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- Soucek, J., et al.
(författare)
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EMC Aspects Of Turbulence Heating Observer (THOR) Spacecraft
- 2016
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Ingår i: Proceedings Of 2016 Esa Workshop On Aerospace Emc (Aerospace Emc). - : Institute of Electrical and Electronics Engineers (IEEE). - 9789292213039
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Konferensbidrag (refereegranskat)abstract
- Turbulence Heating ObserveR (THOR) is a spacecraft mission dedicated to the study of plasma turbulence in near-Earth space. The mission is currently under study for implementation as a part of ESA Cosmic Vision program. THOR will involve a single spinning spacecraft equipped with state of the art instruments capable of sensitive measurements of electromagnetic fields and plasma particles. The sensitive electric and magnetic field measurements require that the spacecraft-generated emissions are restricted and strictly controlled; therefore a comprehensive EMC program has been put in place already during the study phase. The THOR study team and a dedicated EMC working group are formulating the mission EMC requirements already in the earliest phase of the project to avoid later delays and cost increases related to EMC. This article introduces the THOR mission and reviews the current state of its EMC requirements.
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| 4. |
- Calati, R, et al.
(författare)
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Cancer and suicidal ideation and behaviours: protocol for a systematic review and meta-analysis
- 2018
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 8:8, s. e020463-
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Tidskriftsartikel (refereegranskat)abstract
- Prevalence of suicidal ideation (SI) and behaviours are higher among patients with cancer than general population. No systematic review/meta-analysis investigated this topic; therefore, our aim will be to assess the relationship between cancer and SI and behaviours.MethodsWe will search PubMed/MEDLINE, EMBASE, SCOPUS, Web of Science, PsycINFO and Cochrane Library databases from their inception until 30 June 2018. Case–control and cohort studies focused on the association between cancer (any type) and suicidal outcomes (suicide, suicide attempt and SI) will be included. Two team members will independently: (A) perform the selection of the included studies and data extraction, with the supervision of a third member in case of discrepancies and (B) assess each study with: (1) Newcastle-Ottawa Scale (NOS); (2) Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement; (3) Grading of Recommendations Assessment, Development and Evaluation (GRADE). We will conduct a random-effects meta-analysis. Individual and pooled ORs and associated 95% CIs will be calculated as well as between-study heterogeneity. We will examine the potential for publication bias. If possible, we will explore reasons for potential between-study heterogeneity.Ethics and disseminationThis study does not require ethical approval. The study will be submitted to a peer-reviewed journal, will be publicly disseminated and will be the topic of research presentations.PROSPERO registration numberCRD42017072482.
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| 6. |
- Mastinu, Enzo, 1987, et al.
(författare)
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Grip control and motor coordination with implanted and surface electrodes while grasping with an osseointegrated prosthetic hand
- 2019
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Ingår i: Journal of Neuroengineering and Rehabilitation. - : Springer Science and Business Media LLC. - 1743-0003. ; 16:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: Replacement of a lost limb by an artificial substitute is not yet ideal. Resolution and coordination of motor control approximating that of a biological limb could dramatically improve the functionality of prosthetic devices, and thus reduce the gap towards a suitable limb replacement. Methods: In this study, we investigated the control resolution and coordination exhibited by subjects with transhumeral amputation who were implanted with epimysial electrodes and an osseointegrated interface that provides bidirectional communication in addition to skeletal attachment (e-OPRA Implant System). We assessed control resolution and coordination in the context of routine and delicate grasping using the Pick and Lift and the Virtual Eggs Tests. Performance when utilizing implanted electrodes was compared with the standard-of-care technology for myoelectric prostheses, namely surface electrodes. Results: Results showed that implanted electrodes provide superior controllability over the prosthetic terminal device compared to conventional surface electrodes. Significant improvements were found in the control of the grip force and its reliability during object transfer. However, these improvements failed to increase motor coordination, and surprisingly decreased the temporal correlation between grip and load forces observed with surface electrodes. We found that despite being more functional and reliable, prosthetic control via implanted electrodes still depended highly on visual feedback. Conclusions: Our findings indicate that incidental sensory feedback (visual, auditory, and osseoperceptive in this case) is insufficient for restoring natural grasp behavior in amputees, and support the idea that supplemental tactile sensory feedback is needed to learn and maintain the motor tasks internal model, which could ultimately restore natural grasp behavior in subjects using prosthetic hands. © 2019 The Author(s).
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| 7. |
- Nakamura, R., et al.
