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Träfflista för sökning "WFRF:(Wolff M.) srt2:(2020-2024)"

Search: WFRF:(Wolff M.) > (2020-2024)

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21.	Abdel-Aziz, MI, et al. (author) A System Pharmacology Multi-Omics Approach toward Uncontrolled Pediatric Asthma 2021 In: Journal of personalized medicine. - : MDPI AG. - 2075-4426. ; 11:6 Journal article (peer-reviewed)abstract There is a clinical need to identify children with poor asthma control as early as possible, to optimize treatment and/or to find therapeutic alternatives. Here, we present the “Systems Pharmacology Approach to Uncontrolled Pediatric Asthma” (SysPharmPediA) study, which aims to establish a pediatric cohort of moderate-to-severe uncontrolled and controlled patients with asthma, to investigate pathophysiological mechanisms underlying uncontrolled moderate-to-severe asthma in children on maintenance treatment, using a multi-omics systems medicine approach. In this multicenter observational case–control study, moderate-to-severe asthmatic children (age; 6–17 years) were included from four European countries (Netherlands, Germany, Spain, and Slovenia). Subjects were classified based on asthma control and number of exacerbations. Demographics, current and past patient/family history, and clinical characteristics were collected. In addition, systems-wide omics layers, including epi(genomics), transcriptomics, microbiome, proteomics, and metabolomics were evaluated from multiple samples. In all, 145 children were included in this cohort, 91 with uncontrolled (median age = 12 years, 43% females) and 54 with controlled asthma (median age = 11.7 years, 37% females). The two groups did not show statistically significant differences in age, sex, and body mass index z-score distribution. Comprehensive information and diverse noninvasive biosampling procedures for various omics analyses will provide the opportunity to delineate underlying pathophysiological mechanisms of moderate-to-severe uncontrolled pediatric asthma. This eventually might reveal novel biomarkers, which could potentially be used for noninvasive personalized diagnostics and/or treatment.
22.	Almeida, MM, et al. (author) Blood methylome associates with fractional exhaled nitric oxide and bronchodilator drug response in pediatric asthma 2024 In: EUROPEAN JOURNAL OF HUMAN GENETICS. - 1018-4813. ; 32, s. 727-728 Conference paper (other academic/artistic)
23.	Bahmani, AHA, et al. (author) Allergic rhinitis and atopic dermatitis are associated with a decreased risk of asthma-related hospital visits in moderate to severe pediatric asthma; results of the SysPharmPediA study 2023 In: EUROPEAN RESPIRATORY JOURNAL. - 0903-1936. ; 62 Conference paper (other academic/artistic)
24.	Bahmani, AHA, et al. (author) Medication use in uncontrolled pediatric asthma: Results from the SysPharmPediA study 2023 In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. - : Elsevier BV. - 1879-0720. ; 181, s. 106360- Journal article (peer-reviewed)
25.	Bahmani, AHA, et al. (author) Medication use in uncontrolled pediatric asthma: results from the syspharmpedia study 2022 In: EUROPEAN RESPIRATORY JOURNAL. - : European Respiratory Society. - 0903-1936. ; 60 Conference paper (other academic/artistic)
26.	Jonsson, Olafur P., et al. (author) Mapping Education for Sustainability in the Nordic Countries 2021 Reports (pop. science, debate, etc.)
27.	Khamas, SS, et al. (author) Exhaled metabolite profiling for asthma control classification in children: results from the SysPharmPediA study 2023 In: EUROPEAN RESPIRATORY JOURNAL. - 0903-1936. ; 62 Conference paper (other academic/artistic)
28.	Miller, Rachael, et al. (author) Socio-ecological correlates of neophobia in corvids 2022 In: Current Biology. - : Elsevier BV. - 0960-9822. ; 32:1, s. 4-85 Journal article (peer-reviewed)abstract Behavioral responses to novelty, including fear and subsequent avoidance of novel stimuli, i.e., neophobia, determine how animals interact with their environment. Neophobia aids in navigating risk and impacts on adaptability and survival. There is variation within and between individuals and species; however, lack of large-scale, comparative studies critically limits investigation of the socio-ecological drivers of neophobia. In this study, we tested responses to novel objects and food (alongside familiar food) versus a baseline (familiar food alone) in 10 corvid species (241 subjects) across 10 labs worldwide. There were species differences in the latency to touch familiar food in the novel object and novel food conditions relative to the baseline. Four of seven socio-ecological factors influenced object neophobia: (1) use of urban habitat (versus not), (2) territorial pair versus family group sociality, (3) large versus small maximum flock size, and (4) moderate versus specialized caching (whereas range, hunting live animals, and genus did not), while only maximum flock size influenced food neophobia. We found that, overall, individuals were temporally and contextually repeatable (i.e., consistent) in their novelty responses in all conditions, indicating neophobia is a stable behavioral trait. With this study, we have established a network of corvid researchers, demonstrating potential for further collaboration to explore the evolution of cognition in corvids and other bird species. These novel findings enable us, for the first time in corvids, to identify the socio-ecological correlates of neophobia and grant insight into specific elements that drive higher neophobic responses in this avian family group. Video abstract: [Figure presented]
29.	Shahbazi Khamas, S, et al. (author) Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma: Results from the SysPharmPediA Study 2024 In: American journal of respiratory and critical care medicine. - 1535-4970. Journal article (peer-reviewed)
30.	Shapiro, RM, et al. (author) Expansion, persistence, and efficacy of donor memory-like NK cells infused for posttransplant relapse 2022 In: The Journal of clinical investigation. - 1558-8238. ; 132:11 Journal article (peer-reviewed)

