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- Borga, Magnus, et al.
(författare)
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Brown adipose tissue in humans: detection and functional analysis using PET (positron emission tomography), MRI (magnetic resonance imaging), and DECT (dual energy computed tomography).
- 2014
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Ingår i: Methods in enzymology. - : Elsevier. - 1557-7988. ; 537, s. 141-59, s. 141-159
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Tidskriftsartikel (refereegranskat)abstract
- If the beneficial effects of brown adipose tissue (BAT) on whole body metabolism, as observed in nonhuman experimental models, are to be translated to humans, tools that accurately measure how BAT influences human metabolism will be required. This chapter discusses such techniques, how they can be used, what they can measure and also some of their limitations. The focus is on detection and functional analysis of human BAT and how this can be facilitated by applying advanced imaging technology such as positron emission tomography, magnetic resonance imaging, and dual energy computed tomography.
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- Karlsson, Anette, et al.
(författare)
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Automatic and Quantitative Assessment of Total and Regional Muscle Tissue Volume using Multi-Atlas Segmentation
- 2014
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Accurate and precise assessment of human muscle tissue is important for further understanding of different muscle diseases and syndromes. We present a rapid whole body MR method for automatic quantification of total and regional muscle volume. The method is based on multi-atlas segmentation of intensity corrected water-fat separated images. The method was validated with a leave-one-out approach, using manually segmented atlases from 10 subjects as ground truth. The result gave a coefficient of variation on total muscle volume equal to 1.25±1.35 % (mean ± standard deviation). The method enables cost-efficient large-scale studies, investigating conditions such as sarcopenia and muscular dystrophies.
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- Lidell, Martin, 1970, et al.
(författare)
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Evidence for two types of brown adipose tissue in humans
- 2013
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Ingår i: Nature Medicine. - : Springer Science and Business Media LLC. - 1078-8956 .- 1546-170X. ; 19:5, s. 631-634
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Tidskriftsartikel (refereegranskat)abstract
- The previously observed supraclavicular depot of brown adipose tissue (BAT) in adult humans was
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