| 11. |
- Silventoinen, Karri, et al.
(författare)
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Genetic and environmental variation in educational attainment : an individual-based analysis of 28 twin cohorts
- 2020
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 10:1
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Tidskriftsartikel (refereegranskat)abstract
- We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural–geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at 25 years of age or older. Genetic factors explained the major part of individual differences in educational attainment (heritability: a2 = 0.43; 0.41–0.44), but also environmental variation shared by co-twins was substantial (c2 = 0.31; 0.30–0.33). The proportions of educational variation explained by genetic and shared environmental factors did not differ between Europe, North America and Australia, and East Asia. When restricted to twins 30 years or older to confirm finalized education, the heritability was higher in the older cohorts born in 1900–1949 (a2 = 0.44; 0.41–0.46) than in the later cohorts born in 1950–1989 (a2 = 0.38; 0.36–0.40), with a corresponding lower influence of common environmental factors (c2 = 0.31; 0.29–0.33 and c2 = 0.34; 0.32–0.36, respectively). In conclusion, both genetic and environmental factors shared by co-twins have an important influence on individual differences in educational attainment. The effect of genetic factors on educational attainment has decreased from the cohorts born before to those born after the 1950s.
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| 12. |
- Yokoyama, Yoshie, et al.
(författare)
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Genetic and environmental factors affecting birth size variation : A pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts
- 2018
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Ingår i: International Journal of Epidemiology. - : Oxford University Press (OUP). - 0300-5771 .- 1464-3685. ; 47:4, s. 1195-1206
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Tidskriftsartikel (refereegranskat)abstract
- Background: The genetic architecture of birth size may differ geographically and over time. We examined differences in the genetic and environmental contributions to birthweight, length and ponderal index (PI) across geographical-cultural regions (Europe, North America and Australia, and East Asia) and across birth cohorts, and how gestational age modifies these effects. Methods: Data from 26 twin cohorts in 16 countries including 57 613 monozygotic and dizygotic twin pairs were pooled. Genetic and environmental variations of birth size were estimated using genetic structural equation modelling. Results: The variance of birthweight and length was predominantly explained by shared environmental factors, whereas the variance of PI was explained both by shared and unique environmental factors. Genetic variance contributing to birth size was small. Adjusting for gestational age decreased the proportions of shared environmental variance and increased the propositions of unique environmental variance. Genetic variance was similar in the geographical-cultural regions, but shared environmental variance was smaller in East Asia than in Europe and North America and Australia. The total variance and shared environmental variance of birth length and PI were greater from the birth cohort 1990-99 onwards compared with the birth cohorts from 1970-79 to 1980-89. Conclusions: The contribution of genetic factors to birth size is smaller than that of shared environmental factors, which is partly explained by gestational age. Shared environmental variances of birth length and PI were greater in the latest birth cohorts and differed also across geographical-cultural regions. Shared environmental factors are important when explaining differences in the variation of birth size globally and over time.
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| 13. |
- Daranciang, Dan, et al.
(författare)
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Ultrafast Photovoltaic Response in Ferroelectric Nanolayers
- 2012
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Ingår i: Physical Review Letters. - 1079-7114. ; 108:8
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Tidskriftsartikel (refereegranskat)abstract
- We show that light drives large-amplitude structural changes in thin films of the prototypical ferroelectric PbTiO3 via direct coupling to its intrinsic photovoltaic response. Using time-resolved x-ray scattering to visualize atomic displacements on femtosecond time scales, photoinduced changes in the unit-cell tetragonality are observed. These are driven by the motion of photogenerated free charges within the ferroelectric and can be simply explained by a model including both shift and screening currents, associated with the displacement of electrons first antiparallel to and then parallel to the ferroelectric polarization direction.
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| 14. |
- El-Sayed, Najib M., et al.
(författare)
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The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease.
- 2005
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 309:5733, s. 409-15
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Tidskriftsartikel (refereegranskat)abstract
- Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 represent allelic pairs. Over 50% of the genome consists of repeated sequences, such as retrotransposons and genes for large families of surface molecules, which include trans-sialidases, mucins, gp63s, and a large novel family (>1300 copies) of mucin-associated surface protein (MASP) genes. Analyses of the T. cruzi, T. brucei, and Leishmania major (Tritryp) genomes imply differences from other eukaryotes in DNA repair and initiation of replication and reflect their unusual mitochondrial DNA. Although the Tritryp lack several classes of signaling molecules, their kinomes contain a large and diverse set of protein kinases and phosphatases; their size and diversity imply previously unknown interactions and regulatory processes, which may be targets for intervention.
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| 15. |
- Ksenzov, Dmitriy, et al.
(författare)
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Nanoscale Transient Magnetization Gratings Created and Probed by Femtosecond Extreme Ultraviolet Pulses
- 2021
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Ingår i: Nano Letters. - : American Chemical Society (ACS). - 1530-6984 .- 1530-6992. ; 21:7, s. 2905-2911
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Tidskriftsartikel (refereegranskat)abstract
- We utilize coherent femtosecond extreme ultraviolet (EUV) pulses from a free electron laser (FEL) to generate transient periodic magnetization patterns with periods as short as 44 nm. Combining spatially periodic excitation with resonant probing at the M-edge of cobalt allows us to create and probe transient gratings of electronic and magnetic excitations in a CoGd alloy. In a demagnetized sample, we observe an electronic excitation with a rise time close to the FEL pulse duration and similar to 0.5 ps decay time indicative of electron-phonon relaxation. When the sample is magnetized to saturation in an external field, we observe a magnetization grating, which appears on a subpicosecond time scale as the sample is demagnetized at the maxima of the EUV intensity and then decays on the time scale of tens of picoseconds via thermal diffusion. The described approach opens multiple avenues for studying dynamics of ultrafast magnetic phenomena on nanometer length scales.
