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Multisite Assessmen...
Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG)
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- Kovacs, Gabor G. (författare)
- Med Univ Vienna, Inst Neurol, AKH 4J,Wahringer Gurtel 18-20, A-1097 Vienna, Austria.;Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.
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- Xie, Sharon X. (författare)
- Univ Penn, Dept Biostat & Epidemiol, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.
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- Lee, Edward B. (författare)
- Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.
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visa fler...
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- Robinson, John L. (författare)
- Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.
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- Caswell, Carrie (författare)
- Univ Penn, Dept Biostat & Epidemiol, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.
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- Irwin, David J. (författare)
- Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.
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- Toledo, Jon B. (författare)
- Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.
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- Johnson, Victoria E. (författare)
- Univ Penn, Dept Neurosurg, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.
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- Smith, Douglas H. (författare)
- Univ Penn, Dept Neurosurg, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.
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- Alafuzoff, Irina (författare)
- Uppsala universitet,Klinisk och experimentell patologi
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- Attems, Johannes (författare)
- Newcastle Univ, Inst Neurosci, Newcastle Upon Tyne, Tyne & Wear, England.
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- Bencze, Janos (författare)
- Univ Debrecen, Dept Neuropathol, Inst Pathol, Fac Med, Debrecen, Hungary.
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- Bieniek, Kevin F. (författare)
- Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.
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- Bigio, Eileen H. (författare)
- Northwestern Univ, Feinberg Sch Med, Northwestern ADC Neuropathol Core, Chicago, IL 60611 USA.
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- Bodi, Istvan (författare)
- Kings Coll Hosp London, Clin Neuropathol, London, England.;London Neurodegenerat Brain Bank, London, England.
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- Budka, Herbert (författare)
- Med Univ Vienna, Inst Neurol, AKH 4J,Wahringer Gurtel 18-20, A-1097 Vienna, Austria.;Univ Hosp Zurich, Inst Neuropathol, Zurich, Switzerland.
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- Dickson, Dennis W. (författare)
- Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.
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- Dugger, Brittany N. (författare)
- Univ Calif San Francisco, Inst Neurodegenerat Dis, San Francisco, CA 94143 USA.
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- Duyckaerts, Charles (författare)
- UPMC Sorbonne Univ, Dept Neuropathol, Hop La Salpetriere, AP HP, Paris, France.
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- Ferrer, Isidro (författare)
- Univ Barcelona, Inst Neuropathol, Bellvitge Univ Hosp, CIBERNED, Barcelona, Spain.
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- Forrest, Shelley L. (författare)
- Univ Sydney, Sydney Med Sch, Discipline Pathol, Sydney, NSW, Australia.
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- Gelpi, Ellen (författare)
- Inst Invest Biomed Pi &, Neurol Tissue Bank, Biobank Hosp Clin IDIBAPS, Barcelona, Spain.
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- Gentleman, Stephen M. (författare)
- Imperial Coll London, Dept Med, London, England.
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- Giaccone, Giorgio (författare)
- IRCCS Fdn Carlo Besta Neurol Inst, Milan, Italy.
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- Grinberg, Lea T. (författare)
- Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA USA.;Univ Sao Paulo, Sch Med, LIM, Dept Pathol, Sao Paulo, Brazil.
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- Halliday, Glenda M. (författare)
- Univ Sydney, Brain & Mind Ctr, Sydney Med Sch, Sydney, NSW, Australia.;UNSW Med & NeuRA, Sydney, NSW, Australia.
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- Hatanpaa, Kimmo J. (författare)
- Univ Texas Southwestern Med Ctr Dallas, Dept Pathol, Dallas, TX USA.
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- Hof, Patrick R. (författare)
- Icahn Sch Med Mt Sinai, Fishberg Dept Neurosci, Friedman Brain Inst, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Ronald M Loeb Ctr Alzheimers Dis, New York, NY 10029 USA.
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- Hofer, Monika (författare)
- John Radcliffe Hosp, Dept Neuropathol, Oxford, England.
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- Hortobagyi, Tibor (författare)
- Univ Debrecen, Dept Neuropathol, Inst Pathol, Fac Med, Debrecen, Hungary.
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- Ironside, James W. (författare)
- Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland.
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- King, Andrew (författare)
- Kings Coll Hosp London, Clin Neuropathol, London, England.;London Neurodegenerat Brain Bank, London, England.
