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- Thuring, Ann, et al.
(författare)
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Doppler Audio Signal Analysis as an Additional Tool in Evaluation of Umbilical Artery Circulation
- 2017
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Ingår i: Ultraschall in der Medizin. - : Georg Thieme Verlag KG. - 1438-8782. ; 38:5, s. 549-555
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To investigate the predictive capacity of a new method for sound spectrum analysis of Doppler signals recorded from the umbilical artery in high-risk pregnancies. Material and Methods: The retrospective study comprised 127 pregnant women with various pregnancy complications between 23 and 39 gestational weeks. Umbilical artery blood flow velocity waveforms were recorded with Doppler ultrasound and characterized by pulsatility index (PI) and blood flow class (BFC). Doppler audio signals were stored on a digital video recorder and the sound frequency at the energy level 15 dB below its peak (MAXpeak-15 dB) was estimated off-line. The prediction of probability for composite adverse pregnancy outcome (operative delivery for fetal distress, admission to neonatal intensive care unit, perinatal death) was evaluated using the area under the curve (AUC) of the receiver operating characteristics (ROC) curve. Results: With increasing umbilical artery BFC, the MAXpeak-15 dB frequencies decreased (p < 0.0001) and the PI increased (p < 0.0001). The ROC AUCs for adverse outcome for MAXpeak-15 dB and for PI were 0.842 and 0.836 (p = 0.88), respectively. For the combination of MAXpeak-15 dB and PI, the corresponding AUC was 0.894, significantly higher than that of PI (p < 0.03) and of MAXpeak-15 dB (p < 0.05). Conclusion: Umbilical artery Doppler sound spectrum analysis might be a useful supplement to PI in the clinical evaluation of fetoplacental circulation.
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- Chen, Ting-Wan, 1984-
(författare)
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SN 2021gno : a calcium-rich transient with double-peaked light curves
- 2023
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Ingår i: Monthly notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 526:1, s. 279-298
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Tidskriftsartikel (refereegranskat)abstract
- We present extensive ultraviolet (UV) and optical photometric and optical spectroscopic follow-up of supernova (SN) 2021gno by the ‘Precision Observations of Infant Supernova Explosions’ (POISE) project, starting less than 2 d after the explosion. Given its intermediate luminosity, fast photometric evolution, and quick transition to the nebular phase with spectra dominated by [Ca II] lines, SN 2021gno belongs to the small family of Calcium-rich transients. Moreover, it shows double-peaked light curves, a phenomenon shared with only four other Calcium-rich events. The projected distance from the centre of the host galaxy is not as large as other objects in this family. The initial optical light-curve peaks coincide with a very quick decline of the UV flux, indicating a fast initial cooling phase. Through hydrodynamical modelling of the bolometric light curve and line velocity evolution, we found that the observations are compatible with the explosion of a highly stripped massive star with an ejecta mass of 0.8 M⊙ and a 56Ni mass of 0.024 M⊙. The initial cooling phase (first light-curve peak) is explained by the presence of an extended circumstellar material comprising ∼10−2 M⊙ with an extension of 1100 R⊙. We discuss if hydrogen features are present in both maximum-light and nebular spectra, and their implications in terms of the proposed progenitor scenarios for Calcium-rich transients.
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5. |
- Gendre, Delphine, et al.
(författare)
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Conserved Arabidopsis ECHIDNA protein mediates trans-Golgi-network trafficking and cell elongation
- 2011
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 108:19, s. 8048-8053
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Tidskriftsartikel (refereegranskat)abstract
- Multiple steps of plant growth and development rely on rapid cell elongation during which secretory and endocytic trafficking via the trans-Golgi network (TGN) plays a central role. Here, we identify the ECHIDNA (ECH) protein from Arabidopsis thaliana as a TGN-localized component crucial for TGN function. ECH partially complements loss of budding yeast TVP23 function and a Populus ECH complements the Arabidopsis ech mutant, suggesting functional conservation of the genes. Compared with wild-type, the Arabidopsis ech mutant exhibits severely perturbed cell elongation as well as defects in TGN structure and function, manifested by the reduced association between Golgi bodies and TGN as well as mislocalization of several TGN-localized proteins including vacuolar H(+)-ATPase subunit a1 (VHA-a1). Strikingly, ech is defective in secretory trafficking, whereas endocytosis appears unaffected in the mutant. Some aspects of the ech mutant phenotype can be phenocopied by treatment with a specific inhibitor of vacuolar H(+)-ATPases, concanamycin A, indicating that mislocalization of VHA-a1 may account for part of the defects in ech. Hence, ECH is an evolutionarily conserved component of the TGN with a central role in TGN structure and function.
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6. |
- Hamilton, D. S., et al.
