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- Carlsson, Lena, et al.
(author)
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Differences in the distribution of synemin, paranemin, and plectin in skeletal muscles of wild-type and desmin knock-out mice
- 2000
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In: Histochemistry and Cell Biology. - : Springer. - 0948-6143 .- 1432-119X. ; 114:1, s. 39-47
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Journal article (peer-reviewed)abstract
- Mice lacking the gene encoding for the intermediate filament protein desmin have a surprisingly normal myofibrillar organization in skeletal muscle fibers, although myopathy develops in highly used muscles. In the present study we examined how synemin, paranemin, and plectin, three key cytoskeletal proteins related to desmin, are organized in normal and desmin knock-out (K/O) mice. We show that in wild-type mice, synemin, paranemin, and plectin were colocalized with desmin in Z-disc-associated striations and at the sarcolemma. All three proteins were also present at the myotendinous junctions and in the postsynaptic area of motor endplates. In the desmin K/O mice the distribution of plectin was unaffected, whereas synemin and paranemin were partly affected. The Z-disc-associated striations were in general no longer present in between the myofibrils. In contrast, at the myotendinous and neuromuscular junctions synemin and paranemin were still present. Our study shows that plectin differs from synemin and paranemin in its binding properties to the myofibrillar Z-discs and that the cytoskeleton in junctional areas is particularly complex in its organization.
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| 2. |
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| 3. |
- lI, M. X.D., et al.
(author)
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Two-mesh refinement indicators and adaptivity in non-linear explicit finite element analysis of shells using LS-DYNA
- 2000
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In: International Journal for Numerical Methods in Engineering. - 0029-5981 .- 1097-0207. ; 16:11, s. 785-800
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Journal article (peer-reviewed)abstract
- Two-mesh refinement indicators based on the gradients of effective stresses and effective plastic strains, respectively, are proposed for adaptive finite element analysis of the large deformation, materially non-linear dynamic response of shells. The refinement strategy consists of equi-distributing the variation of stresses or plastic strains over the elements of the mesh. A program module for implementing these refinement indicators has been developed and coupled with the general non-linear finite element explicit code LS-DYNA. Numerical examples including both material and geometric non-linearities are presented. It is shown that these indicators can effectively identify those finite elements, which have high gradients of stresses and strains so that the mesh is refined in the region's undergoing the most severe deformations.
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| 4. |
- Nilsson, H, et al.
(author)
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The FERRUM project: new experimental and theoretical f-values for 4p-4d transitions in FeII applied to HST spectra of chi Lupi
- 2000
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In: Astronomy & Astrophysics. - 0004-6361. ; 362:1, s. 410-418
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Journal article (peer-reviewed)abstract
- Radiative lifetimes for six highly excited levels in Fe II have been measured at Lund Laser Centre applying the laser induced fluorescence technique and two-step excitation. The energy levels belong to the even-parity 3d(6)(D-5)(4)d subconfiguration at about 10 eV. Branching fractions (BF:s) of 29 transitions from these levels to the 3d(6)(D-5)4p subconfiguration at about 5 eV have been measured in the wavelength region 2000-3000 Angstrom with the Lund Fourier Transform Spectrometer. By normalizing the BF:s with the lifetimes we get experimental oscillator strengths for these 29 4p-4d lines. The oscillator strengths are compared with new theoretical calculations using the orthogonal operator technique and applied to high-resolution spectra of the star chi Lupi, recorded with the Hubble Space Telescope.
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