| 11. |
- Moiseyenko, Volodymyr, et al.
(författare)
-
FUSION RESEARCH IN STELLARATOR DEPARTMENT OF IPP NSC KIPT
- 2022
-
Ingår i: PROBLEMS OF ATOMIC SCIENCE AND TECHNOLOGY. - : Problems of Atomic Science and Technology. - 1562-6016. ; :6, s. 3-8, s. 3-8
-
Tidskriftsartikel (refereegranskat)abstract
- This paper briefly describes intrinsic and collaborative scientific activities in the Stellarator Department of the Institute of Plasma Physics of the National Science Center "Kharkov Institute of Physics and Technology" in last two years. These activities include experiments on JET tokamak, stellarators Wendelstein 7-X and Uragan-2M, TOMAS toroidal device and theoretical studies related to modeling of radio-frequency fields in plasma and conceptual development of the stellarator-mirror fission-fusion hybrid.
|
|
| 12. |
- Fitzgerald, M., et al.
(författare)
-
Toroidal Alfven eigenmode stability in JET internal transport barrier afterglow experiments
- 2022
-
Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 62:10
-
Tidskriftsartikel (refereegranskat)abstract
- In this work, we use reduced and perturbative models to examine the stability of toroidal Alfven eigenmodes (TAEs) during the internal transport barrier (ITB) afterglow in JET experiments designed for the observation of alpha driven TAEs. We demonstrate that in JET-like conditions, it is sufficient to use an incompressible cold plasma model for the TAE to reproduce the experimental adiabatic features such as frequency and position. When ion cyclotron resonant heating (ICRH) is used to destabilize TAEs, the core-localised modes that are predicted to be most strongly driven by minority ICRH fast ions correspond to the modes observed in the DD experiments, and conversely, modes that are predicted to not be driven are not observed. Linear damping rates due to a variety of mechanisms acting during the afterglow are calculated, with important contributions coming from the neutral beam and radiative damping. For DT equivalent extrapolations of discharges without ICRH heating, we find that for the majority of modes, alpha drive is not sufficient to overcome radiative damping.
|
|
| 13. |
- Frkatović-Hodžić, Azra, et al.
(författare)
-
Mapping of the gene network that regulates glycan clock of ageing
- 2023
-
Ingår i: Aging. - 1945-4589. ; 15:24, s. 14509-14552
-
Tidskriftsartikel (refereegranskat)abstract
- Glycans are an essential structural component of immunoglobulin G (IgG) that modulate its structure and function. However, regulatory mechanisms behind this complex posttranslational modification are not well known. Previous genome-wide association studies (GWAS) identified 29 genomic regions involved in regulation of IgG glycosylation, but only a few were functionally validated. One of the key functional features of IgG glycosylation is the addition of galactose (galactosylation), a trait which was shown to be associated with ageing. We performed GWAS of IgG galactosylation (N=13,705) and identified 16 significantly associated loci, indicating that IgG galactosylation is regulated by a complex network of genes that extends beyond the galactosyltransferase enzyme that adds galactose to IgG glycans. Gene prioritization identified 37 candidate genes. Using a recently developed CRISPR/dCas9 system we manipulated gene expression of candidate genes in the in vitro IgG expression system. Upregulation of three genes, EEF1A1, MANBA and TNFRSF13B, changed the IgG glycome composition, which confirmed that these three genes are involved in IgG galactosylation in this in vitro expression system.
|
|
| 14. |
- Kazakov, Ye. O., et al.
(författare)
-
Plasma heating and generation of energetic D ions with the 3-ion ICRF + NBI scenario in mixed H-D plasmas at JET-ILW
- 2020
-
Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 60:11
-
Tidskriftsartikel (refereegranskat)abstract
- Dedicated experiments were conducted in mixed H-D plasmas in JET to demonstrate the efficiency of the 3-ion ICRF scenario for plasma heating, relying on injected fast NBI ions as the resonant ion component. Strong core localization of the RF power deposition in the close vicinity of the ion-ion hybrid layer was achieved, resulting in an efficient plasma heating, generation of energetic D ions, strong enhancement of the neutron rate and observation of Alfvenic modes. A consistent physical picture that emerged from a range of fast-ion measurements at JET, including neutron and gamma-ray measurements, a high-energy neutral particle analyzer and MHD mode localization analysis, is presented. The possibility to moderate the fast-ion energies with the ratioP(ICRF)/P(NBI)and the choice of the NBI injectors is demonstrated. An outlook of possible applications of the 3-ion scenarios, including a recent example of its use in mixed D-He-3 plasmas in JET and promising scenarios for D-T plasmas, are presented.
|
|
| 15. |
- Kiptily, V. G., et al.
