| 82521. |
- Kristjánsson, Sigurdur, 1955, et al.
(författare)
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Nebulised racemic adrenaline in the treatment of acute bronchiolitis in infants and toddlers.
- 1993
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Ingår i: Archives of disease in childhood. - 1468-2044. ; 69:6, s. 650-4
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Tidskriftsartikel (refereegranskat)abstract
- The effect of inhaled nebulised racemic adrenaline upon symptoms of acute bronchiolitis was investigated in 29 infants and toddlers aged 2-17.5 months by transcutaneous oxygen tension (TcPO2), oxygen saturation, transcutaneous carbon dioxide tension (TcPCO2), and clinical evaluation in a double blind placebo controlled study. Clinical score and TcPO2 improved significantly at 30, 45, and 60 minutes after inhalation of racemic adrenaline, with an increase in TcPO2 > or = 0.5 kPa in 72% of the children < 1 year of age. No significant improvement was observed after inhalation of placebo. No significant changes in heart rate or TcPCO2 were observed from before to after inhalation, but a small increase in mean systolic blood pressure was observed immediately and 45 minutes after racemic adrenaline inhalation. This study demonstrates that treatment with nebulised racemic adrenaline improved oxygenation and clinical signs in hospitalised children aged less than 18 months with bronchiolitis.
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| 82522. |
- Kristjansson, S., et al.
(författare)
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Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like response
- 2005
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Ingår i: J Allergy Clin Immunol. - : Elsevier BV. - 0091-6749. ; 116:4, s. 805-11
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Respiratory syncytial virus (RSV) infections during infancy are considered to be a risk factor for developing asthma and possibly allergic sensitization. OBJECTIVE: The aim of this study was to investigate the cytokines, chemokines, and eosinophil cationic protein in the nasopharyngeal secretions of infants < or = 7 months of age with RSV infections or other respiratory viral infections and healthy infants as controls. Groups were also analyzed according to age, < or = 3 months and >3 months, and the levels were compared within and between groups. RESULTS: Thirty-nine infants with RSV, 9 with influenza or parainfluenza virus infections and 50 controls with no history of infections, were enrolled in the study. The RSV-infected infants had significantly higher levels of IL-4; macrophage inflammatory protein 1beta, a chemoattractant for T cells; and eosinophil cationic protein in nasopharyngeal secretions compared with the control group. The levels of the TH2 cytokine IL-4 were significantly higher in RSV-infected infants < or = months of age compared with RSV-infected infants >3 months of age. In infants < or = 3 months of age, infections with influenza or parainfluenza virus caused TH2-like responses similar to those produced by RSV. CONCLUSION: Infections with RSV as well as with influenza and parainfluenza virus during early infancy preferentially promote a TH2-like response in the nose with local production of IL-4, IL-5, and macrophage inflammatory protein 1beta and infiltration and activation of eosinophils.
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| 82523. |
- Kristjansson, S., et al.
(författare)
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U-EPX levels and wheezing in infants and young children with and without RSV bronchiolitis
- 2006
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Ingår i: Respir Med. - : Elsevier BV. - 0954-6111 .- 1532-3064. ; 100:5, s. 878-83
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Tidskriftsartikel (refereegranskat)abstract
- An association between severe infant bronchiolitis due to respiratory syncytial virus (RSV) and subsequent wheezing is well documented. High levels of urinary eosinophil protein X (U-EPX) have been related to active disease in asthmatic children. The aim of this study was to analyse whether RSV bronchiolitis leads to an increase in U-EPX levels and whether wheezing is more common in children with high U-EPX values. Seventeen infants requiring in-ward care for verified RSV lower respiratory tract infection were followed and compared with age-matched controls. A reference group without a history of RSV bronchiolitis was also included. At inclusion at mean age 3.3 months and at follow-up at mean age 32.9 months, U-EPX levels were comparable in the RSV group. However, at follow-up at mean age 6.4 months, the RSV group had significantly increased levels of U-EPX compared with inclusion (median 167.8; range 46.2-470.7 vs. 122.8; 43.7-266.0 microg/mmol creatinine; P=0.023) and also significantly increased compared with the 6-month-old controls (167.8 vs. 93.0; 19.0-204.0 microg/mmol creatinine; P=0.0095). RSV infected subjects that experienced wheezing had significantly higher U-EPX values both at inclusion and at age 32.9 months than those who did not. Also, in the reference group (mean age 18.4 months), the children who had wheezed during the preceding year had higher U-EPX levels than those who had not wheezed. In conclusion, RSV bronchiolitis severe enough to require in-ward care produces a significant, but transient increase in U-EPX. Furthermore, a high U-EPX at baseline appears to be associated with an increased risk of future wheezing.
