| 11. |
- Moore, P. R., et al.
(författare)
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Advanced machine service support using Internet-enabled three-dimensional-based virtual engineering
- 2008
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Ingår i: International Journal of Production Research. - : Taylor & Francis. - 0020-7543 .- 1366-588X. ; 46:15, s. 4215-4235
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Tidskriftsartikel (refereegranskat)abstract
- In the era of globalization, one of the key factors for manufacturing machine builders/suppliers to remain competitive is their capability to provide cost-effective and comprehensive machine service and maintenance for their clients at anytime, anywhere. Previous research has highlighted the role of virtual engineering tools in the design and development life cycle of manufacturing machinery systems. Virtual engineering models created during the development phase can potentially be used to provide valuable functions for many other tasks during the operational phase, including service and maintenance support. This paper introduces an innovative Internet-enabled three-dimensional-based virtual engineering framework that can be used for such purposes. Specifically, it addresses a system architecture that is designed to facilitate the tight integration between virtual engineering tools and a set of Internet-based reconfigurable modular maintenance supporting tools. This system architecture has been verified by implementations using different toolsets atop of various Internet technologies (e.g. XML Web services and LabView's Datasocket). Implementation details and successful industrial-based test cases are also provided in this paper.
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| 12. |
- Ng, Amos, et al.
(författare)
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Virtual manufacturing for press line monitoring and diagnostics
- 2008
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Ingår i: International journal of machine tools & manufacture. - : Elsevier. - 0890-6955 .- 1879-2170. ; 48:5, s. 565-575
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Tidskriftsartikel (refereegranskat)abstract
- Virtual manufacturing, or manufacturing simulation, can be divided into three domains: product domain, process domain, and resource domain. This paper focuses on the use of virtual manufacturing for press line monitoring and diagnostics. It contains an introduction to virtual manufacturing, divided into a general part on modelling and simulation, verification, validation and acceptance, and the division into the three domains, as well as a specific part on the use of simulation in these domains for sheet metal products, processes and processing equipment. The main software tools discussed in this paper are discrete event simulation and computer-aided robotics; the designed and implemented machine service support system is an example of advanced use of three-dimensional (3-D) graphical simulation in the resource domain. This system offers remote on-line monitoring and diagnostics functions as well as media player-type functions such as replay that allow a service and maintenance expert to analyse disturbances that occur at remote locations. A key feature of the system is 3-D graphical simulation with I/O synchronisation. This type of system is particularly useful for system integrators and machine builders that install press lines and press cells world-wide and need to guarantee a high level of availability of the installed machinery.
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| 13. |
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| 14. |
- Sprangers, MAG, et al.
(författare)
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The establishment of the GENEQOL consortium to investigate the genetic disposition of patient-reported quality-of-life outcomes
- 2009
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Ingår i: Twin research and human genetics : the official journal of the International Society for Twin Studies. - : Cambridge University Press (CUP). - 1832-4274. ; 12:3, s. 301-311
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Tidskriftsartikel (refereegranskat)abstract
- To our knowledge, no comprehensive, interdisciplinary initiatives have been taken to examine the role of genetic variants on patient-reported quality-of-life outcomes. The overall objective of this paper is to describe the establishment of an international and interdisciplinary consortium, the GENEQOL Consortium, which intends to investigate the genetic disposition of patient-reported quality-of-life outcomes. We have identified five primary patient-reported quality-of-life outcomes as initial targets: negative psychological affect, positive psychological affect, self-rated physical health, pain, and fatigue. The first tangible objective of the GENEQOL Consortium is to develop a list of potential biological pathways, genes and genetic variants involved in these quality-of-life outcomes, by reviewing current genetic knowledge. The second objective is to design a research agenda to investigate and validate those genes and genetic variants of patient-reported quality-of-life outcomes, by creating large datasets. During its first meeting, the Consortium has discussed draft summary documents addressing these questions for each patient-reported quality-of-life outcome. A summary of the primary pathways and robust findings of the genetic variants involved is presented here. The research agenda outlines possible research objectives and approaches to examine these and new quality-of-life domains. Intriguing questions arising from this endeavor are discussed. Insight into the genetic versus environmental components of patient-reported quality-of-life outcomes will ultimately allow us to explore new pathways for improving patient care. If we can identify patients who are susceptible to poor quality of life, we will be able to better target specific clinical interventions to enhance their quality of life and treatment outcomes.
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| 15. |
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| 16. |
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| 17. |
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| 18. |
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| 19. |
- Syberfeldt, Anna, et al.
(författare)
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Simulation-Based Optimization of a Complex Mail Transportation Network
- 2008
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Ingår i: Proceedings of the 2008 Winter Simulation Conference. - New York : IEEE conference proceedings. - 9781424427086 ; , s. 2625-2631
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Konferensbidrag (refereegranskat)abstract
- The Swedish Postal Services receives and distributes over 22 million pieces of mail every day. Mail transportation takes place overnight by airplanes, trains, trucks, and cars in a transportation network comprising a huge number of possible routes. For testing and analysis of different transport solutions, a discrete-event simulation model of the transportation network has been developed. This paper describes the optimization of transport solutions using evolutionary algorithms coupled with the simulation model. The vast transportation network in combination with a large number of possible transportation configurations and conflicting optimization criteria make the optimization problem very challenging. A large number of simulation evaluations are needed before an acceptable solution is found, making the computational cost of the problem severe. To address this problem, a computationally cheap surrogate model is used to offload the optimization process.
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| 20. |
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