| 11. |
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| 12. |
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| 13. |
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| 14. |
- Dahlgren, Peter, et al.
(författare)
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From public spheres to civic cultures: young citizens' internet use
- 2007
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Ingår i: Media and Public Spheres. - 9780230007215 ; , s. 198-211
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Bokkapitel (refereegranskat)abstract
- From a deptrture in the public sphere perspective, this chapter explores how youg citizens , via their use of the internet, develop alternative political practices and identities, thereby contributing to new forms of civic cuoltures
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| 15. |
- Frykholm, Joel, 1977-
(författare)
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Framing the Feature Film : Multi-Reel Feature Film and American Film Culture in the 1910s
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This dissertation addresses the breakthrough of the multi-reel feature film in the United States, and the significance of this process within the wider context of the American film industry and culture in the 1910s. The purpose is to provide a new, and more comprehensive analytical framing of the topic, and to enhance our understanding of how a new central commodity, i.e. the multi-reel feature film, changed the conditions for film exhibition and reception. The introduction links the breakthrough of the multi-reel feature film to an array of film-historical transformations unfolding in the US around the same time. A critical assessment of previous scholarly work dealing with the early feature is also provided. Part I analyzes how the breakthrough of the multi-reel feature film was negotiated within the trade and by contemporary commentators. The result is a multi-perspective framing of the topic that highlights the complexity of these cultural negotiations and the uncertainty over cinema’s possible futures. Part II shifts attention to film culture and film exhibition in Philadelphia around 1914. The objective of this case study, largely based on newspaper sources, is to examine how the increasingly common multi-reel feature film was integrated into and/or changed the existing film culture in the city. The main conclusion is that experimentation and diversity rather than smooth transitions characterized the local response to the emergence of features. Part III deepens the investigation of local diversity by offering a case study of one particular film: The Spoilers (Selig Polyscope Co., 1914). The conditions of the film’s historical reception are outlined, and particular attention is given to the film’s role in the Americanization of the feature film market.
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| 16. |
- Goldstein, Alisa M., et al.
(författare)
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High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL
- 2006
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Ingår i: Cancer Research. - 1538-7445 .- 0008-5472. ; 66:20, s. 9818-9828
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Tidskriftsartikel (refereegranskat)abstract
- GenoMEL, comprising major familial melanoma research groups from North America, Europe, Asia, and Australia has created the largest familial melanoma sample yet available to characterize mutations in the high-risk melanoma susceptibility genes CDKN2A/alternate reading frames (ARF), which encodes p16 and p14ARF, and CDK4 and to evaluate their relationship with pancreatic cancer (PC), neural system tumors (NST), and uveal melanoma (UM). This study included 466 families (2,137 patients) with at least three melanoma patients from 17 GenoMEL centers. Overall, 41% (n = 190) of families had mutations; most involved p16 (n = 178). Mutations in CDK4 (n = 5) and ARF (n = 7) occurred at similar frequencies (2-3%). There were striking differences in mutations across geographic locales. The proportion of families with the most frequent founder mutation(s) of each locale differed significantly across the seven regions (P = 0.0009). Single founder CDKN2A mutations were predominant in Sweden (p.R112_L113insR, 92% of family's mutations) and the Netherlands (c.225_243del19, 90% of family's mutations). France, Spain, and Italy had the same most frequent mutation (p.G101W). Similarly, Australia and United Kingdom had the same most common mutations (p.M53I, cdVS2-105A > G, p.R24P, and p.L32P). As reported previously, there was a strong association between PC and CDKN2A mutations (P < 0.0001). This relationship differed by mutation. In contrast, there was little evidence for an association between CDKN2A mutations and NST (P = 0.52) or UM (P = 0.25). There was a marginally significant association between NST and ARF (P = 0.05). However, this particular evaluation had low power and requires confirmation. This GenoMEL study provides the most extensive characterization of mutations in high-risk melanoma susceptibility genes in families with three or more melanoma patients yet available.