(författare)
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Reassessment of pre-industrial fire emissions strongly affects anthropogenic aerosol forcing
- 2018
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1
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Tidskriftsartikel (refereegranskat)abstract
- Uncertainty in pre-industrial natural aerosol emissions is a major component of the overall uncertainty in the radiative forcing of climate. Improved characterisation of natural emissions and their radiative effects can therefore increase the accuracy of global climate model projections. Here we show that revised assumptions about pre-industrial fire activity result in significantly increased aerosol concentrations in the pre-industrial atmosphere. Revised global model simulations predict a 35% reduction in the calculated global mean cloud albedo forcing over the Industrial Era (1750–2000 CE) compared to estimates using emissions data from the Sixth Coupled Model Intercomparison Project. An estimated upper limit to pre-industrial fire emissions results in a much greater (91%) reduction in forcing. When compared to 26 other uncertain parameters or inputs in our model, pre-industrial fire emissions are by far the single largest source of uncertainty in pre-industrial aerosol concentrations, and hence in our understanding of the magnitude of the historical radiative forcing due to anthropogenic aerosol emissions.
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- Landqvist, Hans, 1958, et al.
(författare)
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Intresse och engagemang: Kungliga Tekniska högskolans insatser i ett svenskt terminologiskt nätverk 1941–1983 : Interest and involvement: the contributions of the Royal Institute of Technology to a Swedish terminological network 1941–1983
- 2021
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Ingår i: Folkmålsstudier Meddelanden från Föreningen för nordisk filologi. - 0356-1771. ; 59, s. 103-133
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, we study how KTH Royal Institute of Technology (Kungliga Tekniska högskolan – KTH) has participated in and influenced terminology work coordinated by the national terminology centre, the Swedish Centre for Technical Terminology – the TNC, in Sweden during the period 1941–1983. The aim of this paper is to shed light on the development of Swedish (technical) terminology based on networking and experts’ efforts. Based on archive material, we analyze who have been the active KTH experts, in what ways they were involved in the development processes and what effects their efforts had on the term recommendations given by the TNC. The archive material consists of written documents relating to the work process developed by John Wennerberg, who led the TNC between 1941 and 1957. The process was carried out in the form of 373 formal survey letters representing 17 subject fields, with both the TNC and external parties participating. Our results show that the 31 identified KTH experts play a visible role in the processes by 480 received survey letters within 14 subject fields. The response rate, 80 percent, reveal the experts’ involvement in the process and their high esteem of TNC’s work. The analysis of the comprehensive survey letter R198 shows that Wennerberg has considered the experts’ answers regarding terms (selection, linguistic form, acceptance/discourage) and definitions when he has published TNC’s recommendations. Our study shows that networking and experts representing the educational sector and furthermore universities have been an inseparable part of the development of Swedish (technical) terminology during several decades when the national terminology centre in Sweden began to operate and the working methods were established.
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- Pino Rodríguez, Aymé, 1961-
(författare)
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Un estudio contrastivo basado en corpus del uso del conector entonces/då por aprendices suecos de español como lengua extranjera
- 2014
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Ingår i: Nordic Romanist Congress, Iceland, August 12-15, 2014.
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Konferensbidrag (refereegranskat)abstract
- La presente comunicación describe y analiza el uso y frecuencia del conector entonces/då en 135 textos producidos por 45 aprendices suecos de español como lengua extranjera, de nivel de conocimiento A2-B1 según la escala del Marco Común Europeo de Referencia para las Lenguas (MCERL). Los resultados obtenidos se comparan con un número similar de textos extraídos de dos corpus de control: un corpus de hispanohablantes (corpus de control de hispanohablantes- CEDEL2) y otro de nativos suecos (corpus de control suecos- ARGUS). El estudio aporta nuevos conocimientos acerca de las características de la interlengua de nativos suecos en el referido nivel de aprendizaje. Los textos argumentativos forman parte del Corpus denominado SAELE (Suecos aprendices de español como lengua extranjera), una compilación de textos electrónicos de lengua escrita de aprendices de lengua extranjera.
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10. |
- Thuring, Ann, et al.
(författare)
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Audio spectrum analysis of umbilical artery Doppler ultrasound signals applied to a clinical material.
- 2014
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 1600-0412 .- 0001-6349. ; 93:12, s. 1320-1324
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Tidskriftsartikel (refereegranskat)abstract
- Analysis of umbilical artery flow velocity waveforms characterized by pulsatility index (PI) is used to evaluate fetoplacental circulation in high-risk pregnancies. However, an experienced sonographer may be able to further differentiate between various timbres of Doppler audio signals. Recently, we have developed a method for objective audio signal characterization; the method has been tested in an animal model. In the present pilot study, the method was for the first time applied to human pregnancies. Doppler umbilical artery velocimetry was performed in 13 preterm fetuses before and after two doses of 12 mg betamethasone. The auditory measure defined by the frequency band where the spectral energy had dropped 15 dB from its maximum level (MAXpeak-15 dB ), increased two days after betamethasone administration (p = 0.001) parallel with a less pronounced decrease in PI (p = 0.04). The new auditory parameter MAXpeak-15 dB reflected the changes more sensitively than the PI did.
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