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Result 21-30 of 77

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Type of publication: journal article (63); conference paper (9); research review (3); reports (1); book chapter (1)

Type of content: peer-reviewed (64); other academic/artistic (12); pop. science, debate, etc. (1)

Author/Editor: Hashimoto, S (10); Gorenjak, M (10); Harner, S (10); Brandstetter, S (10); Wolff, C (10); Pino-Yanes, M (10); show more...; Kabesch, M (10); Kraneveld, AD (10); Abdel-Aziz, MI (9); Neerincx, AH (9); Potocnik, U (9); Maitland-van Der Zee ... (9); Vijverberg, SJH (8); Almqvist, C (8); Hedman, AM (7); Korta-Murua, J (7); Sardon-Prado, O (7); Mielke, S (7); Wolff, G (7); Wolff, D (7); Toncheva, AA (6); Corcuera-Elosegui, P (6); Wolff, H (6); Brinkman, P (5); Primetzhofer, Daniel (5); Verbeek, M (5); Wolff, M. (5); Hilgendorf, I (5); Kelm, M (5); Schmidt, T. (4); Wagner, R (4); Perez-Garcia, J (4); Moldarev, Dmitrii (4); Wolff, Max (4); Jung, C. (4); Klein, S. (4); Koch, M. (4); Kobbe, G (4); Grass, S (4); Bruno, RR (4); Wernly, B (4); Lindemann, M. (4); Schafer-Eckart, K (4); Gartner, J (4); Wolschke, C (4); Teschner, D (4); Schreder, M (4); Ditschkowski, M (4); Rascle, A (4); Barabas, S (4); show less...

University: Karolinska Institutet (42); Uppsala University (12); Stockholm University (8); Lund University (8); University of Gothenburg (5); Royal Institute of Technology (5); show more...; Linköping University (5); Chalmers University of Technology (4); Malmö University (2); Umeå University (1); Örebro University (1); Stockholm School of Economics (1); RISE (1); Karlstad University (1); show less...

Language: English (77)

Research subject (UKÄ/SCB): Natural sciences (26); Medical and Health Sciences (9); Social Sciences (6); Engineering and Technology (3); Agricultural Sciences (2)

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