| 1. |
- Li, Weiwei, et al.
(författare)
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Benzothiadiazole-Based Linear and Star Molecules : Design, Synthesis, and Their Application in Bulk Heterojunction Organic Solar Cells
- 2009
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Ingår i: CHEMISTRY OF MATERIALS. - : American Chemical Society (ACS). - 0897-4756 .- 1520-5002. ; 21:21, s. 5327-5334
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Tidskriftsartikel (refereegranskat)abstract
- Star molecules have many advantages, such as monodispersity, excellent solubility, and vast structures with different functional groups. A set of four-arm star molecules with benzothiadiazole as the core, oligothiophene its the arm, and triphenylamine its the end group and their linear counterparts were designed and synthesized Organic solar cells (OSCs) fabricated with these star molecules and [6,6]-phenyl C-71 butyric acid methyl ester (PC71BM) by spin-coating from solution demonstrate similar short circuit current density (J(sc)) and fill factor (FF) but larger open circuit voltage (V-oc) in comparison With solar cells fabricated with corresponding linear molecules and PC71BM A power conversion efficiency (PCE) of 18%, with J(sc) = 4.9 mA/cm(2), V-oc = 0 92 V, and FF = 0 41 was achieved with one of these star molecules
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| 2. |
- Hu, Minyu, et al.
(författare)
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Comparison of lycopene and fluvastatin effects on atherosclerosis induced by a high-fat diet in rabbits
- 2008
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Ingår i: Nutrition Journal. - : Elsevier BV. - 1475-2891 .- 1475-2891. ; 24:10, s. 1030-1038
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Tidskriftsartikel (refereegranskat)abstract
- Objective We evaluated the antiatherogenic effect of lycopene in rabbits fed a high-fat diet. Methods Forty adult male rabbits were divided into five groups that were fed a standard diet, a high-fat diet, a high-fat diet plus 4 mg/kg of lycopene, a high-fat diet plus 12 mg/kg of lycopene, and a high-fat diet plus 10 mg/kg of fluvastatin, respectively. Lycopene and fluvastatin were administered intragastrically. The level of serum total cholesterol, total triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, total antioxidant capacity, and malondialdehyde were measured before and after 4 and 8 wk of experimental treatment. In addition, plasma levels of lycopene, oxidized low-density lipoprotein, serum nitric oxide, and interleukin-1 were measured after the experiment. The area of atherosclerotic plaque and pathologic changes of the aorta were evaluated. Results Compared with the control, levels of total cholesterol, total triacylglycerol, low-density lipoprotein cholesterol, malonaldehyde, oxidized low-density lipoprotein, and interleukin-1 were increased and total antioxidant capacity and nitric oxide were decreased in the animals with a high-fat diet (P < 0.05). Intragastric administration of lycopene counteracted the change in these parameters (P < 0.05). In this case, the data showed that lycopene in the used dose was better than the fluvastatin intervention. Morphologic analysis revealed that lycopene and fluvastatin markedly reduced the formation of atherosclerotic plaques in the aorta compared with the situation in rabbits on a high-fat diet alone. Conclusion Lycopene, like fluvastatin, significantly attenuated atherogenesis in rabbits fed a high-fat diet.
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| 3. |
- Klionsky, Daniel J., et al.
(författare)
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
- 2008
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Ingår i: Autophagy. - : Landes Bioscience. - 1554-8627 .- 1554-8635. ; 4:2, s. 151-175
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Forskningsöversikt (refereegranskat)abstract
- Research in autophagy continues to accelerate,1 and as a result many new scientists are entering the field. Accordingly, it is important to establish a standard set of criteria for monitoring macroautophagy in different organisms. Recent reviews have described the range of assays that have been used for this purpose.2,3 There are many useful and convenient methods that can be used to monitor macroautophagy in yeast, but relatively few in other model systems, and there is much confusion regarding acceptable methods to measure macroautophagy in higher eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers of autophagosomes versus those that measure flux through the autophagy pathway; thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from fully functional autophagy that includes delivery to, and degradation within, lysosomes (in most higher eukaryotes) or the vacuole (in plants and fungi). Here, we present a set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes. This set of guidelines is not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to verify an autophagic response.
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| 4. |
- Li, Fenghong, et al.
