| 1. |
- Bachar-Wikstrom, Etty, et al.
(författare)
-
Mass Spectrometry Analysis of Shark Skin Proteins
- 2023
-
Ingår i: International Journal of Molecular Sciences. - 1661-6596 .- 1422-0067. ; 24:23
-
Tidskriftsartikel (refereegranskat)abstract
- The mucus layer covering the skin of fish has several roles, including protection against pathogens and mechanical damage in which proteins play a key role. While proteins in the skin mucus layer of various common bony fish species have been explored, the proteins of shark skin mucus remain unexplored. In this pilot study, we examine the protein composition of the skin mucus in spiny dogfish sharks and chain catsharks through mass spectrometry (NanoLC-MS/MS). Overall, we identified 206 and 72 proteins in spiny dogfish (Squalus acanthias) and chain catsharks (Scyliorhinus retifer), respectively. Categorization showed that the proteins belonged to diverse biological processes and that most proteins were cellular albeit a significant minority were secreted, indicative of mucosal immune roles. The secreted proteins are reviewed in detail with emphasis on their immune potentials. Moreover, STRING protein–protein association network analysis showed that proteins of closely related shark species were more similar as compared to a more distantly related shark and a bony fish, although there were also significant overlaps. This study contributes to the growing field of molecular shark studies and provides a foundation for further research into the functional roles and potential human biomedical implications of shark skin mucus proteins.
|
|
| 2. |
|
|
| 3. |
- Sinha, Ashirwad, et al.
(författare)
-
Age of Information with On-Off Service
- 2023
-
Ingår i: 2023 IEEE INFORMATION THEORY WORKSHOP, ITW. - : IEEE. - 9798350301496 - 9798350301502 ; , s. 445-450
-
Konferensbidrag (refereegranskat)abstract
- This paper considers a communication system where a source sends time-sensitive information to its destination. We assume that both arrival and service processes of the messages are memoryless and the source has a single server with no buffer. Besides, we consider that the service is interrupted by an independent random process, which we model using an On-Off process. For this setup, we study the age of information for two queueing disciplines: 1) non-preemptive, where the messages arriving while the server is occupied are discarded, and 2) preemptive, where the in-service messages are replaced with newly arriving messages in the Off states. For these disciplines, we derive closed-form expressions for the mean peak age and mean age.
|
|
