| 1. |
- Beech, Jason P., et al.
(författare)
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Capillary driven separation on patterned surfaces
- 2009
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Ingår i: Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. - 9780979806421 ; , s. 785-787
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Konferensbidrag (refereegranskat)abstract
- Deterministic lateral displacement (DLD) is a powerful bimodal separation scheme [1] based on fluid flow through regular obstacle arrays that in its basic embodiment sends suspended particles in two different directions as a function of size. We show that without the need to seal devices and without the need for fluidic connections or pumps, particle separation can be achieved by the passive flow of a sample over a patterned surface. Risk of clogging is minimized by the movement of large particles above the obstacle array. Suitable application areas include blood fractionation and analysis of drinking water. 0
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| 2. |
- Beech, Jason P., et al.
(författare)
-
Gravitationally driven deterministic lateral displacement devices
- 2009
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Ingår i: Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. - 9780979806421 ; , s. 779-781
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Konferensbidrag (refereegranskat)abstract
- Deterministic lateral displacement (DLD) is a powerful bimodal separation scheme [1] based on regular obstacle arrays that in its basic embodiment sends particles in two different directions as a function of size. We add functionality to the technique by including gravitational forces, as a perturbation to particles transported by fluid flow, and as a way of transporting the particles through a stationary fluid.
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| 3. |
- Beech, Jason P., et al.
(författare)
-
Shape-based particle sorting - A new paradigm in microfluidics
- 2009
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Ingår i: Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. - 9780979806421 ; , s. 800-802
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Konferensbidrag (refereegranskat)abstract
- Conventional fractionation techniques fail to fully benefit from the variety in morphology and shape that is found among biological particles. Although light scattering in conventional FACS gives some information on the size and morphology of a particle, it is generally not capable of giving a definite number on specified dimensions of a small object. We demonstrate an approach where we select which dimension of a particular object is used to determine its trajectory through an obstacle course and thereby sort not merely with respect to hydrodynamic radius but rather with respect to e.g. thickness, length or width.
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