| 11. |
- Henoch, Ingela, 1956, et al.
(författare)
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The impact of symptoms, coping capacity, and social support on quality of life experience over time in patients with lung cancer.
- 2007
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Ingår i: Journal of pain and symptom management. - : Elsevier BV. - 0885-3924 .- 1873-6513. ; 34:4, s. 370-9
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Tidskriftsartikel (refereegranskat)abstract
- The aims of the study were to investigate lung cancer patients' quality of life (QoL) over time in a palliative setting and to determine how QoL is influenced by symptoms, coping capacity, and social support. One hundred and five consecutive patients with incurable lung cancer were included. A comprehensive set of questionnaires was used at baseline, including the Assessment of Quality of Life at the End of Life, Cancer Dyspnea Scale, Visual Analog Scale of Dyspnea, Hospital Anxiety and Depression scale, Sense of Coherence Questionnaire, and Social Support Survey, of which the first four were used also at three, six, nine, and 12 months. Dyspnea, depression, and global QoL deteriorated over time. Performance status, anxiety, depression, components of dyspnea, pain, and the meaningfulness component of coping capacity correlated with global QoL at all, or all but one follow-up measurements. In a multivariate analysis with global QoL as the dependent variable, depression was a significant predictor at four out of five assessments, whereas coping capacity, anxiety, performance status, pain, and social support entered the model at one or two assessments. Emotional distress and coping capacity influence QoL and might be targets for intervention in palliative care.
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| 12. |
- Kåbjörn-Gustafsson, Christina, et al.
(författare)
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Cell Senescence in Myxoid/Round Cell Liposarcoma
- 2014
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Ingår i: Sarcoma. - : Hindawi Limited. - 1357-714X .- 1369-1643. ; 2014:Article ID 208786
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Tidskriftsartikel (refereegranskat)abstract
- Myxoid/round cell liposarcoma (MLS/RCLS) is the second most common liposarcoma type and characterized by the fusion oncogenes FUS-DDIT3 or EWSR1-DDIT3. Previous analysis of cell cycle regulatory proteins revealed a prominent expression of G1-cyclins, cyclin dependent kinases and their inhibitors but very few cells progressing through the G1/S boundary. Here, we extend the investigation to proteins involved in cell senescence in an immunohistochemistry based study of 17 MLS/RCLS cases. Large subpopulations of tumor cells expressed the RBL2 pocket protein and senescence associated heterochromatin 1γ and IL8 receptor β. We conclude that MLS/RCLS tissues contain major populations of senescent tumor cells and this may explain the slow growth rate of this tumor type.
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| 13. |
- Larson, Fanny, et al.
(författare)
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Key Factors for Successful General Anesthesia of Obese Adult Patients
- 2019
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Ingår i: Journal of Perianesthesia Nursing. - : Elsevier. - 1089-9472 .- 1532-8473. ; 34:5, s. 956-964
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To study nurse anesthetists' experiences of key factors for successful airway management in general anesthesia of adult obese patients.Design: The study was a qualitative observational study with a descriptive approach.Methods: Eight semistructured interviews were conducted. Data were analyzed using the critical incident technique.Findings: Five key factors for successful general anesthesia of adult obese patients were identified. These factors were preparing and planning the anesthesia, optimizing patient position, optimizing ventilation through proper preoxygenation and increasing positive end-expiratory pressure, quickly securing the airway, and working in teams.Conclusions: Knowledge of key factors that facilitate and improve the anesthesia care of obese patients is important to provide safe and quality anesthesia to this patient group as obese patients often have small margins and urgent situations can quickly arise. This knowledge enables the nurse anesthetist to be one step ahead and to be ready to take action if complications occur.
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| 14. |
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| 15. |
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| 16. |
- Wennman, Ingela, et al.
(författare)
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The clinical consequences of a pre-hospital diagnosis of stroke by the emergency medical service system. A pilot study.
- 2012
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Ingår i: Scandinavian journal of trauma, resuscitation and emergency medicine. - : Springer Science and Business Media LLC. - 1757-7241. ; 20
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Tidskriftsartikel (refereegranskat)abstract
- There is still a considerable delay between the onset of symptoms and arrival at a stroke unit for most patients with acute stroke.The aim of the study was to describe the feasibility of a pre-hospital diagnosis of stroke by an emergency medical service (EMS) nurse in terms of diagnostic accuracy and delay from dialing 112 until arrival at a stroke unit.Between September 2008 and November 2009, a subset of patients with presumed acute stroke in the pre-hospital setting were admitted by EMS staff directly to a stroke unit, bypassing the emergency department. A control group, matched for a number of background variables, was created.In all, there were 53 patients in the direct admission group, and 49 patients in the control group. The median delay from calling for an ambulance until arrival at a stroke unit was 54 minutes in the direct admission group and 289 minutes in the control group (p < 0.0001).In a comparison between the direct admission group and the control group, a final diagnosis of stroke, transient ischemic attack (TIA) or the sequelae of prior stroke was found in 85% versus 90% (NS). Among stroke patients who lived at home prior to the event, the percentage of patients that were living at home after 3 months was 71% and 62% respectively (NS).In a pilot study, the concept of a pre-hospital diagnosis of stroke by an EMS nurse was associated with relatively high diagnostic accuracy in terms of stroke-related diagnoses and a short delay to arrival at a stroke unit. These data need to be confirmed in larger studies, with a concomitant evaluation of the clinical consequences and, if possible, the level of patient satisfaction as well.
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| 17. |
- Zippert, Malin, et al.
(författare)
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Matematiska uttrycksformer och representationer
- 2011
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Ingår i: Nämnaren. - : Nationellt centrum för matematikutbildning (NCM). - 0348-2723. ; 3, s. 36-46
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- I denna artikel ger författarna exempel på hur IKT kan användas för att arbeta med både matematiska uttrycksformer och representationer. Ofta skiljer vi inte på uttrycksformer och representationer, utan de får stå för samma sak. För tydlighetens skull diskuteras de dock här var för sig. Artikeln innehåller även exempel på tillämpningar från gymnasiet.
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