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- Kofler, Julia (författare)
- Univ Pittsburgh, Dept Pathol, Pittsburgh, PA USA.
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- Kovari, Eniko (författare)
- Univ Hosp, Dept Mental Hlth & Psychiat, Geneva, Switzerland.;Univ Geneva, Sch Med, Geneva, Switzerland.
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- Kril, Jillian J. (författare)
- Univ Sydney, Sydney Med Sch, Discipline Pathol, Sydney, NSW, Australia.
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- Love, Seth (författare)
- Univ Bristol, Inst Clin Neurosci, Southmead Hosp, Learning & Res Level 2, Bristol, Avon, England.
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- Mackenzie, Ian R. (författare)
- Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC, Canada.
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- Mao, Qinwen (författare)
- Northwestern Univ, Feinberg Sch Med, Northwestern ADC Neuropathol Core, Chicago, IL 60611 USA.
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- Matej, Radoslav (författare)
- Thomayer Hosp, Dept Pathol & Mol Med, Prague, Czech Republic.;Charles Univ Prague, Dept Pathol, Med Fac 1, Prague, Czech Republic.
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- McLean, Catriona (författare)
- Alfred Hosp, Dept Anat Pathol, Prahran, Vic, Australia.
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- Munoz, David G. (författare)
- St Michaels Hosp, Div Pathol, Toronto, ON, Canada.
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- Murray, Melissa E. (författare)
- Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.
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- Neltner, Janna (författare)
- Univ Kentucky, Dept Pathol, Lexington, KY USA.;Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA.
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- Nelson, Peter T. (författare)
- Univ Kentucky, Dept Pathol, Lexington, KY USA.;Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA.
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- Ritchie, Diane (författare)
- Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland.
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- Rodriguez, Roberta D. (författare)
- Univ Sao Paulo, Sch Med, Physiopathol Aging Lab, Brazilian Aging Brain Study Grp LIM22, Sao Paulo, Brazil.;Univ Sao Paulo, Behav & Cognit Neurol Unit, Dept Neurol, Sao Paulo, Brazil.
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- Rohan, Zdenek (författare)
- Thomayer Hosp, Dept Pathol & Mol Med, Prague, Czech Republic.;Charles Univ Prague, Dept Pathol, Med Fac 1, Prague, Czech Republic.
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- Rozemuller, Annemieke (författare)
- Netherlands Brainbank, Amsterdam, Netherlands.;Vrije Univ Amsterdam, Dept Pathol, Med Ctr, Amsterdam, Netherlands.
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- Sakai, Kenji (författare)
- Kanazawa Univ, Grad Sch Med Sci, Dept Neurol & Neurobiol Aging, Kanazawa, Ishikawa, Japan.
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- Schultz, Christian (författare)
- Heidelberg Univ, Inst Neuroanat, Ctr Biomed & Med Technol Mannheim, Med Fac Mannheim, Heidelberg, Germany.
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- Seilhean, Danielle (författare)
- UPMC Sorbonne Univ, Dept Neuropathol, Hop La Salpetriere, AP HP, Paris, France.
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- Smith, Vanessa (författare)
- Univ Kentucky, Dept Pathol, Lexington, KY USA.;Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA.
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- Tacik, Pawel (författare)
- Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.;Univ Bonn, Med Ctr, Dept Neurodegenerat Dis & Gerontopsychiat, Bonn, Germany.
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- Takahashi, Hitoshi (författare)
- Niigata Univ, Brain Res Inst, Dept Pathol, Niigata, Japan.
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- Takao, Masaki (författare)
- Saitama Med Univ, Int Med Ctr, Dept Neurol, Saitama, Japan.
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- Thal, Dietmar Rudolf (författare)
- Katholieke Univ Leuven, Dept Neurosci, Leuven, Belgium.;Univ Ziekenhuizen Leuven, Dept Pathol, Leuven, Belgium.
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- Weis, Serge (författare)
- Johannes Kepler Univ Linz, Neuropathol Lab, Dept Pathol & Neuropathol, Kepler Univ Hosp,Med Sch, Linz, Austria.
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- Wharton, Stephen B. (författare)
- Univ Sheffield, Sheffield Inst Translat Neurosci, Sheffield, S Yorkshire, England.
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- White, Charles L., III (författare)
- Univ Texas Southwestern Med Ctr Dallas, Dept Pathol, Dallas, TX USA.