(författare)
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Tuning Work Function of Noble Metals As Promising Cathodes in Organic Electronic Devices
- 2009
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Ingår i: CHEMISTRY OF MATERIALS. - : American Chemical Society (ACS). - 0897-4756 .- 1520-5002. ; 21:13, s. 2798-2802
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Tidskriftsartikel (refereegranskat)abstract
- Work function (WF) modification of metal electrodes by adsorbing electron-rich or electron-deficient molecules oil metal surfaces has become a field of significant interest. The barrier for charge carrier injection in organic semiconductor devices can be reduced by molecular adsorption, leading to all interfacial dipole. Here, we demonstrate that the WF of noble metals such as ALL call be decreased significantly by adsorbing air stable n-type dopant acridine orange base (AOB) thin film. When a (sub)monolayer AOB is deposited on sputter-cleaned Au, the WF of the substrate changes from 5.2 to 3.5 eV. At complete coverage of the Au Surface, the WF is further reduced to 3.3 eV. When a (sub) monolayer of AOB is inserted between Au and C-60 thin film, the barrier of electron injection is decreased by 0.4 +/- 0.1 eV as compared to an Au-C-60 interface without AOB. Polymer solar cells with AOB/Au as a cathode have a similar open circuit voltage and comparable power conversion efficiency with devices using LiF/Al as a cathode, demonstrating that the AOB-modified gold electrode is an efficient low-work-function contact. Given the low positive pinning energy of 3.3 eV for AOB, we expect that other conventional high-work-function materials (Ag, ITO. La0.7Sr0.3MnO3 and even PEDOT:PSS) can be modified by AOB as effectively as Au.
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| 5. |
- Mendoza-Galvan, Arturo, et al.
(författare)
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Spectroscopic ellipsometry analysis of silicon nanotips obtained by electron cyclotron resonance plasma etching
- 2009
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Ingår i: APPLIED OPTICS. - 0003-6935. ; 48:26, s. 4996-5004
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Tidskriftsartikel (refereegranskat)abstract
- Silicon nanotips fabricated by electron cyclotron resonance plasma etching of silicon wafers are studied by spectroscopic ellipsometry. The structure of the nanotips is composed of columns 100-140 nm wide and spaced by about 200 nm. Ellipsometry data covering a wide spectral range from the midinfrared to the visible are described by modeling the nanotip layer as a graded uniaxial film using the Bruggeman effective medium approximation. The ellipsometry data in the infrared range reveal two absorption bands at 754 and 955 cm(-1), which cannot be resolved with transmittance measurements. These bands indicate that the etching process is accompanied with formation of carbonaceous SiC and CHn species that largely modify the composition of the original crystalline silicon material affecting the optical response of the nanotips. (C) 2009 Optical Society of America
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| 6. |
- Wang, Mo-Jin, et al.
(författare)
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The Ile646Val (2073A > G) Polymorphism in the Kinase-Binding Domain of A-Kinase Anchoring Protein 10 and the Risk of Colorectal Cancer
- 2009
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Ingår i: ONCOLOGY. - : S. Karger AG. - 0030-2414 .- 1423-0232. ; 76:3, s. 199-204
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The purpose of this study is to investigate whether the Ile646Val (2073A>G) polymorphism in the kinase-binding domain of A-kinase anchoring protein 10 (AKAP10) is related to the risk of colorectal cancer (CRC), clinicopathological variables and the environmental factors for the development of CRC. Methods: Applying TaqMan allelic discrimination, we investigated AKAP10 Ile646Val (2073A>G) polymorphism in 288 Chinese CRC patients and 281 healthy controls. Results: Logistic regression analysis revealed a significant association of AKAP10 Ile646Val (2073A>G) polymorphism with increased CRC risk (adjusted OR = 1.44, 95% CI 1.01-2.07, p = 0.02). Stratification analysis showed that the increased risk associated with the variant genotypes (GG+AG) was more evident in male subjects (adjusted OR = 1.48, 95% CI 0.94-2.34, p = 0.03). Compared with the AA genotype, the adjusted OR for the variant genotypes was 1.81 (95% CI 1.08 - 3.05, p = 0.01) among young subjects (age ! 57 years). Among individuals who did not smoke or who smoked lightly, there was a significantly increased risk with the variant genotypes (adjusted OR = 1.66, 95% CI 1.08 - 2.56, p = 0.02). We did not observe a relationship between the AKAP10 polymorphism and other clinicopathological and environmental factors. Conclusions: Our data suggested that the AKAP10 2073A>G variation is associated with an increased risk of CRC in the Chinese population.
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| 7. |
- Wu, Di, 1979-, et al.
(författare)
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Real-Time Space-Time Adaptive Processing on the STI CELL Multiprocessor
- 2007
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Ingår i: 4th European Radar Conference,2007. - : IEEE. - 9782874870040 ; , s. 71-74
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Konferensbidrag (refereegranskat)abstract
- Space-time adaptive processing (STAP) has been widely used in modern radar systems such as ground moving target indication (GMTI) systems in order to suppress jamming and interference. However, its baseband signal processing part usually requires huge amount of computing power. This paper presents the real-time implementation of an STAP baseband signal processing flow on the state-of-the-art STI CELL multiprocessor which enables the concept of software-defined radar (SDR). SIMD vectorization is applied to speed-up the kernel subroutines of STAP such as the QR decomposition, forward/backward substitution and fast Fourier transform (FFT). Benchmarking results of both the kernel subroutines and the overall flow are presented. Furthmore, based on the result of earlier benchmarking, optimized task partitioning and scheduling methods are proposed by us to improve the overall performance so that the overhead is reduced to the minimum.
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