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| 17. |
- Jensen, Richard A., et al.
(författare)
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Multiple factors affect the loss of measurable C-peptide over 6 years in newly diagnosed 15- to 35-year-old diabetic subjects
- 2007
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Ingår i: Journal of diabetes and its complications. - : Elsevier BV. - 1056-8727 .- 1873-460X. ; 21:4, s. 205-213
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this study is to identify risk factors for the loss of measurable plasma C-peptide in newly diagnosed 15- to 35-year-old diabetic subjects. Methods: This Swedish study included 778 subjects. C-peptide levels were obtained each year for 6 years after diagnosis. Loss of measurable C-peptide was defined as a level at or below the lower detection limit of the local assay (0.13 nmol/l). In addition to C-peptide, other baseline covariates included gender, age, body mass index, HLA genotype, and autoantibody levels. Results: Compared with autoantibody-negative subjects, autoantibody-positive subjects had lower median baseline C-peptide (0.27 vs. 0.50, P<001), their levels declined over the study period, and the risk of losing measurable C-peptide was significantly higher when more than one autoantibody was present [odds ratio (OR), 4.0; 95% confidence interval (CI), 2.13-7.54]. Among autoantibody-positive individuals, the presence of GAD65Ab (OR, 1.8; 95% Cl, 1.24-2.51) and islet cell antibodies (OR, 1.6; 95% CI, 1.19-2.18) conferred a higher risk for loss of measurable C-peptide as did female gender (OR, 1.6; 95% CI, 1.17-2.11) and time after diagnosis (OR, 1.5 for each additional year postdiagnosis; 95% CI, 1.41-1.57). Higher baseline C-peptide levels were protective (OR, 0.5 for each additional log nanomoles per liter; 95% CI, 0.36-0.58). Conclusions: This study identified autoantibody status, gender, and baseline C-peptide levels as factors that will be useful for predicting the disease course of 15- to 35-year-old diabetic individuals.
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| 18. |
- Johnsson, Richard, et al.
(författare)
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Reductive openings of acetals: Explanation of regioselectivity in borane reductions by mechanistic studies
- 2008
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Ingår i: Journal of Organic Chemistry. - : American Chemical Society (ACS). - 1520-6904 .- 0022-3263. ; 73:14, s. 5226-5232
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Tidskriftsartikel (refereegranskat)abstract
- The mechanisms of regioselective reductive openings of acetals were investigated in several model systems by a combination of Hammett plots, kinetic experiments, density functional calculations, and B-11 NMR. The regioselectivity of borane reductions of cyclic acetals can be controlled by the choice of borane. Lewis acid activation of BH3 center dot NMe3 increases the reaction rate and renders the borane the most electrophilic species, which associates to the more electron-rich oxygen of the acetal. In contrary, without activation, the regioselectivity is instead directed by the Lewis acid, as exemplified by the reaction with BH3 center dot THF.
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| 19. |
- Jänis, Anna, 1970, et al.
(författare)
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Microwave absorbing properties of ferrite-based nanocomposites
- 2007
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Ingår i: Behavior and Mechanics of Multifunctional and Composite Materials 2007. - : SPIE - International Society for Optical Engineering. - 0819466476 - 9780819466471 ; , s. 65261P-
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Konferensbidrag (refereegranskat)abstract
- A study of the microwave absorbing properties of polymer (epoxy) based nanocomposites is presented. The ferrite nanoparticles employed as filler materials were produced by a co-precipitation method, which was designed for production of large amounts at low cost. The absorbing properties of different kinds of ferrite nanoparticles, soft (manganese) and hard (cobalt) magnetic nanoparticles, are compared. In addition, the impact of high and low densities of the respective ferrite type has been investigated. Our analysis of the microwave absorbing properties is made over a wide frequency band including both MHz and GHz regions, which is of high interest for a number of different applications both military and civilian.
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| 20. |
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