| 1. |
- Anderson, Maria, et al.
(författare)
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Oral microflora in preschool children attending a fluoride varnish program: a cross-sectional study.
- 2016
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Ingår i: BMC oral health. - : Springer Science and Business Media LLC. - 1472-6831. ; 16:1
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Tidskriftsartikel (refereegranskat)abstract
- To compare the oral microflora in preschool children attending a fluoride varnish program with a reference group receiving a standard oral health program without fluoride varnish applications. A second aim was to relate the microbial composition to the caries prevalence.Five hundred seven 3-year-old children were enrolled from a cohort of 3403 preschool children taking part in a community based oral health project. Two hundred sixty-three of them had attended caries-preventive program with semi-annual applications of a fluoride varnish since the age of 1year (test group) while 237 had received standard preventive care (reference group). Oral samples were collected with a sterile swab and analysed with checkerboard DNA-DNA hybridization using 12 pre-determined bacterial probes. Caries and background data were collected from clinical examinations and questionnaires.Gram-positive streptococci (S. intermedius, S. salivarius, S. oralis) were most frequently detected and displayed the highest counts in both groups. There were no significant differences between the groups concerning prevalence of any of the selected bacterial strains except for S. oralis that occurred less frequently in the reference group. In children with caries, V. parvula were significantly more common (p<0.05) while strains of Lactobacillus, Bifidobacterium and Neisseria were more prevalent among the caries-free children (p<0.05).A 2-year community program with semi-annual fluoride varnish applications did not seem to significantly influence the oral microflora in preschool children.www.controlled-trials.com (ISRCTN35086887) 20131216 'retrospectively registered'.
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| 2. |
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| 3. |
- Dahlén, Gunnar, 1944, et al.
(författare)
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Multiresistenta bakteriestammar - ett problem även för tandvården
- 2016
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Ingår i: Tandläkartidningen. - 0039-6982. ; 108:8, s. 52-56
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Forskningsöversikt (refereegranskat)abstract
- Multiresistenta bakterier är ett globalt växande problem. Mest uppmärksamhet har riktats mot MRSA (meticillin resistenta Staphylococcus aureus), VRE (vancomycin resistenta enterokocker) och ESBL (extended beta-lactamase) stammar bland tarmbakterier (oftast Escherichia coli och Klebsiella arter). Frekvensen orala infektioner med dessa bakterier är relativt låg men en ökning förväntas. De flesta orala infektioner med Staph. aureus, enterokocker eller aeroba Gram-negativa stavar (AGNB) uppträder som opportunistiska infektioner då majoriteten finns på gamla och sjuka patienter eller patienter som av andra skäl är infektionskänsliga. Om multiresistenta bakteriestammar påvisas i orala infektioner skall sådana fall registreras i nationella databaser. Eftersom dessa bakterier också finns hos friska individer (patienter såväl som personal) på huden, i näsan, samt i munhålan måste risken för spridning av dessa bakterier mellan individer på en tandklinik särskilt uppmärksammas. Att iaktta basala hygienrutiner är därför en absolut nödvändighet inom tandvården.
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| 4. |
- Dahlén, Gunnar, 1944, et al.
(författare)
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Subgingival bacterial clusters and serum antibody response as markers of extent and severity of periodontitis in adult Chinese
- 2016
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Ingår i: European Journal of Oral Sciences. - : Wiley. - 0909-8836. ; 124:2, s. 179-187
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Tidskriftsartikel (refereegranskat)abstract
- This study evaluated the associations between clinical, microbiological, and antibody activity manifestations of periodontitis in 123 adult rural Chinese subjects with no dental intervention. All participants were registered for full-mouth clinical attachment level (CAL) and pocket probing depth (PD) measurements, and microbial samples were taken from four sites and analyzed for 18 different bacterial species using the checkerboard'. Serum from each individual was analyzed to determine the antibody activity against the same 18 species. Exploratory factor analysis disclosed two microbial factors - Factor 1, consisting of seven species associated with periodontal health (early colonizers'); and Factor 2, consisting of eight species associated with periodontitis (putative periodontopathogens') - which explained 87% of the variation among the microbial variables. Factor 2 was consistently associated with disease-severity measures, whereas the early colonizer' factor was not. The antibody response showed weak or no correlations with bacterial load or with disease severity. We conclude that the bacteria investigated are resident in the subgingival plaque; that their load and proportions in the pocket may be ecologically driven; and that the antibody response is based on bacterial carrier state rather than on disease. The different antibody-response pattern found between the individuals may suggest that each individual could be classified as a good or a weak immune responder.
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| 5. |
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| 6. |
- Larsen, T, et al.
(författare)
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Orale bakterier og sygdomme udenfor mundhulen
- 2016
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Ingår i: Tandlægebladet. - 0039-9353. ; 120:5, s. 436-441
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Forskningsöversikt (refereegranskat)abstract
- Orale bakterier og sygdomme i mundhulen er blevet kaedet sammen med en raekke forskelige infektöse og inflammatoriske sygdomme udenför mundhulen. Oprindeligt har der vaeret fokus på ekstraorale infektiooner, hvor orale bakterier direkte kan påvises, först og fremmest infektös endocarditis. Siden har interessen bredt sig til sygdomme med mulig faelles inflammatorisk baggrund, og hvor der er påvist epidemiologiske sammanhaenge som fx aterosklerose og diabetes mellitus. Denne artikel giver en oversigt over de mulige sammanhaenge mellem orale bakterier og inflammationsprocesser i mundhulen og sygdomme andre steder i organismen. Mulige mekanismer for en kausal sammanaeng beskrives, og graden af dokumentation for sammenhaeng med orale forhold i relation til de enkelte sygdomme vurderes
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| 7. |
- Larsson Wexell, Cecilia, 1965, et al.
(författare)
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Antimicrobial Effect of a Single Dose of Amoxicillin on the Oral Microbiota.
- 2016
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Ingår i: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899. ; 18:6, s. 609-706
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Tidskriftsartikel (refereegranskat)abstract
- Amoxicillin is commonly used in oral surgery for antimicrobial prophylaxis against surgical-site infection and bacteremia because of its effect on oral streptococci. The aim of this study was to determine whether amoxicillin reaches the break-point concentrations in saliva and has any effect on the salivary microbiota, colonizing bacteria on mucosal membranes and on the gingival crevice after a single dose of amoxicillin.
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