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- Woulfe, John M. (författare)
- Univ Ottawa, Dept Pathol & Lab Med, Ctr Canc Therapeut, Ottawa Hosp,Res Inst, Ottawa, ON, Canada.
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- Yamada, Masahito (författare)
- Kanazawa Univ, Grad Sch Med Sci, Dept Neurol & Neurobiol Aging, Kanazawa, Ishikawa, Japan.
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- Trojanowski, John Q. (författare)
- Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.
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Med Univ Vienna, Inst Neurol, AKH 4J,Wahringer Gurtel 18-20, A-1097 Vienna, Austria;Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA. Univ Penn, Dept Biostat & Epidemiol, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA. (creator_code:org_t)
- 2017-06-07
- 2017
- Engelska.
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Ingår i: Journal of Neuropathology and Experimental Neurology. - : Oxford University Press (OUP). - 0022-3069 .- 1554-6578. ; 76:7, s. 605-619
- Relaterad länk:
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https://academic.oup...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Aging-related tau astrogliopathy (ARTAG) is a recently introduced terminology. To facilitate the consistent identification of ARTAG and to distinguish it from astroglial tau pathologies observed in the primary frontotemporal lobar degeneration tauopathies we evaluated how consistently neuropathologists recognize (1) different astroglial tau immunoreactivities, including those of ARTAG and those associated with primary tauopathies (Study 1); (2) ARTAG types (Study 2A); and (3) ARTAG severity (Study 2B). Microphotographs and scanned sections immunostained for phosphorylated tau (AT8) were made available for download and preview. Percentage of agreement and kappa values with 95% confidence interval (CI) were calculated for each evaluation. The overall agreement for Study 1 was > 60% with a kappa value of 0.55 (95% CI 0.433-0.645). Moderate agreement (> 90%, kappa 0.48, 95% CI 0.457-0.900) was reached in Study 2A for the identification of ARTAG pathology for each ARTAG subtype (kappa 0.37-0.72), whereas fair agreement (kappa 0.40, 95% CI 0.341-0.445) was reached for the evaluation of ARTAG severity. The overall assessment of ARTAG showed moderate agreement (kappa 0.60, 95% CI 0.534-0.653) among raters. Our study supports the application of the current harmonized evaluation strategy for ARTAG with a slight modification of the evaluation of its severity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Aging
- ARTAG
- Digital pathology
- Interrater agreement
- Neuropathology
- Tau
- Tau-astrogliopathy
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- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Kovacs, Gabor G.
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Xie, Sharon X.
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Lee, Edward B.
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Robinson, John L ...
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Caswell, Carrie
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Irwin, David J.
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visa fler...
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Toledo, Jon B.
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Johnson, Victori ...
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Smith, Douglas H ...
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Alafuzoff, Irina
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Attems, Johannes
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Bencze, Janos
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Bieniek, Kevin F ...
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Bigio, Eileen H.
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Bodi, Istvan
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Budka, Herbert
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Dickson, Dennis ...
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Dugger, Brittany ...
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Duyckaerts, Char ...
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Ferrer, Isidro
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Forrest, Shelley ...
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Gelpi, Ellen
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Gentleman, Steph ...
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Giaccone, Giorgi ...
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Grinberg, Lea T.
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Halliday, Glenda ...
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Hatanpaa, Kimmo ...
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Hof, Patrick R.
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Hofer, Monika
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Hortobagyi, Tibo ...
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Ironside, James ...
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King, Andrew
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Kofler, Julia
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Kovari, Eniko
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Kril, Jillian J.
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Love, Seth
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Mackenzie, Ian R ...
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Mao, Qinwen
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Matej, Radoslav
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McLean, Catriona
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Munoz, David G.
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Murray, Melissa ...
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Neltner, Janna
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Nelson, Peter T.
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Ritchie, Diane
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Rodriguez, Rober ...
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Rohan, Zdenek
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Rozemuller, Anne ...
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Sakai, Kenji
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Schultz, Christi ...
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Seilhean, Daniel ...
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Smith, Vanessa
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Tacik, Pawel
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Takahashi, Hitos ...
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Takao, Masaki
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Thal, Dietmar Ru ...
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Weis, Serge
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Wharton, Stephen ...
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White, Charles L ...
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Woulfe, John M.
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Yamada, Masahito
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Trojanowski, Joh ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
- Artiklar i publikationen
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Journal of Neuro ...
- Av lärosätet
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Uppsala universitet