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Numrering	Referens	Omslagsbild	Hitta
11.	Mancia, G, et al. (författare) 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) 2013 Ingår i: Journal of hypertension. - : Ovid Technologies (Wolters Kluwer Health). - 1473-5598 .- 0263-6352. ; 31:7, s. 1281-1357 Tidskriftsartikel (refereegranskat)
12.	Cosentino, F, et al. (författare) 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD 2020 Ingår i: European heart journal. - : Oxford University Press (OUP). - 1522-9645 .- 0195-668X. ; 41:2, s. 255-323 Tidskriftsartikel (refereegranskat)
13.	Maqdasy, S, et al. (författare) Impaired phosphocreatine metabolism in white adipocytes promotes inflammation 2022 Ingår i: Nature metabolism. - 2522-5812. ; 4:2, s. 190-202 Tidskriftsartikel (refereegranskat)
14.	Shen, J. X., et al. (författare) 3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis 2021 Ingår i: Advanced Science. - : Wiley. - 2198-3844. ; 8:16 Tidskriftsartikel (refereegranskat)abstract Obesity and type 2 diabetes are strongly associated with adipose tissue dysfunction and impaired adipogenesis. Understanding the molecular underpinnings that control adipogenesis is thus of fundamental importance for the development of novel therapeutics against metabolic disorders. However, translational approaches are hampered as current models do not accurately recapitulate adipogenesis. Here, a scaffold-free versatile 3D adipocyte culture platform with chemically defined conditions is presented in which primary human preadipocytes accurately recapitulate adipogenesis. Following differentiation, multi-omics profiling and functional tests demonstrate that 3D adipocyte cultures feature mature molecular and cellular phenotypes similar to freshly isolated mature adipocytes. Spheroids exhibit physiologically relevant gene expression signatures with 4704 differentially expressed genes compared to conventional 2D cultures (false discovery rate < 0.05), including the concerted expression of factors shaping the adipogenic niche. Furthermore, lipid profiles of >1000 lipid species closely resemble patterns of the corresponding isogenic mature adipocytes in vivo (R2 = 0.97). Integration of multi-omics signatures with analyses of the activity profiles of 503 transcription factors using global promoter motif inference reveals a complex signaling network, involving YAP, Hedgehog, and TGFβ signaling, that links the organotypic microenvironment in 3D culture to the activation and reinforcement of PPARγ and CEBP activity resulting in improved adipogenesis.
15.	Graham, I., et al. (författare) European guidelines on cardiovascular disease prevention in clinical practice: executive summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (Constituted by representatives of nine societies and by invited experts) 2007 Ingår i: Eur J Cardiovasc Prev Rehabil. ; 14:suppl 2 Tidskriftsartikel (refereegranskat)
16.	Heggebo, L. C., et al. (författare) Investigating survival, quality of life and cognition in PROton versus photon therapy for IDH-mutated diffuse grade 2 and 3 GLIOmas (PRO-GLIO): a randomised controlled trial in Norway and Sweden 2023 Ingår i: Bmj Open. - : BMJ. - 2044-6055. ; 13:3 Tidskriftsartikel (refereegranskat)abstract IntroductionThe use of proton therapy increases globally despite a lack of randomised controlled trials demonstrating its efficacy and safety. Proton therapy enables sparing of non-neoplastic tissue from radiation. This is principally beneficial and holds promise of reduced long-term side effects. However, the sparing of seemingly non-cancerous tissue is not necessarily positive for isocitrate dehydrogenase (IDH)-mutated diffuse gliomas grade 2-3, which have a diffuse growth pattern. With their relatively good prognosis, yet incurable nature, therapy needs to be delicately balanced to achieve a maximal survival benefit combined with an optimised quality of life.Methods and analysisPRO-GLIO (PROton versus photon therapy in IDH-mutated diffuse grade 2 and 3 GLIOmas) is an open-label, multicentre, randomised phase III non-inferiority study. 224 patients aged 18-65 years with IDH-mutated diffuse gliomas grade 2-3 from Norway and Sweden will be randomised 1:1 to radiotherapy delivered with protons (experimental arm) or photons (standard arm). First intervention-free survival at 2 years is the primary endpoint. Key secondary endpoints are fatigue and cognitive impairment, both at 2 years. Additional secondary outcomes include several survival measures, health-related quality of life parameters and health economy endpoints.Ethics and disseminationTo implement proton therapy as part of standard of care for patients with IDH-mutated diffuse gliomas grade 2-3, it should be deemed safe. With its randomised controlled design testing proton versus photon therapy, PRO-GLIO will provide important information for this patient population concerning safety, cognition, fatigue and other quality of life parameters. As proton therapy is considerably more costly than its photon counterpart, cost-effectiveness will also be evaluated. PRO-GLIO is approved by ethical committees in Norway (Regional Committee for Medical & Health Research Ethics) and Sweden (The Swedish Ethical Review Authority) and patient inclusion has commenced. Trial results will be published in international peer-reviewed journals, relevant conferences, national and international meetings and expert forums.Trial registration numberClinicalTrials.gov Registry (NCT05190172).
17.	Ryden, L, et al. (författare) Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD) 2007 Ingår i: European heart journal. - : Oxford University Press (OUP). - 0195-668X .- 1522-9645. ; 28:1, s. 88-136 Tidskriftsartikel (refereegranskat)
18.	Ryden, L, et al. (författare) Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: full text 2007 Ingår i: EUROPEAN HEART JOURNAL SUPPLEMENTS. - : Oxford University Press (OUP). - 1520-765X. ; 9:C, s. C3-C74 Forskningsöversikt (övrigt vetenskapligt/konstnärligt)
19.	Vaittinen, M, et al. (författare) MFAP5 is related to obesity-associated adipose tissue and extracellular matrix remodeling and inflammation 2015 Ingår i: Obesity (Silver Spring, Md.). - : Wiley. - 1930-739X .- 1930-7381. ; 23:7, s. 1371-1378 Tidskriftsartikel (refereegranskat)
20.	Valentine, JM, et al. (författare) β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity 2022 Ingår i: The Journal of clinical investigation. - 1558-8238. ; 132:2 Tidskriftsartikel (refereegranskat)

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