| 1. |
- Hoffman, Johan, 1974-, et al.
(författare)
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Turbulent flow and Fluid–structure interaction
- 2012
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Ingår i: Lecture Notes in Computational Science and Engineering. - : Springer Science and Business Media Deutschland GmbH. ; , s. 543-552
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Bokkapitel (refereegranskat)abstract
- The FEniCS Project aims towards the goals of generality, efficiency, and simplicity, concerning mathematical methodology, implementation and application, and the Unicorn project is an implementation aimed at FSI and high Re turbulent flow guided by these principles. Unicorn is based on the DOLFIN/FFC/FIAT suite and the linear algebra package PETSc. We here present some key elements of Unicorn, and a set of computational results from applications. The details of the Unicorn implementation are described in Chapter 18.
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| 2. |
- Hoffman, Johan, 1974-, et al.
(författare)
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Unicorn : A unified continuum mechanics solver
- 2012
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Ingår i: Lecture Notes in Computational Science and Engineering. - : Springer Science and Business Media Deutschland GmbH. ; , s. 339-361
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Bokkapitel (refereegranskat)abstract
- This chapter provides a description of the technology of Unicorn focusing on simple, efficient and general algorithms and software for the Unified Continuum (UC) concept and the adaptive General Galerkin (G2) discretization as a unified approach to continuum mechanics. We describe how Unicorn fits into the FEniCS framework, how it interfaces to other FEniCS components, what interfaces and functionality Unicorn provides itself and how the implementation is designed. We also present some examples in fluid–structure interaction and adaptivity computed with Unicorn.
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| 3. |
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| 4. |
- Jansson, Johan, 1978-, et al.
(författare)
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Simulation of 3D unsteady incompressible flow past a NACA 0012 wing section
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- We present computational simulations of three-dimensional unsteady high Reynolds number incompressible flow past a NACA 0012 wing profile, for a range of angles of attack, from low lift through stall. A stabilized finite element method is used, referred to as General Galerkin (G2), with adaptive mesh refinement with respect to the error in target output, such as aerodynamic forces. Computational predictions of aerodynamic forces are validated against experimental data.
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| 5. |
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| 6. |
- Jansson, Niclas, et al.
(författare)
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Framework For Massively Parallel Adaptive Finite Element Computational Fluid Dynamics On Tetrahedral Meshes
- 2012
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Ingår i: SIAM Journal on Scientific Computing. - : Society for Industrial & Applied Mathematics (SIAM). - 1064-8275 .- 1095-7197. ; 34:1, s. C24-C42
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Tidskriftsartikel (refereegranskat)abstract
- In this paper we describe a general adaptive finite element framework for unstructured tetrahedral meshes without hanging nodes suitable for large scale parallel computations. Our framework is designed to scale linearly to several thousands of processors, using fully distributed and efficient algorithms. The key components of our implementation, local mesh refinement and load balancing algorithms, are described in detail. Finally, we present a theoretical and experimental performance study of our framework, used in a large scale computational fluid dynamics computation, and we compare scaling and complexity of different algorithms on different massively parallel architectures.
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| 7. |
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| 8. |
- Sarwar, Nadeem, et al.
(författare)
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Interleukin-6 receptor pathways in coronary heart disease : a collaborative meta-analysis of 82 studies
- 2012
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Ingår i: The Lancet. - New York, NY, USA : Elsevier. - 0140-6736 .- 1474-547X. ; 379:9822, s. 1205-1213
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Tidskriftsartikel (refereegranskat)abstract
- Background: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades. To assess whether this pathway is causally relevant to coronary heart disease, we studied a functional genetic variant known to affect IL6R signalling. Methods: In a collaborative meta-analysis, we studied Asp358Ala (rs2228145) in IL6R in relation to a panel of conventional risk factors and inflammation biomarkers in 125 222 participants. We also compared the frequency of Asp358Ala in 51 441 patients with coronary heart disease and in 136 226 controls. To gain insight into possible mechanisms, we assessed Asp358Ala in relation to localised gene expression and to postlipopolysaccharide stimulation of interleukin 6. Findings: The minor allele frequency of Asp358Ala was 39%. Asp358Ala was not associated with lipid concentrations, blood pressure, adiposity, dysglycaemia, or smoking (p value for association per minor allele >= 0.04 for each). By contrast, for every copy of 358Ala inherited, mean concentration of IL6R increased by 34.3% (95% CI 30.4-38.2) and of interleukin 6 by 14.6% (10.7-18.4), and mean concentration of C-reactive protein was reduced by 7.5% (5.9-9.1) and of fibrinogen by 1.0% (0.7-1.3). For every copy of 358Ala inherited, risk of coronary heart disease was reduced by 3.4% (1.8-5.0). Asp358Ala was not related to IL6R mRNA levels or interleukin-6 production in monocytes. Interpretation: Large-scale human genetic and biomarker data are consistent with a causal association between IL6R-related pathways and coronary heart disease.
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| 9. |
- Albrektsson, Joakim, et al.
(författare)
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Assessment of fire exposed concrete structures
- 2012
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Ingår i: fib Symposium 2012: Concrete Structures for Sustainable Community. - 9789198009811 ; , s. 619-622, s. 619-622
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Konferensbidrag (refereegranskat)abstract
- Annually, several concrete structures, such as buildings, bridges, parking garages and tunnels are exposed to fires. An assessment is then necessary to decide whether the structure can be repaired or needs to be replaced. In a recent research project, recommendations for assessments of fire exposed concrete structures have been developed. The recommendations are based on a literature survey, results from an experimental study, where ultrasonic measurements, microscopy, Digital Image Correlation (DIC) measurement on loaded core samples were used and practical experience of real post-fire structural assessments. A refined assessment of the fire damage is obtained by combining these test methods.
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| 10. |
- Bäck, Maria, 1978, et al.
(författare)
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Validation of a questionnaire to detect kinesiophobia (fear of movement) in patients with coronary artery disease
- 2012
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Ingår i: Journal of Rehabilitation Medicine. - : Medical Journals Sweden AB. - 1651-2081 .- 1650-1977. ; 44:4, s. 363-369
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To investigate the validity and reliability of the Tampa Scale for Kinesiophobia Heart (TSK-SV Heart), which is a brief questionnaire to detect kinesiophobia (fear of movement), in patients with coronary artery disease (CAD). Design: Methodological research (cross-sectional study). Subjects: A total of 332 patients, mean age, 65±9.1 years diagnosed with CAD at a university hospital were included in the study. Methods: The psychometric properties of the TSK-SV Heart were tested. The tests of validity comprised face validity, content validity, and construct validity. The reliability tests included composite reliability, internal consistency and stability over time. Results: In terms of reliability, the TSK-SV Heart was found to be stable over time (Intra Class Correlation coefficient = 0.83), and internally consistent (Cronbach’s alpha = 0.78). A confirmatory factor analysis provided acceptable fit for a hypothesized four-factor model with inclusion of a method factor. Conclusions: These results provide support showing the TSK-SV Heart to be reliable and the questionnaire seems to be valid for use in patients with CAD. However, some items need further investigation due to low influence on some sub-dimensions of the test. The sub-dimensions of kinesiophobia require future studies concerning their implications for the target group.
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