| 1. |
- Biurrun, Idoia, et al.
(författare)
-
Benchmarking plant diversity of Palaearctic grasslands and other open habitats
- 2021
-
Ingår i: Journal of Vegetation Science. - Oxford : John Wiley & Sons. - 1100-9233 .- 1654-1103. ; 32:4
-
Tidskriftsartikel (refereegranskat)abstract
- Journal of Vegetation Science published by John Wiley & Sons Ltd on behalf of International Association for Vegetation Science.Aims: Understanding fine-grain diversity patterns across large spatial extents is fundamental for macroecological research and biodiversity conservation. Using the GrassPlot database, we provide benchmarks of fine-grain richness values of Palaearctic open habitats for vascular plants, bryophytes, lichens and complete vegetation (i.e., the sum of the former three groups). Location: Palaearctic biogeographic realm. Methods: We used 126,524 plots of eight standard grain sizes from the GrassPlot database: 0.0001, 0.001, 0.01, 0.1, 1, 10, 100 and 1,000 m2 and calculated the mean richness and standard deviations, as well as maximum, minimum, median, and first and third quartiles for each combination of grain size, taxonomic group, biome, region, vegetation type and phytosociological class. Results: Patterns of plant diversity in vegetation types and biomes differ across grain sizes and taxonomic groups. Overall, secondary (mostly semi-natural) grasslands and natural grasslands are the richest vegetation type. The open-access file ”GrassPlot Diversity Benchmarks” and the web tool “GrassPlot Diversity Explorer” are now available online (https://edgg.org/databases/GrasslandDiversityExplorer) and provide more insights into species richness patterns in the Palaearctic open habitats. Conclusions: The GrassPlot Diversity Benchmarks provide high-quality data on species richness in open habitat types across the Palaearctic. These benchmark data can be used in vegetation ecology, macroecology, biodiversity conservation and data quality checking. While the amount of data in the underlying GrassPlot database and their spatial coverage are smaller than in other extensive vegetation-plot databases, species recordings in GrassPlot are on average more complete, making it a valuable complementary data source in macroecology. © 2021 The Authors.
|
|
| 2. |
- d'Alessandro, Elisa, et al.
(författare)
-
Thrombo-Inflammation in Cardiovascular Disease : An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis
- 2020
-
Ingår i: Thrombosis and Haemostasis. - : Georg Thieme Verlag KG. - 0340-6245 .- 2567-689X. ; 120:4, s. 538-564
-
Tidskriftsartikel (refereegranskat)abstract
- Thrombo-inflammation describes the complex interplay between blood coagulation and inflammation that plays a critical role in cardiovascular diseases. The third Maastricht Consensus Conference on Thrombosis assembled basic, translational, and clinical scientists to discuss the origin and potential consequences of thrombo-inflammation in the etiology, diagnostics, and management of patients with cardiovascular disease, including myocardial infarction, stroke, and peripheral artery disease. This article presents a state-of-the-art reflection of expert opinions and consensus recommendations regarding the following topics: (1) challenges of the endothelial cell barrier; (2) circulating cells and thrombo-inflammation, focused on platelets, neutrophils, and neutrophil extracellular traps; (3) procoagulant mechanisms; (4) arterial vascular changes in atherogenesis; attenuating atherosclerosis and ischemia/reperfusion injury; (5) management of patients with arterial vascular disease; and (6) pathogenesis of venous thrombosis and late consequences of venous thromboembolism.
|
|
| 3. |
- Demichev, Vadim, et al.
(författare)
-
A time-resolved proteomic and prognostic map of COVID-19
- 2021
-
Ingår i: Cell Systems. - : Elsevier BV. - 2405-4712 .- 2405-4720. ; 12:8, s. 780-794.e7
-
Tidskriftsartikel (refereegranskat)abstract
- COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection to severe organ damage and death. We characterized the time-dependent progression of the disease in 139 COVID-19 inpatients by measuring 86 accredited diagnostic parameters, such as blood cell counts and enzyme activities, as well as untargeted plasma proteomes at 687 sampling points. We report an initial spike in a systemic inflammatory response, which is gradually alleviated and followed by a protein signature indicative of tissue repair, metabolic reconstitution, and immunomodulation. We identify prognostic marker signatures for devising risk-adapted treatment strategies and use machine learning to classify therapeutic needs. We show that the machine learning models based on the proteome are transferable to an independent cohort. Our study presents a map linking routinely used clinical diagnostic parameters to plasma proteomes and their dynamics in an infectious disease.
|
|
| 4. |
- Kleineidam, Luca, et al.
