Search: (WFRF:(Van den Berg Leonard H.)) pers:(Schelhaas Helenius J.)
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Genetic variation i...
Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis.
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van Es, Michael A (author)
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van Vught, Paul W J (author)
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Blauw, Hylke M (author)
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Franke, Lude (author)
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Saris, Christiaan G J (author)
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Van den Bosch, Ludo (author)
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de Jong, Sonja W (author)
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de Jong, Vianney (author)
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Baas, Frank (author)
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van't Slot, Ruben (author)
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Lemmens, Robin (author)
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Schelhaas, Helenius J (author)
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- Birve, Anna (author)
- Umeå universitet,Neurologi
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Sleegers, Kristel (author)
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Van Broeckhoven, Christine (author)
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Schymick, Jennifer C (author)
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Traynor, Bryan J (author)
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Wokke, John H J (author)
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Wijmenga, Cisca (author)
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Robberecht, Wim (author)
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- Andersen, Peter M (author)
- Umeå universitet,Neurologi
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Veldink, Jan H (author)
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Ophoff, Roel A (author)
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van den Berg, Leonard H (author)
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(creator_code:org_t)
- 2007-12-16
- 2008
- English.
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In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 40:1, s. 29-31
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- We identified a SNP in the DPP6 gene that is consistently strongly associated with susceptibility to amyotrophic lateral sclerosis (ALS) in different populations of European ancestry, with an overall P value of 5.04 x 10(-8) in 1,767 cases and 1,916 healthy controls and with an odds ratio of 1.30 (95% confidence interval (CI) of 1.18-1.43). Our finding is the first report of a genome-wide significant association with sporadic ALS and may be a target for future functional studies.
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- art (subject category)
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- By the author/editor
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van Es, Michael ...
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van Vught, Paul ...
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Blauw, Hylke M
-
Franke, Lude
-
Saris, Christiaa ...
-
Van den Bosch, L ...
-
show more...
-
de Jong, Sonja W
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de Jong, Vianney
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Baas, Frank
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van't Slot, Rube ...
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Lemmens, Robin
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Schelhaas, Helen ...
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Birve, Anna
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Sleegers, Kriste ...
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Van Broeckhoven, ...
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Schymick, Jennif ...
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Traynor, Bryan J
-
Wokke, John H J
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Wijmenga, Cisca
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Robberecht, Wim
-
Andersen, Peter ...
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Veldink, Jan H
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Ophoff, Roel A
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van den Berg, Le ...
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show less...
- Articles in the publication
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Nature genetics
- By the university
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Umeå University