| 11. |
- Lundblad, Patrik, 1982-, et al.
(författare)
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Interactive Visualization of Weather and Ship Data
- 2009
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Ingår i: Information Visualisation, 2009. - : IEEE. - 9780769537337 ; , s. 379-386
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Konferensbidrag (refereegranskat)abstract
- This paper focus on the development of a tool for Ship and Weather Information Monitoring (SWIM) visualizing weather data combined with data from ship voyages. The project was done in close collaboration with the Swedish Meteorological and Hydrological Institute (SMHI) who also evaluated the result. The goal was to implement a tool which will help shipping companies to monitor their fleet and the weather development along planned routes and provide support for decisions regarding route choice and to evade hazard. A qualitative usability study was performed to gather insight about usability issues and to aid future development. Overall the result of the study was positive and the users felt that the tool would aid them in the daily work.
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| 12. |
- Lundblad, Patrik, 1982-, et al.
(författare)
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Swedish Road Weather Visualization
- 2010
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Ingår i: Proceedings of the 14th International Conference Information Visualisation (IV), 2010. - : IEEE. - 9781424478460 ; , s. 313-321
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Konferensbidrag (refereegranskat)abstract
- The large and ever-increasing amounts of time-varying and geospatial digital weather information related to emergency scenarios that must be accessible to the public represent a major research challenge. A need to analyze and make decisions, often in time-critical situations, demand interactive web-enabled visualization tools that can aid the user to explore, communicate and publish visually large geo-information spaces. Geovisual analytics is an emerging research task facilitating dynamic time-linked visual representations that enable the users to simultaneously analyse relations among several different attributes with the aim to augment an analyst and decision-maker capabilities to assimilate complex situations and reach important knowledge. In this context, we introduce a web-enabled application for road weather visualization, a tool for analyzing and communicating information about road weather conditions particularly during the Swedish winter months. RoadVis is customized in close collaboration with domain experts from Swedish Meteorological and Hydrological Institute (SMHI) and the Swedish road administration facilitating a collection of dynamic map, weather and information visualization methods integrated with the Adobe© Flash© and Flex© development platform.
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| 13. |
- Lundblad, Patrik, 1982-, et al.
(författare)
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Visual Storytelling in Education Applied to Spatial-Temporal Multivariate Statistics Data
- 2012
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Ingår i: Expanding the Frontiers of Visual Analytics and Visualization. - London : Springer London. - 9781447128038 - 9781447128045 ; , s. 175-193
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Bokkapitel (refereegranskat)abstract
- The paper focuses on an ancient social ritual: “visual storytelling”—exemplified through telling stories about a country’s development over time that shape its economic growth and well-being. Discoveries are made that draw the user into reflecting on how life is lived—and may be improved—from one region to another. In addition, the user can interactively participate in the web-based process which is important to the education and dissemination of public statistics. A toolkit GAV Flash (geoanalytics visualization) is constructed which is programmed in Adobe’s ActionScript. This is the basis for the statistics information visualization application “World eXplorer”. This uses integrated storytelling and is based on multiple linked views and an integrated database link to the public World dataBank. This has more than 400 performance indicators for the time period 1960–2010. An interactive visual story mechanism assists teachers to improve a student’s knowledge through reflections on how life is lived by using a variety of demographics, such as healthcare, environment, and educational and economic indicators. Educators can develop interactive teaching material based on this storytelling mechanism. Integrated snapshots can be captured at any time during an explorative data analysis process and they become an important component of the analytical reasoning process. Students can access geovisual applications and explore statistical relations on their own guided by the stories prepared by the teachers. With the associated science of perception and cognition in relation to the use of multivariate spatio-temporal statistical data, this paper contributes to the growing interest in geovisual statistics analytics in education.
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| 14. |
- Lundblad, Patrik, et al.
(författare)
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Voyage Analysis Applied to Geovisual Analytics
- 2008
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Ingår i: Proceedings of the 12th IEEE International Conference on Information Visualisation. - Los Alamitos : IEEE Society Press. - 9780769532684 ; , s. 381-388
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Konferensbidrag (refereegranskat)abstract
- This paper demonstrates the synergy of common InfoVis and GeoVis interaction techniques and the logistic application domain demonstrated in the customized visualize performance data (VISPER) application. In VISPER multi-dimensional, multi-source, time-varying and geospatial digital information from voyage analysis is represented to facilitate decision-making. Using common InfoVis components for multivariate data together with logistics visualization in a new synergy aids the users in their work examining ship and route performance. An evaluation of the usability was performed to gather insights for future development. The results from the evaluation show that the overall impression of VISPER was highly positive and participants enjoyed using it. Feedback obtained was highly valuable and directly applicable for improvements and further development.
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| 15. |
- Nordström, Ulrika, et al.
(författare)
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Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease.
- 2015
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Ingår i: Neurobiology of Disease. - : Elsevier BV. - 0969-9961. ; 73, s. 70-82
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Tidskriftsartikel (refereegranskat)abstract
- Current research on Parkinson's disease (PD) pathogenesis requires relevant animal models that mimic the gradual and progressive development of neuronal dysfunction and degeneration that characterizes the disease. Polymorphisms in engrailed 1 (En1), a homeobox transcription factor that is crucial for both the development and survival of mesencephalic dopaminergic neurons, are associated with sporadic PD. This suggests that En1 mutant mice might be a promising candidate PD model. Indeed, a mouse that lacks one En1 allele exhibits decreased mitochondrial complex I activity and progressive midbrain dopamine neuron degeneration in adulthood, both features associated with PD. We aimed to further characterize the disease-like phenotype of these En1(+/-) mice with a focus on early neurodegenerative changes that can be utilized to score efficacy of future disease modifying studies. We observed early terminal defects in the dopaminergic nigrostriatal pathway in En1(+/-) mice. Several weeks before a significant loss of dopaminergic neurons in the substantia nigra could be detected, we found that striatal terminals expressing high levels of dopaminergic neuron markers TH, VMAT2, and DAT were dystrophic and swollen. Using transmission electron microscopy, we identified electron dense bodies consistent with abnormal autophagic vacuoles in these terminal swellings. In line with these findings, we detected an up-regulation of the mTOR pathway, concurrent with a downregulation of the autophagic marker LC3B, in ventral midbrain and nigral dopaminergic neurons of the En1(+/-) mice. This supports the notion that autophagic protein degradation is reduced in the absence of one En1 allele. We imaged the nigrostriatal pathway using the CLARITY technique and observed many fragmented axons in the medial forebrain bundle of the En1(+/-) mice, consistent with axonal maintenance failure. Using in vivo electrochemistry, we found that nigrostriatal terminals in the dorsal striatum were severely deficient in dopamine release and reuptake. Our findings support a progressive retrograde degeneration of En1(+/-) nigrostriatal neurons, akin to what is suggested to occur in PD. We suggest that using the En1(+/-) mice as a model will provide further key insights into PD pathogenesis, and propose that axon terminal integrity and function can be utilized to estimate dopaminergic neuron health and efficacy of experimental PD therapies.
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