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Sökning: WFRF:(Nagashima T.)

  • Resultat 11-20 av 23
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11.
  • Fan, G. W., et al. (författare)
  • Structure of 8Li from a reaction cross-section measurement
  • 2014
  • Ingår i: Phys. Rev. C. - American Physical Society. ; 90, s. 044321-
  • Tidskriftsartikel (refereegranskat)abstract
    • We have precisely measured reaction cross sections (σR) for 8Li using 9Be, 12C, 27Al, and proton targets at intermediate energies by the transmission method. From the energy dependence of the σR including the high energy data, the density distribution of 8Li was deduced through a modified Glauber model. It is shown that 8Li has a shorter tail structure in the density as compared with that of 8B and the matter radius of 8Li is similar to those of the other nonhalo Li isotopes. The result is consistent with the previous experiments that there is a tendency for 8Li to be a skin nucleus.
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  • Mazur, Mikael, 1990, et al. (författare)
  • Real-Time MIMO Transmission over Field-Deployed Coupled-Core Multi-Core Fibers
  • 2022
  • Ingår i: 2022 Optical Fiber Communications Conference and Exhibition, OFC 2022 - Proceedings. - 9781943580071
  • Konferensbidrag (refereegranskat)abstract
    • We perform parallel continuous measurements of deployed SDM fibers using real-time coherent receivers implemented on FPGAs. Fast readouts enabling real-time tracking of the DSP implementation, showing that coupled-core fibers are compatible with real-time DSP implementations.
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  • Yamaguchi, T., et al. (författare)
  • Energy-dependent charge-changing cross sections and proton distribution of 28Si
  • 2010
  • Ingår i: Phys. Rev. C. ; 82, s. 014609-1-014609-6
  • Tidskriftsartikel (refereegranskat)abstract
    • The charge-changing cross sections (σcc) of 28Si on a carbon target were measured with high precision atintermediate energies from 100 to 600 MeV/nucleon. The measured σcc decreases rapidly from low energies upto 200 MeV/nucleon, whereas at higher energies it appears almost constant. The energy dependence of σcc iscompared with a Glauber-type model calculation where only the proton distribution of 28Si is taken into account.A phenomenological correction factor deduced from the present data satisfactorily reproduces the experimentalσcc for other stable nuclei, whose charge distributions were determined by electron scattering and muon captureexperiments.
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16.
  • Farrow, R., et al. (författare)
  • GO-GN Conceptual Frameworks Guide
  • 2021
  • Bok (övrigt vetenskapligt/konstnärligt)abstract
    • If you’re a doctoral researcher (in any discipline) or someone who produces research in a professional capacity you’ve perhaps encountered the phrase “conceptual framework”. Sometimes a whole chapter of a Ph.D or Ed.D might be given over to investigating the relevance of different frameworks for an area of inquiry, or to synthesizing several frameworks together to ground the approach taken to answering a specific research question. Alternatively, you might not have heard much mention of conceptual frameworks or how they relate to what you are trying to achieve with your research. A conceptual framework brings together a set of ideas and articulates the different concepts that will be used in a study or research project. Because this is highly contextual - and often specific to a particular research question or approach - there aren’t really any general rules that cover how to do this. In addition, there is a lot of ambiguity and impreciseness in the language used to describe this stuff. Sometimes people talk about theoretical frameworks, or models, or a ‘theory of action’ that guides their research project. But do these mean different things? And are there differences between disciplines? In an empirical project the conceptual framework might be used to determine the kinds of questions to ask in a survey, or which data points to collect and focus on. A conceptual framework might be used to generate a hypothesis that is to be tested, or to facilitate the interpretation of results. On the qualitative side a conceptual framework might be used to provide the right kinds of descriptions at different stages of the research process; to identify or explore categories of analysis; or to guide and refine the conclusions drawn by a study. All of these things can happen in a single project! Given the importance and centrality of these frameworks, it might be surprising to learn that relatively little has been written about using them in research. There’s certainly a lot less published about this than research methods or methodology, for instance. (Though different methods often come with specific conceptual frameworks built in or with a more obvious alignment). So, to start making sense of all this we begin by looking at some of the papers that offer systematic guidance or understanding of the role of conceptual frameworks in research. As this guide progresses we’ll bring in perspectives from GO-GN members on their experiences with developing and using conceptual frameworks.
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18.
  • Morita, M, et al. (författare)
  • Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis
  • 2019
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 1091-6490. ; 116:16, s. 7973-7981
  • Tidskriftsartikel (refereegranskat)abstract
    • Whole-body metabolic homeostasis is tightly controlled by hormone-like factors with systemic or paracrine effects that are derived from nonendocrine organs, including adipose tissue (adipokines) and liver (hepatokines). Fibroblast growth factor 21 (FGF21) is a hormone-like protein, which is emerging as a major regulator of whole-body metabolism and has therapeutic potential for treating metabolic syndrome. However, the mechanisms that control FGF21 levels are not fully understood. Herein, we demonstrate that FGF21 production in the liver is regulated via a posttranscriptional network consisting of the CCR4–NOT deadenylase complex and RNA-binding protein tristetraprolin (TTP). In response to nutrient uptake, CCR4–NOT cooperates with TTP to degrade AU-rich mRNAs that encode pivotal metabolic regulators, including FGF21. Disruption of CCR4–NOT activity in the liver, by deletion of the catalytic subunit CNOT6L, increases serum FGF21 levels, which ameliorates diet-induced metabolic disorders and enhances energy expenditure without disrupting bone homeostasis. Taken together, our study describes a hepatic CCR4–NOT/FGF21 axis as a hitherto unrecognized systemic regulator of metabolism and suggests that hepatic CCR4–NOT may serve as a target for devising therapeutic strategies in metabolic syndrome and related morbidities.
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  • Resultat 11-20 av 23

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