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| 16. |
- Chomiuk, Laura, et al.
(författare)
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Classical Novae at Radio Wavelengths
- 2021
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Ingår i: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 257:2
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Tidskriftsartikel (refereegranskat)abstract
- We present radio observations (1-40 GHz) for 36 classical novae, representing data from over five decades compiled from the literature, telescope archives, and our own programs. Our targets display a striking diversity in their optical parameters (e.g., spanning optical fading timescales, t (2) = 1-263 days), and we find a similar diversity in the radio light curves. Using a brightness temperature analysis, we find that radio emission from novae is a mixture of thermal and synchrotron emission, with nonthermal emission observed at earlier times. We identify high brightness temperature emission (T ( B ) > 5 x 10(4) K) as an indication of synchrotron emission in at least nine (25%) of the novae. We find a class of synchrotron-dominated novae with mildly evolved companions, exemplified by V5589 Sgr and V392 Per, that appear to be a bridge between classical novae with dwarf companions and symbiotic binaries with giant companions. Four of the novae in our sample have two distinct radio maxima (the first dominated by synchrotron and the later by thermal emission), and in four cases the early synchrotron peak is temporally coincident with a dramatic dip in the optical light curve, hinting at a common site for particle acceleration and dust formation. We publish the light curves in a machine-readable table and encourage the use of these data by the broader community in multiwavelength studies and modeling efforts.
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| 17. |
- Nelson, Keith E., et al.
(författare)
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Lessons for Educational Designs from Dynamic-Systems-Inspired Experimental Acceleration of Children's Learning in Diverse Domains
- 2015
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Ingår i: Society for Research in Child Development, Biennial Meeting, March 19-23, Philadelphia, Pennsylvania, USA.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Dynamic Tricky Mix Theory emphasizes that multiple complex conditions need to “cooperate” and converge to support learning (Khan, Nelson, & Whyte, 2014; Nelson, 1991a, 2001, 2002; Nelson & Arkenberg, 2008; Nelson, Heiman, & Tjus, 1997). This convergence is a dynamic process, requiring coordination in real time episodes (cf. Damasio, 1999; Thelen & Smith, 1994). Children will LEARN only when there is some above-threshold level of dynamic convergence of learning conditions. The LEARN acronym is just one way of organizing these partly-overlapping categories of conditions: Launching/Challenging opportunities Enhancing (e.g. scaffolding strategies), Adjustment (Social-Emotion-Identity), Readiness, Networks (high current activation). The Dynamic Tricky Mix model helps to differentiate—among many potentially supportive patterns—interactive patterns that fail to support learning, those that support modest rates of learning, and those that scaffold the highest rates of learning. Learning of first language structures of syntax and vocabulary and narrative, sign language, second languages, literacy, and art skills are all considered here within our variant of dynamic system theorizing. We argue that across all learning domains studied here using causal experiments, the patterns of dynamic mixes leading to rapid developmental progress are strikingly similar.
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| 18. |
- Olierook, Hugo K.H., et al.
(författare)
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Age and geochemistry of magmatism on the oceanic Wallaby Plateau and implications for the opening of the Indian Ocean
- 2015
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Ingår i: Geology. - 0091-7613 .- 1943-2682. ; 43:11, s. 971-974
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Tidskriftsartikel (refereegranskat)abstract
- The temporal relationship between tectonic and volcanic activity on passive continental margins immediately before and after the initiation of mid-ocean ridge spreading is poorly understood because of the scarcity of volcanic samples on which to perform isotope geochronology. We present the first accurate geochronological constraints from a suite of volcanic and volcaniclastic rocks dredged from the 70,000 km2 submerged Wallaby Plateau situated on the Western Australian passive margin. Plagioclase 40Ar/39Ar and zircon U-Pb sensitive high-resolution ion microprobe ages indicate that a portion of the plateau formed at ca. 124 Ma. These ages are at least 6 m.y. younger than the oldest oceanic crust in adjacent abyssal plains (minimum = 130 Ma). Geochemical data indicate that the Wallaby Plateau volcanic samples are enriched tholeiitic basalt, similar to continental flood basalts, including the spatially and temporally proximal Bunbury Basalt in southwestern Australia. Thus, the Wallaby Plateau volcanism could be regarded as a (small) flood basalt event on the order of 104–105 km3. We suggest that magma could not erupt prior to 124 Ma because of the lack of space adjacent to the plateau. Eruption was made possible at 124 Ma via the opening of the Indian Ocean during the breakup of Greater India and Australia along the Wallaby-Zenith Fracture Zone. The scale of volcanism and the temporal proximity to breakup challenges the prevailing theory that the Western Australian margin formed as a volcanic passive margin. Given that the volume of volcanism is too small for typical flood basalts associated with volcanic passive margins, we suggest that the two end members, magma-poor and volcanic passive margins, should rather be treated as a continuum.
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