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A Novel Approach to...
A Novel Approach to Hematology Testing at the Point of Care
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- Bransky, Avishay (författare)
- PixCell Medical Technologies Ltd., Yokneam Ilit, Israel.,PixCell Med Technol Ltd, Israel
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- Larsson, Anders (författare)
- Uppsala universitet,Klinisk kemi,Uppsala Univ, Sweden
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- Aardal, Elisabeth (författare)
- Linköpings universitet,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, Klinisk kemi
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- Ben-Yosef, Yaara (författare)
- PixCell Medical Technologies Ltd., Yokneam Ilit, Israel.,PixCell Med Technol Ltd, Israel
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- Christenson, Robert H (författare)
- University of Maryland School of Medicine Baltimore, MD.,Univ Maryland, MD 21201 USA
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PixCell Medical Technologies Ltd, Yokneam Ilit, Israel. PixCell Med Technol Ltd, Israel (creator_code:org_t)
- 2020-12-04
- 2021
- Engelska.
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Ingår i: The journal of applied laboratory medicine. - : Oxford University Press (OUP). - 2576-9456 .- 2475-7241. ; 6:2, s. 532-542
- Relaterad länk:
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https://europepmc.or...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The need for rapid point-of-care (POC) diagnostics is now becoming more evident due to the increasing need for timely results and improvement in healthcare service. With the recent COVID-19 pandemic outbreak, POC has become critical in managing the spread of disease. Applicable diagnostics should be readily deployable, easy to use, portable, and accurate so that they fit mobile laboratories, pop-up treatment centers, field hospitals, secluded wards within hospitals, or remote regions, and can be operated by staff with minimal training. Complete blood count (CBC), however, has not been available at the POC in a simple-to-use device until recently. The HemoScreen, which was recently cleared by the FDA for POC use, is a miniature, easy-to-use instrument that uses disposable cartridges and may fill this gap.CONTENT: The HemoScreen's analysis method, in contrast to standard laboratory analyzers, is based on machine vision (image-based analysis) and artificial intelligence (AI). We discuss the different methods currently used and compare their results to the vision-based one. The HemoScreen is found to correlate well to laser and impedance-based methods while emphasis is given to mean cell volume (MCV), mean cell hemoglobin (MCH), and platelets (PLT) that demonstrate better correlation when the vision-based method is compared to itself due to the essential differences between the underlying technologies.SUMMARY: The HemoScreen analyzer demonstrates lab equivalent performance, tested at different clinical settings and sample characteristics, and might outperform standard techniques in the presence of certain interferences. This new approach to hematology testing has great potential to improve quality of care in a variety of settings.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
Nyckelord
- CBC
- analyzer
- hematology
- image analysis
- point of care
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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