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- Juday, G.P, et al.
(author)
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Chapter 14: Forests, Land Management and Agriculture
- 2005
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In: The Arctic Climate Impact Assessment - The Scientific Report. - Cambridge : Cambridge University Press. - 0521865093 ; , s. 781-862
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Book chapter (other academic/artistic)
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3. |
- Tirri, M E, et al.
(author)
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Two-photon excitation in fluorescence polarization receptor-ligand binding assay
- 2005
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In: Journal of Biomolecular Screening. - : Elsevier BV. - 1087-0571. ; 10:4, s. 314-319
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Journal article (peer-reviewed)abstract
- Fluorescence polarization is one of the most commonly used homogeneous assay principles in drug discovery for screening of potential lead compounds. In this article, the fluorescence polarization technique is combined with 2-photon excitation of fluorescence. Theoretically, the use of 2-photon excitation of fluorescence increases the volumetric sensitivity and polarization contrast of fluorescence polarization assays. The work in this report demonstrates these predictions for an estrogen receptor ligand binding assay.
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