vasodilation in the skin, which could be suppressed after pretreatment with a NO synthase inhibitor. This suggests that vasodilation in the skin after iontophoresis of insulin is mediated by the NO pathway.
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| 13. |
- Kjellman, Britt-Marie, et al.
(författare)
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Comparing ambient, air-convection, and fluid-convection heating techniques in treating hypothermic burn patients, a clinical RCT
- 2011
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Ingår i: Annals of Surgical Innovation and Research. - : BioMed Central. - 1750-1164. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Background: Hypothermia in burns is common and increases morbidity and mortality. Several methods are available to reach and maintain normal core body temperature, but have not yet been evaluated in critical care for burned patients. Our units ordinary technique for controlling body temperature (Bair Hugger®+ radiator ceiling + bed warmer + Hotline®) has many drawbacks e.g.; slow and the working environment is hampered.The aim of this study was to compare our ordinary heating technique with newly-developed methods: the Allon™2001 Thermowrap (a temperature regulating water-mattress), and Warmcloud (a temperature regulating air-mattress).Methods: Ten consecutive burned patients (andgt; 20% total burned surface area and a core temperature andlt; 36.0C) were included in this prospective, randomised, comparative study. Patients were randomly exposed to 3 heating methods. Each treatment/measuring-cycle lasted for 6 hours. Each heating method was assessed for 2 hours according to a randomised timetable. Core temperature was measured using an indwelling (bladder) thermistor. Paired t-tests were used to assess the significance of differences between the treatments within the patients. ANOVA was used to assess the differences in temperature from the first to the last measurement among all treatments. Three-way ANOVA with the Tukey HSD post hoc test and a repeated measures ANOVA was used in the same manner, but included information about patients and treatment/measuring-cycles to control for potential confounding. Data are presented as mean (SD) and (range). Probabilities of less than 0.05 were accepted as significant.Results: The mean increase, 1.4 (SD 0.6C; range 0.6-2.6C) in core temperature/treatment/measuring-cycle highly significantly favoured the Allon™2001 Thermowrap in contrast to the conventional method 0.2 (0.6)C (range -1.2 to 1.5C) and the Warmcloud 0.3 (0.4)C (range -0.4 to 0.9C). The procedures for using the Allon™2001 Thermowrap were experienced to be more comfortable and straightforward than the conventional method or the Warmcloud.Conclusions: The Allon™2001 Thermowrap was more effective than the Warmcloud or the conventional method in controlling patients temperatures. © 2011 Kjellman et al; licensee BioMed Central Ltd.
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| 14. |
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| 15. |
- Nilsson, Heléne, et al.
(författare)
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Simulation-assisted burn disaster planning
- 2013
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Ingår i: Burns. - : Elsevier. - 0305-4179 .- 1879-1409. ; 39:6, s. 1122-1130
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to evaluate the Swedish medical systems response to a mass casualty burn incident in a rural area with a focus on national coordination of burn care. Data were collected from two simulations of a mass casualty incident with burns in a rural area in the mid portion of Sweden close to the Norwegian border, based on a large inventory of emergency resources available in this area as well as regional hospitals, university hospitals and burn centres in Sweden and abroad. The simulation system Emergo Train System (R) (ETS) was used and risk for preventable death and complications were used as outcome measures: simulation I, 18.5% (n = 13) preventable deaths and 15.5% (n = 11) preventable complications; simulation II, 11.4% (n = 8) preventable deaths and 11.4% (n = 8) preventable complications. The last T1 patient was evacuated after 7 h in simulation I, compared with 5 h in simulation II. Better national coordination of burn care and more timely distribution based on the experience from the first simulation, and possibly a learning effect, led to a better patient outcome in simulation II. The experience using a system that combines both process and outcome indicators can create important results that may support disaster planning.
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| 16. |
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| 17. |
- Ramnerö, Jonas, et al.
(författare)
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Exposure Therapy : What Is It That We Are Selling?
- 2012
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Ingår i: Pragmatic Case Studies in Psychotherapy. - : National Register of Health Service Psychologists. - 1553-0124. ; 8:4, s. 296-301
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Tidskriftsartikel (refereegranskat)abstract
- This discussion is a response to Muller and Schultz’s (2012) thoughtful commentary on our case series on treating Body Dysmorphic Disorder (BDD) in this issue of the Pragmatic Case Studies in Psychotherapy. We join Muller and Schultz in their dedication to exposure treatment. We elaborate on their perceptive comments on what exposure is, and how it is presented, applied, and implemented most effectively, in the context of BDD specifically. We conclude by briefly exploring some of the complexities of the theory underlying exposure therapy.
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| 18. |
- Sveen, Josefin, et al.
(författare)
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Psychometric properties of the impact of event scale-revised in patients one year after burn injury
- 2010
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Ingår i: Journal of Burn Care and Research. - 1559-0488 .- 1559-047X. ; 31:2, s. 310-318
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Tidskriftsartikel (refereegranskat)abstract
- Burn injury can be a life-threatening and traumatic event. Despite considerable risk for psychological morbidity, few outcome measures have been evaluated. The aim of this study was to examine the psychometric properties of a Swedish version of the Impact of Event Scale-Revised (IES-R) in patients 1 year after burn injury (N = 147). A principal component analysis was performed, and the results supported the three-factor structure of the IES-R. High internal consistency and intelligible associations with concurrent psychological symptoms and known risk factors for distress after trauma indicate satisfactory psychometric properties. Thus, the study supports the use of the IES-R as a screening tool for measuring traumatic distress after burn.
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| 19. |
- Sveen, Josefin, et al.
(författare)
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Psychometric Properties of the Swedish Version of the Burn Outcomes Questionnaire for Children Aged 5 to 18 Years
- 2012
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Ingår i: JOURNAL OF BURN CARE and RESEARCH. - : Lippincott, Williams and Wilkins. - 1559-047X .- 1559-0488. ; 33:6, s. E286-E294
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Tidskriftsartikel (refereegranskat)abstract
- pediatric burn injuries are common, there is a lack of burn-specific health outcome measurements for children. The American Burn Association and the Shriners Hospitals for Children have developed the Burn Outcomes Questionnaire (BOQ), which is a parent-report questionnaire measuring the functional outcome after burn in children aged 5 to 18 years. The aim of this study was to examine the psychometric properties of the Swedish version of the BOQ, assessing feasibility, reliability, and validity aspects. Participants were parents (n = 70) of children aged 5 to 18 years who were treated at the Uppsala or Linkoping burn center between January 2000 and December 2008. For most subscales, feasibility was adequate and the internal consistency was good: Cronbachs a values were above 0.76 in all but 1 subscale, and mean interitem correlations ranged from 0.34 to 0.90. The test-retest reliability was significant in the majority of subscales. Evidence of validity was shown by associations among the BOQ subscales and between BOQ subscales and measures of burn severity, heat sensitivity, fear-avoidance beliefs, and parent reports of the childs psychological problems. In conclusion, with the exception of a few subscales, this study supports the continued evaluation of the Swedish version of BOQ as a tool to measure outcome after burn in children aged 5 to 18 years.
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| 20. |
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