| 1. |
- Johanson, Per, 1963, et al.
(författare)
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Time-trends in thrombolytics: women are catching up.
- 1999
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Ingår i: Scandinavian cardiovascular journal : SCJ. - 1401-7431. ; 33:1, s. 39-43
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Tidskriftsartikel (refereegranskat)abstract
- Reports on gender differences in the management of acute coronary syndromes indicate that women do not receive as much active treatment as men. Other conflicting findings have also been published. To investigate whether previously reported gender differences in the treatment of acute myocardial infarction (AMI) still persist, we included all patients admitted to our coronary care unit (CCU) in 1984-1995, and discharged with a diagnosis of AMI, in a retrospective study. A total of 1991 female admissions was compared with 4067 male admissions. The time-span was divided into two-year periods comprising approximately 1000 patients each. During one period, 1988 to 1989, women received significantly less thrombolytic therapy which, however, could reflect that women admitted with AMI were older than men. Analysis of time-trends showed a significant increase in the use of thrombolytic treatment in women and elderly men. In clinical praxis there has been a gender-gap in acute treatment of AMI, but age-dependent or not, this is now no longer apparent.
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| 2. |
- Welin, Catharina, 1945, et al.
(författare)
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Behavioural characteristics in patients with myocardial infarction: a case-control study
- 1995
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Ingår i: Journal of Cardiovascular Risk. - 1350-6277. ; 2:3, s. 247-254
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Over the past 10-20 years, evidence has accumulated suggesting that it is not just biological risk factors that are important for the development of coronary heart disease. The present study is one of a series of case-control studies in which a wide range of psychosocial factors have been analysed in the same population to obtain information on their relationship with myocardial infarction, as well as of the interaction between psychosocial and biomedical variables. METHODS: The relationship between behavioural factors and non-fatal myocardial infarction was studied by comparing consecutively admitted male (n = 288) and female (n = 55) patients with a population sample of 283 men and 129 women. All participants were under 65 years of age. The behavioural variables (type-A behaviour, health locus of control, sleep problems and alcohol consumption) were investigated by means of a self-administered questionnaire. RESULTS: No significant differences emerged between patients with myocardial infarction and controls in terms of their type-A behaviour pattern. After controlling for traditional risk factors (smoking, hypertension, serum cholesterol level and diabetes), men with myocardial infarction reported a significantly stronger external health locus of control (i.e. a weak belief in their capacity to control their health) compared with their controls, as well as more problems with sleep and a lower alcohol consumption; women with myocardial infarction reported significantly more problems with sleep than their controls. CONCLUSION: The importance of health locus of control, sleep problems and alcohol consumption is amplified by the fact that they are related to myocardial infarction independently of conventional biomedical risk factors. These behavioural factors should be studied further in prospective investigations. PMID: 7584801 [PubMed - indexed for MEDLINE]
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| 3. |
- Welin, Catharina, 1945, et al.
(författare)
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Myocardial infarction in relation to work, family and life events
- 1995
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Ingår i: Cardiovascular Risk Factors. - 1130-7501. ; 5:1, s. 30-38
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Tidskriftsartikel (refereegranskat)abstract
- The relationship between psychosocial factors and nonfatal myocardial infarction (MI) was studied by comparing, controlling for traditional risk factors, consecutive male (n=55) patients, who had had a first MI, with a population sample of 283 men and 129 women. All were <65 years of age. The psychosocial factors were investigated by means of a self-administered questionnaire. Men with MI significantly more often did shift work, reported mental strain at work, reported dissatisfaction with their financial situation, and had experienced more negative life events during the last year, compared to controls. Women with MI more often reported mental strain at work and dissatisfaction with their financial situation compared with controls. After controlling for traditional risk factors (smoking, hypertension, serum cholesterol, and diabetes), all factors were still significantly related to MI among men. Among women, only mental strain at work remained significant. However, there were no differences between MI patients and controls in educational level, overtime or extra work, marital status, or other family circumstances. In multivariate analyses including traditional risk factors and all significant psychosocial factors, mental strain at work emerged as an independent risk factor in both sexes, whereas negative life events during the last year was an independent risk factor in men only.
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| 4. |
- Welin, Catharina, 1945, et al.
(författare)
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Social relationships and myocardial infarction: a case-control study.
- 1996
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Ingår i: Journal of Cardiovascular Risk. - 1350-6277. ; 3:2, s. 183-190
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: For more than 10 years there has been increasing evidence that not only biological risk factors are important for the development of coronary heart disease. The present study is one of a series of case-control studies in which a wide range of psychosocial factors in the same population have been analysed to obtain information on their relationship with myocardial infarction, and of the interaction between psychosocial and biomedical variables. METHODS: The association between social relationships and nonfatal myocardial infarction was studied by comparing consecutively admitted male (n = 288) and female (n = 55) patients with myocardial infarction with a population sample of 283 men and 129 women. All participants were under 65 years of age. The social relationships were investigated by means of a self-administered questionnaire. RESULTS: Men with myocardial infarction reported significantly lower perceived emotional support compared with their controls, as well as less social activity. Women with myocardial infarction reported significantly less social activity than their controls. There were no significant differences between cases and controls in social integration (number and frequency of social relationships and contacts). Neither did dissatisfaction with social relationships differ significantly between patients with myocardial infarction and controls. After controlling for traditional risk factors (smoking, hypertension, serum cholesterol level, diabetes) perceived emotional support remained significantly related to myocardial infarction in men, and so did the amount of social activity in both men and women. CONCLUSION: The importance of perceived emotional support and lack of social activity is amplified by the fact that they are related to myocardial infarction independently of conventional biomedical risk factors. These social factors should be studied further in prospective investigations. PMID: 8836861 [PubMed - indexed for MEDLINE]
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