(författare)
-
Excitation of Alfven eigenmodes by fusion-born alpha-particles in D-He-3 plasmas on JET
- 2022
-
Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing Ltd. - 0741-3335 .- 1361-6587. ; 64:6
-
Tidskriftsartikel (refereegranskat)abstract
- Alfven eigenmode (AE) instabilities driven by alpha-particles have been observed in D-He-3 fusion experiments on the Joint European Torus (JET) with the ITER-like wall. For the efficient generation of fusion alpha-particles from D-He-3 fusion reaction, the three-ion radio frequency scenario was used to accelerate the neutral beam injection 100 keV deuterons to higher energies in the core of mixed D-He-3 plasmas at high concentrations of He-3. A large variety of fast-ion driven magnetohydrodynamic modes were observed, including the elliptical Alfven eigenmodes (EAEs) with mode numbers n = -1 and axisymmetric modes with n = 0 in the frequency range of EAEs. The simultaneous observation of these modes indicates the presence of rather strong alpha-particle population in the plasma with a 'bump-on-tail' shaped velocity distribution. Linear stability analysis and Fokker-Planck calculations support the observations. Experimental evidence of the AEs excitation by fusion-born alpha-particles in the D-He-3 plasma is provided by neutron and gamma-ray diagnostics as well as fast-ion loss measurements. We discuss an experimental proposal for the planned full-scale D-T plasma experiments on JET based on the physics insights gained from these experiments.
|
|
| 16. |
|
|
| 17. |
- Nabais, F., et al.
(författare)
-
Bump-on-tail distributions caused by Alfvénic redistribution of energetic ions
- 2022
-
Ingår i: Nuclear Fusion. - : Institute of Physics Publishing (IOPP). - 0029-5515 .- 1741-4326. ; 62:10
-
Tidskriftsartikel (refereegranskat)abstract
- A series of experiments was performed in the JET tokamak aiming to study the characteristics and eventual effects of beam injected ion populations further accelerated through 2nd harmonic ion cyclotron heating. It was found that the injection of these ions could affect sawtooth stability and that these populations excite toroidicity induced Alfvén eigenmodes (TAEs) in the core of the plasma. More interestingly, measurements of DD beam-plasma neutrons from the TOFOR spectrometer show that these modes caused local bump-on-tail distributions in energy. Numerical simulations performed with the CASTOR-K code found a strong interaction between the core-localized TAEs and ions with energies at which local minima in the energy distribution were measured.
|
|
| 18. |
- Nocente, M., et al.
(författare)
-
Fusion product measurements by nuclear diagnostics in the Joint European Torus deuterium-tritium 2 campaign (invited)
- 2022
-
Ingår i: Review of Scientific Instruments. - : American Institute of Physics (AIP). - 0034-6748 .- 1089-7623. ; 93:9
-
Tidskriftsartikel (refereegranskat)abstract
- A new deuterium-tritium experimental, DTE2, campaign has been conducted at the Joint European Torus (JET) between August 2021 and late December 2021. Motivated by significant enhancements in the past decade at JET, such as the ITER-like wall and enhanced auxiliary heating power, the campaign achieved a new fusion energy world record and performed a broad range of fundamental experiments to inform ITER physics scenarios and operations. New capabilities in the area of fusion product measurements by nuclear diagnostics were available as a result of a decade long enhancement program. These have been tested for the first time in DTE2 and a concise overview is provided here. Confined alpha particle measurements by gamma-ray spectroscopy were successfully demonstrated, albeit with limitations at neutron rates higher than some 10(17) n/s. High resolution neutron spectroscopy measurements with the magnetic proton recoil instrument were complemented by novel data from a set of synthetic diamond detectors, which enabled studies of the supra-thermal contributions to the neutron emission. In the area of escaping fast ion diagnostics, a lost fast ion detector and a set of Faraday cups made it possible to determine information on the velocity space and poloidal distribution of the lost alpha particles for the first time. This extensive set of data provides unique information for fundamental physics studies and validation of the numerical models, which are key to inform the physics and scenarios of ITER. Published under an exclusive license by AIP Publishing.
|
|
