Sökning: (WFRF:(Hermansen Kjeld)) srt2:(2020-2023)
> (2023) >
Fatty acid composit...
Fatty acid composition of cholesterol esters reflects dietary fat intake after dietary interventions in a multinational population
-
Salamone, Dominic (författare)
-
- Annuzzi, Giovanni (författare)
- Univ Naples Federico II, Dept Clin Med & Surg, Med Sch, Via Pansini 5, I-80131 Naples, Italy. Univ Naples Federico II, Task Force Microbiome Studies, Naples, Italy. Uppsala Univ, Dept Publ Hlth & Caring Sci, Clin Nutr & Metab, Uppsala, Sweden. Aarhus Univ, Dept Clin Med, Aarhus, Denmark. Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland. Univ Wollongong, Sch Med Indigenous & Hlth Sci, Wollongong, Australia. Univ Wollongong, Illawarra Hlth & Med Res Inst, Wollongong, Australia. Univ Wollongong, Mol Horizons, Wollongong, Australia.
-
- Vessby, Bengt (författare)
- Uppsala universitet,Klinisk nutrition och metabolism
-
visa fler...
-
Rivellese, Angela A. (författare)
-
Bozzetto, Lutgarda (författare)
-
Costabile, Giuseppina (författare)
-
Hermansen, Kjeld (författare)
-
Uusitupa, Matti (författare)
-
Meyer, Barbara J. (författare)
-
Riccardi, Gabriele (författare)
-
visa färre...
-
Univ Naples Federico II, Dept Clin Med & Surg, Med Sch, Via Pansini 5, I-80131 Naples, Italy Univ Naples Federico II, Task Force Microbiome Studies, Naples, Italy. Uppsala Univ, Dept Publ Hlth & Caring Sci, Clin Nutr & Metab, Uppsala, Sweden. Aarhus Univ, Dept Clin Med, Aarhus, Denmark. Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland. Univ Wollongong, Sch Med Indigenous & Hlth Sci, Wollongong, Australia. Univ Wollongong, Illawarra Hlth & Med Res Inst, Wollongong, Australia. Univ Wollongong, Mol Horizons, Wollongong, Australia. Klinisk nutrition och metabolism (creator_code:org_t)
- Elsevier, 2023
- 2023
- Engelska.
-
Ingår i: Journal of Clinical Lipidology. - : Elsevier. - 1933-2874 .- 1876-4789. ; 17:4, s. 466-474
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- BackgroundThe effects of different dietary fatty acids (FA) on cardiovascular risk still needs clarification. Plasma lipids composition may be a biomarker of FA dietary intake.PurposeTo evaluate in a composite population the relationships between changes in dietary fat intake and changes in FA levels in serum cholesterol esters.MethodsIn a multinational, parallel-design, dietary intervention (KANWU study), dietary intakes (3-day food record) and FA composition of serum cholesterol esters (gas-liquid chromatography) were evaluated at baseline and after 3 months in 162 healthy individuals, randomly assigned to a diet containing a high proportion of saturated (SFA) or monounsaturated (MUFA) fat, with a second random assignment to fish oil or placebo supplements.ResultsMain differences in serum lipid composition after the two diets included saturated (especially myristic, C14:0, and pentadecanoic, C15:0) and monounsaturated (oleic acid, C18:1 n-9) FA. C14:0 and C15:0 were related to SFA intake, while C18:1 n-9 was associated with MUFA intake. Fish oil supplementation induced a marked increase in eicosapentaenoic (C20:5 n-3) and docosahexaenoic (C22:6 n-3) acids. After the 3-month intervention, Δ-9 desaturase activity, calculated as palmitoleic acid/palmitic acid (C16:1/C16:0) ratio, was more reduced after the MUFA (0.31±0.10 vs 0.25±0.09, p<0.0001) than SFA diet (0.31±0.09 vs 0.29±0.08, p=0.006), with a statistically significant difference between the two groups (p<0.0001).ConclusionsThis study shows that serum cholesterol ester FA composition can be used during randomized controlled trials as an objective indicator of adherence to experimental diets based on saturated and monounsaturated fat modifications, as well as fish oil supplementation.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- LANTBRUKSVETENSKAPER -- Lantbruksvetenskap, skogsbruk och fiske -- Livsmedelsvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Agriculture, Forestry and Fisheries -- Food Science (hsv//eng)
Nyckelord
- Dietary saturated fatty acids
- Monounsaturated fatty acids
- Serum lipid fatty acid composition
- Dietary intervention
- Fish oil
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Salamone, Domini ...
-
Annuzzi, Giovann ...
-
Vessby, Bengt
-
Rivellese, Angel ...
-
Bozzetto, Lutgar ...
-
Costabile, Giuse ...
-
visa fler...
-
Hermansen, Kjeld
-
Uusitupa, Matti
-
Meyer, Barbara J ...
-
Riccardi, Gabrie ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Näringslära
-
- LANTBRUKSVETENSKAPER
-
LANTBRUKSVETENSK ...
-
och Lantbruksvetensk ...
-
och Livsmedelsvetens ...
- Artiklar i publikationen
-
Journal of Clini ...
- Av lärosätet
-
Uppsala universitet