| 11. |
- Saarela, Jan, et al.
(författare)
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Ethnic Composition of Couples and Mutual Health Benefit Receipt : Register-Based Evidence from Finland
- 2022
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Ingår i: International Journal of Environmental Research and Public Health. - : MDPI AG. - 1661-7827 .- 1660-4601. ; 19:1
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Tidskriftsartikel (refereegranskat)abstract
- The literature on health dependencies among partners typically ignores diversity of partnership characteristics. One salient example is the ethnic composition. We extend prior work on partnerships and health by investigating how married and cohabiting partners mutually influence each other’s receipt of health-related benefits, focusing on how such correlations vary with the couple’s ethnic composition. We study partners’ mutual receipt of sickness allowance and disability pension in ethnically endogamous and exogamous couples in Finland. The population consists of native individuals in similar socioeconomic positions but belonging to two different ethnic groups—Finnish and Swedish speakers—who differ in health and family life. Using data from population registers, we estimate discrete-time hazard models for first-time benefit receipt, as related to partner’s benefit receipt, among midlife couples. We found evidence of mutual receipt of health benefits in both endogamous and exogamous couples, the correlation being strongest for disability pension. Partner correlation in disability pension receipt is slightly stronger in endogamous Swedish than in endogamous Finnish couples, while women in exogamous couples are slightly less sensitive to men’s receipt than vice versa. The results show that mutual health may be heterogeneous across couples that differ in ethnic composition.
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| 12. |
- Saarela, Jan, et al.
(författare)
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Ethnic Composition of Couples and Mutual Health Benefit Receipt: Register-Based Evidence from Finland
- 2021
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- We study partners’ mutual receipt of sickness allowance and disability pension in ethnically endogamous and exogamous couples in Finland. The population consists of native individuals in similar socioeconomic positions but belonging to two different ethnic groups, Finnish and Swedish speakers, which differ regarding health and cultural practices related to family life. Using data from population registers (1987-2011, n = 36,034 couples), we estimate discrete-time hazard models for first-time benefit receipt related to partner’s benefit receipt amongmidlife couples. We find evidence of mutual receipt of health benefits in both endogamous and exogamous couples, the correlation being strongest for disability pension. Partner correlation in disability pension receipt is slightly stronger in endogamous Swedish than in endogamous Finnish couples, while women in exogamous couples are slightly less sensitive to men’s receipt than vice versa. These findings show that the ethnic composition of couples is important for mutual health benefit receipt.
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| 13. |
- Saarela, Jan, et al.
(författare)
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‘In Sickness and in Health’: Partners’ Mutual Receipt of Sickness Allowance and Disability Pension in Present-Day Finland
- 2019
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- We study married and cohabiting partners’ mutual receipt of sickness allowance and disability pension among people aged 40-65 years in Finland in 1987-2011. Discrete-time hazard models are estimated on population-register based data that include several sociodemographic control variables. We find strong interrelations, irrespective of gender. The risk of receiving sickness allowance is approximately 50 per cent higher in the first five years after the partner’s receipt of the same benefit, while the risk of receiving disability pension is approximately 100 per cent higher in the first five years after the partner had become a disability pensioner. There are also strong dependencies across the two benefit types. Women’s risk of receiving either benefit tends to be stronger related to the male partner’s receipt than vice versa. This pattern signals that there is a caregiving effect also in the Nordic context, governed by women’s higher responsibilities for the household and the family.
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| 14. |
- Saarela, Jan, et al.
(författare)
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In sickness or in health? Register-based evidence on partners' mutual receipt of sickness allowance and disability pension
- 2019
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Ingår i: Social Science and Medicine. - : Elsevier BV. - 0277-9536 .- 1873-5347. ; 240
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Tidskriftsartikel (refereegranskat)abstract
- Studies on partners' mutual receipt of benefits constitute a growing research field in the way individual health and health-related decisions depend on social relations. This paper provides the first study on the mutual receipt of sickness allowance. We analysed married and cohabiting couples' receipt of sickness allowance and disability pension by estimating discrete-time hazard models for individuals aged 40-65 years, using longitudinal register data from Finland. The data cover the period 1987-2011, and allowed us to explore socioeconomic and demographic variables at both the individual and couple level. We found strong and long-term interrelations in receipt behaviour and dependencies across benefit types. The risk of receiving sickness allowance increases by 50 per cent during the first years after the partner's first receipt of the same benefit, while the risk of receiving disability pension is twice as high even five years after the partner's receipt of the same. Women appear to be more instrumental than men in the production of health within the couple, even in a context of high level of state support, gender equality and female labour force participation. Their receipt of disability pension is more related to the male partner's receipt than vice versa. For sickness allowance receipt, the gender asymmetry is small. Mutual benefit receipt of benefits may relate not only to collateral health effects but also to shared preferences and partner selection. We cannot distinguish between the mechanisms. However, couples with more economic and social resources seem to be more efficient in joint decision making. Correlations are particularly strong in the immediate term, and for couples who are highly educated, for those with high income, and for those with children in the household. More effective policies may be needed to equalise information regarding benefits, and monitor the use, and potential misuse, of these health benefits.
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| 15. |
- Schwarz, Emanuel, et al.
(författare)
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Analysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response
- 2018
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Ingår i: Schizophrenia Research. - Amsterdam, Netherlands : Elsevier. - 0920-9964 .- 1573-2509. ; 192, s. 398-403
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Tidskriftsartikel (refereegranskat)abstract
- The effects of gut microbiota on the central nervous system, along its possible role in mental disorders, have received increasing attention. Here we investigated differences in fecal microbiota between 28 patients with first-episode psychosis (FEP) and 16 healthy matched controls and explored whether such differences were associated with response after up to 12months of treatment. Numbers of Lactobacillus group bacteria were elevated in FEP-patients and significantly correlated with severity along different symptom domains. A subgroup of FEP patients with the strongest microbiota differences also showed poorer response after up to 12months of treatment. The present findings support the involvement of microbiota alterations in psychotic illness and may provide the basis for exploring the benefit of their modulation on treatment response and remission.
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| 16. |
- Sysi-Aho, Marko, et al.
(författare)
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Metabolic regulation in progression to autoimmune diabetes
- 2011
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Ingår i: PloS Computational Biology. - : Public Library of Science (PLoS). - 1553-734X .- 1553-7358. ; 7:10
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Tidskriftsartikel (refereegranskat)abstract
- Recent evidence from serum metabolomics indicates that specific metabolic disturbances precede β-cell autoimmunity in humans and can be used to identify those children who subsequently progress to type 1 diabetes. The mechanisms behind these disturbances are unknown. Here we show the specificity of the pre-autoimmune metabolic changes, as indicated by their conservation in a murine model of type 1 diabetes. We performed a study in non-obese prediabetic (NOD) mice which recapitulated the design of the human study and derived the metabolic states from longitudinal lipidomics data. We show that female NOD mice who later progress to autoimmune diabetes exhibit the same lipidomic pattern as prediabetic children. These metabolic changes are accompanied by enhanced glucose-stimulated insulin secretion, normoglycemia, upregulation of insulinotropic amino acids in islets, elevated plasma leptin and adiponectin, and diminished gut microbial diversity of the Clostridium leptum group. Together, the findings indicate that autoimmune diabetes is preceded by a state of increased metabolic demands on the islets resulting in elevated insulin secretion and suggest alternative metabolic related pathways as therapeutic targets to prevent diabetes.
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