| 1. |
- Andersch-Björkman, Ylva, et al.
(author)
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Air-oxidized linalool elicits eczema in allergic patients-a repeated open application test study.
- 2014
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In: Contact dermatitis. - : Wiley. - 1600-0536 .- 0105-1873. ; 70:3, s. 129-38
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Journal article (peer-reviewed)abstract
- Linalool is a commonly used fragrance terpene that forms potent sensitizers upon oxidation. In a recent multicentre study, we found that 7% of 2900 patients showed positive patch test reactions to oxidized linalool at 6.0%. No elicitation studies have been performed.
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| 2. |
- , Anonymous]
(author)
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Governance, stewardship and cosmetics
- 2014
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In: Contact dermatitis. - : Wiley. - 1600-0536 .- 0105-1873. ; 70:5, s. 261-261
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Journal article (other academic/artistic)
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| 3. |
- , Anonymous]
(author)
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Myths, beliefs and fragrance allergy
- 2013
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In: Contact dermatitis. - : Wiley. - 1600-0536 .- 0105-1873. ; 69:4, s. 193-195
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Journal article (other academic/artistic)
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| 4. |
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| 5. |
- Bergendorff, O., et al.
(author)
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A method for assessment of exposure to rubber glove allergens
- 2012
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In: Contact Dermatitis. - : Wiley. - 0105-1873. ; 66:s2, s. 70-71
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Conference paper (other academic/artistic)abstract
- Background: Use of disposable protective gloves in health care is necessary both to protect patients and personnel. However, the use might also be responsible for skin disease among persons wearing the gloves. Dermatitis may be caused by additives in the gloves, either from manufacturing of the glove material or components in coatings applied after vulcanization. Objectives: We wanted to analyse to what extent chemicals were deposited to skin from the glove and to compare these results with analysis of the glove itself. Methods: After usage of protective gloves, the hands are washed with an ethanolic water solution in a plastic bag for 1 min. The wash solution is then analysed by different HPLC-methods to determine how much of each rubber allergen that has been left on the skin surface. Similar gloves are analysed by traditional methods by extraction with organic solvents to see which rubber allergens that are present in the glove. Results: Two different HPLC-methods were then chosen for analysis of the wash solution. Firstly a cyano-column was used for analysis of basic analytes like cetylpyridinium chloride and diphenylguanidine and secondly a nickel salt derivatisation stepwas used to stabilise dithiocarbamates for analysis on a C18 column. In the latter system thiurams and mercaptobenzothiazoles were analysed simultaneously. Conclusions: By this mild and non-invasive method we could analyse dermal exposure to the most important allergens in rubber gloves. The method enables us to assess how for example different working procedures before and during the use of protective gloves will influence on the amounts of chemicals that are deposited on the skin from different gloves.
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| 8. |
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| 9. |
- Björk, Ann-Kristin, et al.
(author)
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Occupational allergic contact dermatitis to gloves, follow-up of investigated patients
- 2014
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In: Contact Dermatitis. - : Wiley. - 0105-1873. ; 70:Suppl s1, s. 94-94
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Conference paper (other academic/artistic)abstract
- Background: In the Department of Occupational and Environmental Dermatology there has been an increase in the inflow of patients, working as surgical nurses or surgeons. They have been referred due to presumed occupational contact dermatitis. Results from investigated patients have in part been presented previously, where the investigation has shownmultiple contact allergies caused by their occupational use of gloves. Allergens such as diphenylguanidine were found in the gloves and contact allergies to their rubber gloves were found. Many of the patients have been working for decades in their present occupation, but the hand dermatitis had often been present for less than a year. Objectives: To present a follow-up of patientswith hand dermatitis due to gloves. Methods: A follow-up of the patients and a structure for the investigation of the individual patient are given. Results: The cases will be presented with their contact allergies, howtheinvestigation isperformedandtheoutcomeof theprevention by avoiding gloves containing the allergens diagnosed in the individual patients. Conclusions: For health care personnel hand hygiene and the wearing of protective gloves are mandatory. Our findings indicate that the increased need to use rubber gloves and at the same time the exclusion of latex gloves give rise to new contact allergies which are clinically relevant. In the investigation, and the advice given to the patients, several factors have to be taken into consideration, including the fast change of glove material. The cases indicate the importance of close cooperation between chemists and dermatologists and the possibility to perform chemical analysis. Furthermore, and just as important for this patient group, is that with correct diagnosis and advice the contact dermatitis can actually heal completely and the patients continue in their work.
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| 10. |
- Bruze, Magnus, et al.
(author)
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A positive cobalt spot test falsely indicating an occupational allergic contact dermatitis caused by cobalt.
- 2013
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In: Contact Dermatitis. - : Wiley. - 0105-1873. ; 69:3, s. 172-175
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Journal article (peer-reviewed)abstract
- For investigation of chemical exposure in allergic individuals, spot tests are invaluable. A reagent may react with a specific compound to give a specific typical colour, and thus indicate the presence of the specific substance. Spot tests can give both false-negative and false-positive reactions. To confirm the presence of the substance and quantify it, more sophisticated methods are required. On the basis of a positive cobalt spot test result, a woman was initially diagnosed with an occupational allergic contact dermatitis caused by cobalt.
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