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Träfflista för sökning "(WFRF:(Kopec J. A.)) srt2:(2010-2014)"

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1.	Bellenguez, Celine, et al. (author) Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke 2012 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:3, s. 141-328 Journal article (peer-reviewed)abstract Genetic factors have been implicated in stroke risk, but few replicated associations have been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke and its subtypes in 3,548 affected individuals and 5,972 controls, all of European ancestry. Replication of potential signals was performed in 5,859 affected individuals and 6,281 controls. We replicated previous associations for cardioembolic stroke near PITX2 and ZFHX3 and for large vessel stroke at a 9p21 locus. We identified a new association for large vessel stroke within HDAC9 (encoding histone deacetylase 9) on chromosome 7p21.1 (including further replication in an additional 735 affected individuals and 28,583 controls) (rs11984041; combined P = 1.87 x 10(-11); odds ratio (OR) = 1.42, 95% confidence interval (CI) = 1.28-1.57). All four loci exhibited evidence for heterogeneity of effect across the stroke subtypes, with some and possibly all affecting risk for only one subtype. This suggests distinct genetic architectures for different stroke subtypes.
2.	Clarke, M, et al. (author) Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling 2013 In: Genome biology. - : Springer Science and Business Media LLC. - 1474-760X .- 1465-6906. ; 14:2, s. R11- Journal article (peer-reviewed)
3.	Miotto, P, et al. (author) Mycobacterium tuberculosis pyrazinamide resistance determinants: a multicenter study 2014 In: mBio. - 2150-7511. ; 5:5, s. e01819-14 Journal article (peer-reviewed)
4.	Moynie, L, et al. (author) The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery 2013 In: Acta crystallographica. Section F, Structural biology and crystallization communications. - 1744-3091. ; 69:Pt 1, s. 25-34 Journal article (peer-reviewed)

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Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Liu, B. (1); Rothwell, Peter M. (1); Kittner, Steven J. (1); Meschia, James F (1); Roy, S (1); Clarke, M (1); show more...; Cirillo, DM (1); Sandalova, T (1); Schneider, G (1); Boonen, Steven (1); Deloukas, Panos (1); Hoffner, S (1); Schnell, R (1); Norrving, Bo (1); Dichgans, Martin (1); Rosand, Jonathan (1); Thorleifsson, Gudmar (1); Thorsteinsdottir, Un ... (1); Stefansson, Kari (1); Delavaran, Hossein (1); Lindgren, Arne (1); Sharma, Pankaj (1); Worrall, Bradford B. (1); Peltonen, Leena (1); Chen, N. (1); Farrall, Martin (1); Palmer, Colin N. A. (1); Lagkouvardos, I (1); Ambrosi, A (1); Nalls, Michael A. (1); Valant, Valerie (1); Slowik, Agnieszka (1); Woo, Daniel (1); Pera, Joanna (1); Niemann, S (1); Werngren, J (1); Burglin, TR (1); Casas, Juan P. (1); Mitchell, Braxton D. (1); Meisinger, Christa (1); Trembath, Richard C. (1); Cortellini, Lynelle (1); Thijs, Vincent (1); Kissela, Brett (1); Lemmens, Robin (1); Levi, Chris (1); Markus, Hugh S. (1); Rodionova, Y (1); Casali, N (1); Drobniewski, F (1); show less...

University: Karolinska Institutet (3); Lund University (1)

Language: English (4)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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