(författare)
-
Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve
- 2022
-
Ingår i: Frontiers in Psychology. - : Frontiers Media SA. - 1664-1078. ; 13
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: Several lifestyle factors promote protection against Alzheimer's disease (AD) throughout a person's lifespan. Although such protective effects have been described for occupational cognitive requirements (OCR) in midlife, it is currently unknown whether they are conveyed by brain maintenance (BM), brain reserve (BR), or cognitive reserve (CR) or a combination of them. Methods: We systematically derived hypotheses for these resilience concepts and tested them in the population-based AgeCoDe cohort and memory clinic-based AD high-risk DELCODE study. The OCR score (OCRS) was measured using job activities based on the O*NET occupational classification system. Four sets of analyses were conducted: (1) the interaction of OCR and APOE-ε4 with regard to cognitive decline (N = 2,369, AgeCoDe), (2) association with differentially shaped retrospective trajectories before the onset of dementia of the Alzheimer's type (DAT; N = 474, AgeCoDe), (3) cross-sectional interaction of the OCR and cerebrospinal fluid (CSF) AD biomarkers and brain structural measures regarding memory function (N = 873, DELCODE), and (4) cross-sectional and longitudinal association of OCR with CSF AD biomarkers and brain structural measures (N = 873, DELCODE). Results: Regarding (1), higher OCRS was associated with a reduced association of APOE-ε4 with cognitive decline (mean follow-up = 6.03 years), consistent with CR and BR. Regarding (2), high OCRS was associated with a later onset but subsequently stronger cognitive decline in individuals converting to DAT, consistent with CR. Regarding (3), higher OCRS was associated with a weaker association of the CSF Aβ42/40 ratio and hippocampal volume with memory function, consistent with CR. Regarding (4), OCR was not associated with the levels or changes in CSF AD biomarkers (mean follow-up = 2.61 years). We found a cross-sectional, age-independent association of OCRS with some MRI markers, but no association with 1-year-change. OCR was not associated with the intracranial volume. These results are not completely consistent with those of BR or BM. Discussion: Our results support the link between OCR and CR. Promoting and seeking complex and stimulating work conditions in midlife could therefore contribute to increased resistance to pathologies in old age and might complement prevention measures aimed at reducing pathology.
|
|
| 5. |
- Newfield, Christopher, et al.
(författare)
-
PART 2: ANTHROPOLOGY, CULTURAL STUDIES AND ORGANISATIONS
- 2023
-
Ingår i: LEARNING AND TEACHING-THE INTERNATIONAL JOURNAL OF HIGHER EDUCATION IN THE SOCIAL SCIENCES. - 1755-2273 .- 1755-2281. ; 16:3, s. 31-55
-
Tidskriftsartikel (refereegranskat)abstract
- Four authors analyse Sue's impact on the discipline of anthropology and on the postgraduates she supervised. They highlight in particular her contributions as a teacher and her advocacy of what she terms 'political reflexivity'.
|
|
| 6. |
- Skoglund, Annika, Docent, 1977-, et al.
(författare)
-
Climate Activism : How Communities Take Renewable Energy Actions Across Business and Society
- 2022
-
Bok (refereegranskat)abstract
- What is activism? The answer is, typically, that it is a form of opposition, often expressed on the streets. Skoglund and Böhm argue differently. They identify forms of 'insider activism' within corporations, state agencies and villages, showing how people seek to transform society by working within the system, rather than outright opposing it. Using extensive empirical data, Skoglund and Böhm analyze the transformation of climate activism in a rapidly changing political landscape, arguing that it is time to think beyond the tensions between activism and enterprise. They trace the everyday renewable energy actions of a growing 'epistemic community' of climate activists who are dispersed across organizational boundaries and domains. This book is testament to a new way of understanding activism as an organizational force that brings about the transition towards sustainability across business and society and is of interest to social science scholars of business, renewable energy and sustainable development.
|
|
| 7. |
- Skoglund, Annika, 1977-, et al.
(författare)
-
Prefigurative Partaking : Employees’ Environmental Activism in an Energy Utility
- 2020
-
Ingår i: Organization Studies. - : SAGE Publications. - 0170-8406 .- 1741-3044. ; 41:9, s. 1257-1283
-
Tidskriftsartikel (refereegranskat)abstract
- The separation between an ‘inside’ and ‘outside’ of organizational politics has become untenable in a rapidly changing political landscape, where people engage in environmental activism in many different domains. To understand contemporary environmental activism, we situate ourselves empirically within an energy utility, Ordalia [pseudonym], a large corporation active across Europe and heavily criticized by external activists for its carbon emitting operations. By merging Rancière’s method of equality and notion of ‘partaking’ with literature on prefiguration in social movements, we analyse everyday green actions pursued by Ordalia’s employees, which we conceptualize as ‘prefigurative partaking’. By focusing on six characterizing themes of prefigurative partaking – aspirational, individual, professional, critical, loyal and communal – we have found that employee activism is incremental, horizontal and boundaryless. We discuss these findings in relation to recent calls for more fruitful exchanges between social movement theory and organization studies, arguing that Rancière’s conceptualization of politics can help us study actions that span civil society and business. This complements and expands our understanding of environmental activism as a dispersed set of actions that can take place anywhere, and hence also at work.
|
|