(författare)
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Initial Results From the Active Spacecraft Potential Control Onboard Magnetospheric Multiscale Mission
- 2017
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Ingår i: IEEE Transactions on Plasma Science. - : Institute of Electrical and Electronics Engineers (IEEE). - 0093-3813 .- 1939-9375. ; 45:8, s. 1847-1852
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Tidskriftsartikel (refereegranskat)abstract
- NASA's magnetospheric multiscale (MMS) mission was successfully launched in March 2015. The scientific objectives of MMS are to explore and understand fundamental plasma physics processes in the earth's magnetosphere: magnetic reconnection, particle acceleration, and turbulence. The region of scientific interest of MMS is in a tenuous plasma environment where the positive spacecraft potential may reach an equilibrium as high as several tens of volts. The active spacecraft potential control (ASPOC) instrument neutralizes the spacecraft potential by releasing the positive charge produced by indium ion emitters. While the method has successfully been applied to other spacecraft such as Cluster and Double Star, new developments in the design of the emitters and the electronics are enabling lower spacecraft potentials and higher reliability compared to previous missions. In this paper, we report the initial results from the tests of the ASPOC performance during the commissioning phase and discuss the different effects on the particle and field instruments observed at different plasma environments in the magnetosphere.
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| 9. |
- Toledo-Redondo, S., et al.
(författare)
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Electrostatic Spacecraft Potential Structure and Wake Formation Effects for Characterization of Cold Ion Beams in the Earth's Magnetosphere
- 2019
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Ingår i: Journal of Geophysical Research - Space Physics. - : Blackwell Publishing Ltd. - 2169-9380 .- 2169-9402. ; 124:12, s. 10048-10062
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Tidskriftsartikel (refereegranskat)abstract
- Cold plasma (up to few tens of electron volts) of ionospheric origin is present most of the time, in most of the regions of the Earth's magnetosphere. However, characterizing it using in situ measurements is difficult, owing to spacecraft electrostatic charging, as often this charging is at levels comparable to or even higher than the equivalent energy of the cold plasma. To overcome this difficulty, active potential control devices are usually placed on spacecraft that artificially reduce spacecraft charging. The electrostatic potential structure around the spacecraft is often assumed to be spherically symmetric, and corrections are applied to the measured particle distribution functions. In this work, we show that large deviations from the spherical model are present, owing to the presence of long electric field booms. We show examples using Magnetospheric MultiScale spacecraft measurements of the electrostatic potential structure and its effect on the measurement of cold ion beams. Overall, we find that particle detectors underestimate the cold ion density under certain conditions, even when their bulk kinetic energy exceeds the equivalent spacecraft potential energy and the ion beam reaches the spacecraft. Active potential control helps in reducing this unwanted effect, but we show one event with large cold ion density (∼10 cm−3) where particle detectors provide density estimates a factor of 3–5 below the density estimated from the plasma frequency. Understanding these wake effects indirectly constrains some properties of the magnetospheric cold ion component, such as their drift energy, direction, and temperature.
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| 10. |
- van Hilst, Jony, et al.
(författare)
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Minimally Invasive versus Open Distal Pancreatectomy for Ductal Adenocarcinoma (DIPLOMA)
- 2019
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Ingår i: Annals of Surgery. - : Lippincott Williams & Wilkins. - 0003-4932 .- 1528-1140. ; 269:1, s. 10-17
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this study was to compare oncological outcomes after minimally invasive distal pancreatectomy (MIDP) with open distal pancreatectomy (ODP) in patients with pancreatic ductal adenocarcinoma (PDAC).Background: Cohort studies have suggested superior short-term outcomes of MIDP vs. ODP. Recent international surveys, however, revealed that surgeons have concerns about the oncological outcomes of MIDP for PDAC.Methods: This is a pan-European propensity score matched study including patients who underwent MIDP (laparoscopic or robot-assisted) or ODP for PDAC between January 1, 2007 and July 1, 2015. MIDP patients were matched to ODP patients in a 1:1 ratio. Main outcomes were radical (R0) resection, lymph node retrieval, and survival.Results: In total, 1212 patients were included from 34 centers in 11 countries. Of 356 (29%) MIDP patients, 340 could be matched. After matching, the MIDP conversion rate was 19% (n = 62). Median blood loss [200 mL (60–400) vs 300 mL (150–500), P = 0.001] and hospital stay [8 (6–12) vs 9 (7–14) days, P < 0.001] were lower after MIDP. Clavien-Dindo grade ≥3 complications (18% vs 21%, P = 0.431) and 90-day mortality (2% vs 3%, P > 0.99) were comparable for MIDP and ODP, respectively. R0 resection rate was higher (67% vs 58%, P = 0.019), whereas Gerota's fascia resection (31% vs 60%, P < 0.001) and lymph node retrieval [14 (8–22) vs 22 (14–31), P< 0.001] were lower after MIDP. Median overall survival was 28 [95% confidence interval (CI), 22–34] versus 31 (95% CI, 26–36) months (P = 0.929).Conclusions: Comparable survival was seen after MIDP and ODP for PDAC, but the opposing differences in R0 resection rate, resection of Gerota's fascia, and lymph node retrieval strengthen the need for a randomized trial to confirm the oncological safety of MIDP.
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