| 1. |
- Ödkvist, L., et al.
(författare)
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The role of osturography and ENG in whiplash injuries
- 1995
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Ingår i: Vertigo, nausea, tinnitus, and hearing loss in central and peripheral vestibular diseases. - Amsterdam : Elsevier. - 9780444821935 ; , s. 259-262
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Konferensbidrag (refereegranskat)
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| 2. |
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| 3. |
- Niklasson, M., et al.
(författare)
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Are deficits in the equilibrium system relevant to the clinical investigation of solvent-induced neurotoxicity?
- 1997
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Ingår i: Scandinavian Journal of Work, Environment and Health. - 0355-3140 .- 1795-990X. ; 23:3, s. 206-213
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The diagnosis of solvent-induced chronic toxic encephalopathy is commonly based on case histories of exposure to solvents, symptoms, and deficits on psychometric tests. It has previously been demonstrated that long-term solvent-exposed workers have disturbances of the equilibrium system. The correlation between these disturbances and the diagnosis of chronic toxic encephalopathy has been analyzed in the present study. MATERIAL AND METHODS: Sixty men, consecutively admitted due to the suspicion of this syndrome, were investigated and classified into 3 groups--solvent-induced chronic toxic encephalopathy, incipient chronic toxic encephalopathy and nonchronic toxic encephalopathy. They were all examined using an otoneurological test battery, including analysis of saccades, smooth pursuit, visual suppression of the vestibular ocular reflex, and dynamic posturography. RESULTS: Compared with healthy referents several of the subjects, even in the nonchronic toxic encephalopathy group, showed a reduced visual suppression ability, a prolonged latency of saccades, and pathological posturographic results. Some otoneurological tests correlated with the duration of exposure and the results of psychometric tests representing memory and perceptual skills. Nevertheless, there was no significant group correlation between the otoneurological findings and the diagnosis of chronic toxic encephalopathy. CONCLUSION: Disturbances revealed by an otoneurological investigation have so far not been considered in the diagnosis of chronic toxic encephalopathy. Our results indicate that an otoneurological test battery adds worthwhile information about lesions within the brainstem-cerebellar complex not revealed by a psychometric investigation.
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| 4. |
- Thoumas, K.-Å., et al.
(författare)
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MR imaging in solvent-induced chronic toxic encephalopathy
- 1996
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Ingår i: Acta Radiologica. - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 37:2, s. 177-179
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To use MR to examine patients with CNS symptoms indicating chronic intoxication. Material and Methods: Thirty-two subjects exposed to industrial solvents for 5 to 28 years and 40 age-matched, healthy controls were examined. Results: All patients showed decreased signal in the basal ganglia on T2-weighted images. In 11 of the patients the white matter showed diffuse hyperintensity with loss of the grey-white matter discrimination and with distinct periventricular hyperintensities in 5 of the patients. The controls had no pathological changes in the brain. Conclusion: Although the relatively small number of patients may obscure the significance, findings observed on T2-weighted images were patchy periventricular hyperintensities and hypointensities in the basal ganglia. Fast spin-echo is a good technique with fast acquisition of images with true spin-echo contrast features.
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| 5. |
- Ödkvist, L. M., et al.
(författare)
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When and how to use Gentamicin in the treatment of Meniere's disease
- 1997
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Ingår i: Acta oto-laryngologica. Supplementum. - : Informa UK Limited. - 0365-5237 .- 1651-2464 .- 0001-6489 .- 1651-2251. ; 117:S526, s. 54-57
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Tidskriftsartikel (refereegranskat)abstract
- Gentamicin given as local therapy for severe Meniere's disease is of considerable value in the control of vertigo. The ototoxic antibiotic is instilled through the tympanic membrane causing a peripheral vestibular loss and possibly also diminished endolymph production. In order to achieve the best results with gentamicin treatment it is of utmost importance that the diagnosis is correct. Given to a patient with vertigo of other than peripheral origin, the outcome would be worsening of the existing symptoms and addition of new ones. The method should be used only by physicians who are very familiar with vertigo and otology, and only in patients with such a disturbing degree of vertigo that they are well motivated to receive treatment. Thorough information regarding the disease, the treatment procedure and the symptoms caused by a unilateral peripheral vestibular loss should be given to the patient. Vestibular rehabilitation, including movement therapy, should be given by the physician or, preferably, a well trained physiotherapist on an individual basis or in patient groups together with written practice programmes for use at home. Vertigo attacks are usually relieved in 95% of patients. Twenty percent of patients experience an added hearing loss in the treated ear, although this number is reduced if the treatment is given as a single installment on consecutive days with extra installments given one month later if the vertigo remains.
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