11. |
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12. |
- Aad, G., et al.
(författare)
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- 2012
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Tidskriftsartikel (refereegranskat)
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13. |
- Aad, G., et al.
(författare)
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- 2012
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swepub:Mat__t (refereegranskat)
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14. |
- Harner, Tom, et al.
(författare)
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Air synthesis review : polycyclic aromatic compounds in the oil sands region
- 2018
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Ingår i: Environmental Reviews. - : Canadian Science Publishing. - 1181-8700 .- 1208-6053. ; 26:4, s. 430-468
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Forskningsöversikt (refereegranskat)abstract
- This air synthesis review presents the current state of knowledge on the sources, fates, and effects for polycyclic aromatic compounds (PACs) and related chemicals released to air in the oil sands region (OSR) in Alberta, Canada. Through the implementation of the Joint Canada-Alberta Oil Sands Monitoring Program in 2012 a vast amount of new information on PACs has been acquired through directed monitoring and research projects and reported to the scientific community and public. This new knowledge addresses questions related to cumulative effects and informs the sustainable management of the oil sands resource while helping to identify gaps in understanding and priorities for future work. As a result of this air synthesis review on PACs, the following topics have been identified as new science priorities: (i) improving emissions reporting to better account for fugitive mining emissions of PACs that includes a broader range of PACs beyond the conventional polycyclic aromatic hydrocarbons (PAHs) including, inter alia, alkylated-PAHs (alk-PAHs), dibenzothiophene (DBT), alk-DBTs, nitro-PAHs, oxy-PAHs including quinones and thia-and aza-arenes; (ii) improving information on the ambient concentrations, long-range transport, and atmospheric deposition of these broader classes of PACs and their release (with co-contaminants) from different types of mining activities; (iii) further optimizing electricity-free and cost-effective approaches for assessing PAC deposition (e.g., snow sampling, lichens, passive ambient sampling) spatially across the OSR and downwind regions; (iv) designing projects that integrate monitoring efforts with source attribution models and ecosystem health studies to improve understanding of sources, receptors, and effects; (v) further optimizing natural deposition archives (e.g., sediment, peat, tree rings) and advanced forensic techniques (e.g., isotope analysis, marker compounds) to provide better understanding of sources of PACs in the OSR over space and time; (vi) conducting process research to improve model capabilities for simulating atmospheric chemistry of PACs and assessing exposure to wildlife and humans; and (vii) developing tools and integrated strategies for assessing cumulative risk to wildlife and humans by accounting for the toxicity of the mixture of chemicals in air rather than on a single compound basis.
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15. |
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16. |
- Khastieva, Dina, et al.
(författare)
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Value of energy storage for transmission investments
- 2019
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Ingår i: Energy Strategy Reviews. - : Elsevier. - 2211-467X .- 2211-4688. ; 24, s. 94-110
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Tidskriftsartikel (refereegranskat)abstract
- This paper investigates joint investment planning of transmission lines and energy storage. Energy storage can be seen as a complement to transmission infrastructure and can be used for transmission deferral. On the other hand, under certain conditions, when the expected profit of both sectors depends on congestion in the system, transmission and energy storage can be seen as competitors. The transmission sector is in this study assumed to be a natural monopoly and operation and planning of transmission lines is performed by an independent company whereas the energy storage owner company operates and invests under competitive market rules. Three main questions are addressed in this paper. First of all, will additional energy storage capacity contribute to the growth of social welfare? Second, how will incentive regulation of the transmission network affect the need for energy storage? Third, how will the choice of incentive regulation affect the value of energy storage. This paper first provides an overview of incentive regulation which can be applied to transmission investments. Then case studies based on a 6-node power system network and the IEEE 118-node system are proposed in order to answer the aforementioned questions. The results of the case studies show that energy storage investments complement transmission expansion and contribute to higher social welfare values. The benefits from energy storage investments are significantly higher under two investigated incentive regulations as compared to the case without incentive regulation. Thus, the transmission investment planning process should consider energy storage options.
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17. |
- Klionsky, DJ, et al.
(författare)
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Autophagy in major human diseases
- 2021
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Ingår i: The EMBO journal. - : EMBO. - 1460-2075 .- 0261-4189. ; 40:19, s. e108863-
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Tidskriftsartikel (refereegranskat)
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18. |
- Klionsky, Daniel J., et al.
(författare)
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Guidelines for the use and interpretation of assays for monitoring autophagy
- 2012
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Ingår i: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 8:4, s. 445-544
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Forskningsöversikt (refereegranskat)abstract
- In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
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19. |
- Lee, Ki-ahm, et al.
(författare)
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Highly oscillating thin obstacles
- 2013
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Ingår i: Advances in Mathematics. - : Elsevier BV. - 0001-8708 .- 1090-2082. ; 237, s. 286-315
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Tidskriftsartikel (refereegranskat)abstract
- The focus of this paper is on a thin obstacle problem where the obstacle is defined on the intersection between a hyper-plane Gamma in R-n and a periodic perforation T-epsilon of R-n, depending on a small parameters epsilon > 0. As epsilon -> 0, it is crucial to estimate the frequency of intersections and to determine this number locally. This is done using strong tools from uniform distribution. By employing classical estimates for the discrepancy of sequences of type {k alpha}(k=1)(infinity), alpha is an element of R, we are able to extract rather precise information about the set Gamma boolean AND T-epsilon. As epsilon -> 0, we determine the limit u of the solution u(epsilon) to the obstacle problem in the perforated domain, in terms of a limit equation it solves. We obtain the typical "strange term" behavior for the limit problem, but with a different constant taking into account the contribution of all different intersections, that we call the averaged capacity. Our result depends on the normal direction of the plane, but holds for a.e. normal on the unit sphere in R-n.
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20. |
- Marschall, Gosia
(författare)
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Teacher self-efficacy sources during initial teacher education
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- This paper reports on the role of self-efficacy sources in the development of teacher self- efficacy of four pre-service secondary mathematics teachers. The results revealed that all four self-efficacy sources were significant in the process, particularly for those individuals who were vulnerable. They also indicated that broadening of the current conceptualisation of physiological and affective states, and vicarious experiences as self-efficacy sources is necessary to uncover the nuances and aid understanding of the process of teacher self- efficacy development. Collectively, the results contribute to the field of teacher self-efficacy in new, previously unreported ways.
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