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| 82524. |
- Kristjánsson, Sigurdur, 1955, et al.
(författare)
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Urinary eosinophil protein X in children with atopic asthma: a useful marker of antiinflammatory treatment.
- 1996
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Ingår i: The Journal of allergy and clinical immunology. - 0091-6749. ; 97:6, s. 1179-87
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Tidskriftsartikel (refereegranskat)abstract
- Bronchial asthma is associated with elevated serum levels of eosinophil products, such as eosinophil protein X (EPX), but the occurrence in urine of this substance in patients with asthma has not previously been studied.This study was performed to clarify whether increased amounts of eosinophil granulocyte proteins in urine and serum reflect ongoing asthmatic inflammation and whether decreasing values reflect successful treatment.Twelve children with a median age of 12.5 years who had mild or moderate atopic asthma were studied for 3 months. At the time of inclusion in the study, treatment with inhaled budesonide was initiated. Nine children of the same age without atopic disease served as control subjects. Levels of EPX, eosinophil cationic protein (ECP), and myeloperoxidase in serum and in urine (urinary EPX) were determined at inclusion and then after 3 months of treatment. Spirometry was performed on the same occasions.At the time of inclusion, urinary EPX and serum ECP were significantly higher in children with atopic asthma than in the control subjects (mean, 116.4 vs 43.0 micrograms/mmol creatinine [p = 0.004] and 37.0 vs 14.8 micrograms/L [p = 0.004]). In the asthma group urinary EPX, as well as serum ECP, decreased significantly after 3 months of treatment with budesonide (116.4 to 68.4 micrograms/mmol creatinine [p = 0.005] and 37.0 to 24.0 micrograms/L [p = 0.04]). At the same time, peak expiratory flow values increased significantly in the children with asthma (76.0% to 87.8% of predicted value [p = 0.005]) but not in the control subjects (87.0% to 90.1%). In the asthma group the levels of myeloperoxidase were similar to those in the control group, both at inclusion and after 3 months.Increased urinary EPX and serum ECP levels seem to reflect active atopic asthma, whereas decreased levels after antiinflammatory treatment probably reflect normalization of airway inflammation, and indirectly, improved lung function.
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| 82525. |
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| 82526. |
- Kristofersson, Nils
(författare)
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Interkulturella mönstervärldar
- 2015
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Ingår i: Panncentralen, Mariestad.
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Konstnärligt arbete (övrigt vetenskapligt/konstnärligt)abstract
- En visuell undersökning av likheter och skilnader mellan kelim- och röllakanvävar som resulterat i en mängd teckningar och målningar. Undersökningens syfte var att hitta sätt att använda mig av dessa vävar som grund i egna fristående gestaltningar.
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| 82527. |
- Kristofersson, Nils
(författare)
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The function of material
- 2017
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Ingår i: 20170211-20170930 Nääs Konsthantverk, Floda (Solo exhibition) Galleri Thomassen, Gothenburg (Group exhibition) Galleri 54, Gothenburg (Group exhibition) Raum Wollreinigung, Berlin (Group exhibition) Galleri Nevven, Gothenburg (Group exhibition).
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Konstnärligt arbete (övrigt vetenskapligt/konstnärligt)abstract
- The projects has multiple points of departure: an allmost compulsive urge to adorn and decorate, an ambition to find new ways to communicate through material, a search for textile memmories and textile as social code in my own past.
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| 82528. |
- Kristofersson, Nils
(författare)
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Ultralight structures (Reconstructing umbrellas)
- 2020
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Ingår i: 2020-05-30 3:e Våningen, Göteborg 2020-10-17 Mölnlycke konsthall/ Nemeshallen, Härryda.
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Konstnärligt arbete (övrigt vetenskapligt/konstnärligt)abstract
- Utställningen innefattar 7 verk gjorda under 2018,2019 & 2020. Verken springer ur ett undersökande av paraplyers beståndsdelar och skyddande funktion, samt hur återvunna textila funktionsmaterial kan placeras i ett konstnärligt sammanhang.
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| 82529. |
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| 82530. |
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