| 11. |
- Joss, D. T., et al.
(författare)
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The influence of quasineutron configurations on 161Ta and nearby odd-A nuclei
- 2011
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Ingår i: AIP Conf. Proc.. - : AIP. - 9780735409835 ; , s. 43-48
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Konferensbidrag (refereegranskat)abstract
- Several strongly coupled bands in the neutron-deficient nucleus 161Ta have been identified and quasiparticle configuration assignments have been made on the basis of rotational alignments and cranked shell model calculations. The level scheme elucidated for 161Ta highlights the competition between the ν(h 9/2) and ν(i 13/2) orbitals to form the yrast spectrum. The band structures in 161Ta also provide new insights into the structural features of other heavy odd-A nuclei populated with much lower reaction cross sections in this region at the proton drip line.
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| 12. |
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| 13. |
- Palacz, M., et al.
(författare)
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Investigations of Neutron Deficient Nuclei Close to 100Sn with EUROBALL
- 2001
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Ingår i: Acta Physica Polonica. Series B: Elementary Particle Physics, Nuclear Physics, Statistical Physics, Theory of Relativity, Field Theory. - 0587-4254 .- 1509-5770. ; 32, s. 999-1003
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Tidskriftsartikel (refereegranskat)abstract
- Excited states of nuclei in the vicinity of Sn-100 have been studied using: the EUROBALL detector array. Gamma-ray lines from Sn-103 have been identified for the first time, and a level scheme of low-lying excited states of Sn-103 has been established. New constraints on energies of single particle orbitals with respect to the Sn-100 core are obtained.
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| 14. |
- Sohler, D, et al.
(författare)
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Maximally Aligned States in the Proton Drip Line Nucleus 106Sb
- 2005
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Ingår i: Nuclear Physics, Section A. - : Elsevier BV. - 0375-9474 .- 1873-1554. ; 753:3-4, s. 251-262
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Tidskriftsartikel (refereegranskat)abstract
- High-spin states in Sb-106 have been investigated in the Fe-54(Ni-58, 1α 1p1n) reaction by in-beam γ-spectroscopic methods using the EUROBALL detector array equipped with charged particle and neutron detectors. On the basis of measured γγ-coincidence relations, angular distributions, and linear polarization ratios a significantly extended level scheme has been constructed up to spin and parity I-π = (19(-)) and E-x ∼ 6.5 MeV. The experimental results are interpreted within the framework of the gdsh shell model using a realistic effective nucleon-nucleon interaction. Candidates for states with fully aligned angular momenta in the π(d(5/2), g(7/2))(1) v (d(5/2), g(7/2))(5) valence space are identified at 4338 and 5203 keV, as well as in the π(d(5/2), g(7/2))(1) V(d(5/2), g(7/2))(4)h(11/2)(1) space at 6087, 6573 and 6783 keV.
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| 15. |
- Turkington, RC, et al.
(författare)
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Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma
- 2019
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Ingår i: Gut. - : BMJ. - 1468-3288 .- 0017-5749. ; 68:11, s. 1918-1927
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Tidskriftsartikel (refereegranskat)abstract
- Current strategies to guide selection of neoadjuvant therapy in oesophageal adenocarcinoma (OAC) are inadequate. We assessed the ability of a DNA damage immune response (DDIR) assay to predict response following neoadjuvant chemotherapy in OAC.DesignTranscriptional profiling of 273 formalin-fixed paraffin-embedded prechemotherapy endoscopic OAC biopsies was performed. All patients were treated with platinum-based neoadjuvant chemotherapy and resection between 2003 and 2014 at four centres in the Oesophageal Cancer Clinical and Molecular Stratification consortium. CD8 and programmed death ligand 1 (PD-L1) immunohistochemical staining was assessed in matched resection specimens from 126 cases. Kaplan-Meier and Cox proportional hazards regression analysis were applied according to DDIR status for recurrence-free survival (RFS) and overall survival (OS).ResultsA total of 66 OAC samples (24%) were DDIR positive with the remaining 207 samples (76%) being DDIR negative. DDIR assay positivity was associated with improved RFS (HR: 0.61; 95% CI 0.38 to 0.98; p=0.042) and OS (HR: 0.52; 95% CI 0.31 to 0.88; p=0.015) following multivariate analysis. DDIR-positive patients had a higher pathological response rate (p=0.033), lower nodal burden (p=0.026) and reduced circumferential margin involvement (p=0.007). No difference in OS was observed according to DDIR status in an independent surgery-alone dataset.DDIR-positive OAC tumours were also associated with the presence of CD8+ lymphocytes (intratumoural: p<0.001; stromal: p=0.026) as well as PD-L1 expression (intratumoural: p=0.047; stromal: p=0.025).ConclusionThe DDIR assay is strongly predictive of benefit from DNA-damaging neoadjuvant chemotherapy followed by surgical resection and is associated with a proinflammatory microenvironment in OAC.
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| 16. |
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| 17. |
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| 18. |
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| 19. |
- Sohler, D, et al.
(författare)
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Neutron Excitations Across the N=50 Shell Gap in 102In
- 2002
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Ingår i: Nuclear Physics, Section A. - : Elsevier. - 0375-9474 .- 1873-1554. ; 708:3-4, s. 181-189
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Tidskriftsartikel (refereegranskat)abstract
- The structure of In-102 has been investigated by in-beam gamma-spectroscopic methods. Knowledge on the excited states of this nucleus has significantly been extended. Three cascades of transitions were observed to exceed the spin-energy domain spanned by the pig(9/2)(-1)v(d(5/2),g(7/2))(3) configurations. The new high spin states at similar to 4 MeV excitation energy could be assigned to the pig(9/2)(-1)v(d(5/2), g(7/2))(2)h (11/2) configuration, while at least those at 4.733, 5.192 and 5.853 MeV most likely arise from the vg(9/2) --> vd(5/2), g(7/2) one-particle-one-hole excitation across the N = 50 shell closure.
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| 20. |
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