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Träfflista för sökning "(WFRF:(Biasini M)) srt2:(2020-2023)"

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Enumeration	Reference	Cover	Find
1.	2021 swepub:Mat__t
2.	Glasbey, JC, et al. (author) 2021 swepub:Mat__t
3.	Tabiri, S, et al. (author) 2021 swepub:Mat__t
4.	Bravo, L, et al. (author) 2021 swepub:Mat__t
5.	Glasbey, JC, et al. (author) Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study 2021 In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. - : American Society of Clinical Oncology. - 1527-7755 .- 0732-183X. ; 39:1, s. 66- Journal article (peer-reviewed)
6.	Yu, Tiangxiong, et al. (author) A-MYB/TCFL5 regulatory architecture ensures the production of pachytene piRNAs in placental mammals 2023 In: RNA. - : Cold Spring Harbor Laboratory. - 1355-8382 .- 1469-9001. ; 29:1, s. 30-43 Journal article (peer-reviewed)abstract In male mice, the transcription factor A-MYB initiates the transcription of pachytene piRNA genes during meiosis. Here, we report that A-MYB activates the transcription factor Tcfl5 produced in pachytene spermatocytes. Subsequently, A-MYB and TCFL5 reciprocally reinforce their own transcription to establish a positive feedback circuit that triggers pachytene piRNA production. TCFL5 regulates the expression of genes required for piRNA maturation and promotes transcription of evolutionarily young pachytene piRNA genes, whereas A-MYB activates the transcription of older pachytene piRNA genes. Intriguingly, pachytene piRNAs from TCFL5-dependent young loci initiate the production of piRNAs from A-MYB-dependent older loci, ensuring the self-propagation of pachytene piRNAs. A-MYB and TCFL5 act via a set of incoherent feedforward loops that drive regulation of gene expression by pachytene piRNAs during spermatogenesis. This regulatory architecture is conserved in rhesus macaque, suggesting that it was present in the last common ancestor of placental mammals.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Negri, G. (5); Qureshi, A. (5); Romano, M. (5); Morton, A. (5); Bertoli, G (5); Martin, J. (5); show more...; Lakkis, Z (5); Rottoli, M (5); Moore, R. (5); Giraudo, G. (5); Sharma, N. (5); Grassi, T. (5); Tuveri, M. (5); Nowak, K. (5); O'Brien, S. (5); Roberts, M. (5); Abate, E. (5); Santoro, A (5); Negoi, I (5); Salem, H (5); Desai, A. (5); Conti, L. (5); Serra, M. (5); Sherif, A. (5); Fleming, C (5); Mathieu, P (5); Khan, T. (5); Smith, J. (5); Tiwari, A (5); Cox, D (5); Vitali, A (5); Muiesan, P (5); Adamina, M (5); Emile, S (5); Ghosh, D (5); Lawday, S (5); Li, E (5); Modolo, MM (5); Mohan, HM (5); Pata, F (5); Pockney, P (5); Dawson, BE (5); Evans, JP (5); Jones, CS (5); Khatri, C (5); Gallo, G (5); Roberts, K (5); Satoi, S (5); Edwards, J (5); Layton, GR (5); show less...

University: Karolinska Institutet (4); Umeå University (1); Uppsala University (1); Stockholm University (1)

Language: English (6)

Research subject (UKÄ/SCB): Natural sciences (1); Medical and Health Sciences (1)

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