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Sökning: (WFRF:(Judson D.)) srt2:(2010-2014) > (2014)

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1.
  • Pellegri, L., et al. (författare)
  • Pygmy dipole resonance in Sn-124 populated by inelastic scattering of O-17
  • 2014
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 738, s. 519-523
  • Tidskriftsartikel (refereegranskat)abstract
    • The gamma decay from the high-lying states of Sn-124 was measured using the inelastic scattering of O-17 at 340 MeV. The emitted gamma rays were detected with high resolution with the AGATA demonstrator array and the scattered ions were detected in two segmented Delta E-E silicon telescopes. The angular distribution was measured both for the gamma rays and the scattered O-17 ions. An accumulation of E1 strength below the particle threshold was found and compared with previous data obtained with (gamma,gamma') and (alpha,alpha'gamma) reactions. The present results of elastic scattering, and excitation of E2 and E1 states were analysed using the DWBA approach. From this comprehensive description the isoscalar component of the 1-excited states was extracted. The obtained values are based on the comparison of the data with DWBA calculations including a form factor deduced using a microscopic transition density.
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2.
  • Peura, P., et al. (författare)
  • Quasiparticle alignments and alpha-decay fine structure of Pt-175
  • 2014
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 89:2, s. 024316-
  • Tidskriftsartikel (refereegranskat)abstract
    • Excited states and decay properties of Pt-175 have been investigated using the Mo-92(Sr-86, 2pn) fusion-evaporation reaction. The JUROGAM I gamma-ray spectrometer and the GREAT spectrometer were used in conjunction with the gas-filled recoil separator RITU for the measurement of the radiation at the target and focal plane positions, respectively. Two new band structures, assigned to be based on the I-pi = (7/2(-)) ground state in Pt-175, have been established and the known yrast band has been extended up to I-pi = (49/2(+)). Rotational properties of the excited states in Pt-175 have been investigated within the cranked shell-model formalism. The low-frequency changes in the alignments of the positive-and negative-parity bands are interpreted as a sign of proton-pair excitations in the rotating core. Furthermore, the alpha-decay measurements reveal a candidate for a fourth alpha-decay branch in Pt-175, feeding a non-yrast state in Os-171.
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4.
  • Flavin, Richard, et al. (författare)
  • SPINK1 protein expression and prostate cancer progression
  • 2014
  • Ingår i: Clinical Cancer Research. - Philadelphia, USA : American Association for Cancer Research. - 1078-0432 .- 1557-3265. ; 20:18, s. 4904-11
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: SPINK1 overexpression has been described in prostate cancer and is linked with poor prognosis in many cancers. The objective of this study was to characterize the association between SPINK1 overexpression and prostate cancer-specific survival.Experimental design: The study included 879 participants in the U.S. Physicians' Health Study and Health Professionals Follow-Up Study, diagnosed with prostate cancer (1983-2004) and treated by radical prostatectomy. Protein tumor expression of SPINK1 was evaluated by immunohistochemistry on tumor tissue microarrays.Results: Seventy-four of 879 (8%) prostate cancer tumors were SPINK1 positive. Immunohistochemical data were available for PTEN, p-Akt, pS6, stathmin, androgen receptor (AR), and ERG (as a measure of the TMPRSS2:ERG translocation). Compared with SPINK1-negative tumors, SPINK1-positive tumors showed higher PTEN and stathmin expression, and lower expression of AR (P < 0.01). SPINK1 overexpression was seen in 47 of 427 (11%) ERG-negative samples and in 19 of 427 (4%) ERG-positive cases (P = 0.0003). We found no significant associations between SPINK1 status and Gleason grade or tumor stage. There was no association between SPINK1 expression and biochemical recurrence (P = 0.56). Moreover, there was no association between SPINK1 expression and prostate cancer mortality (there were 75 lethal cases of prostate cancer during a mean of 13.5 years follow-up; HR = 0.71; 95% confidence interval, 0.29-1.76).Conclusions: Our results suggest that SPINK1 protein expression may not be a predictor of recurrence or lethal prostate cancer amongst men treated by radical prostatectomy. SPINK1 and ERG protein expression do not seem to be entirely mutually exclusive, as some previous studies have suggested.
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  • Resultat 1-4 av 4

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