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1.
  • Almqvist, Anna-Lena (författare)
  • Expectations relating to childcare among French and Swedish families
  • 2007
  • Ingår i: Community, Work and Family. - : Routledge. - 1366-8803 .- 1469-3615. ; 10:1, s. 17-38
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper investigates how policy and values interrelate concerning expectations of childcare based on 80 interviews with 40 families with young children from France and Sweden, respectively. Upbringing, learning and socialization are important expectations among French parents. The results presented here are in line with educational goals that may have been influenced by policy. The findings suggest that France may, in terms of expectations on childcare, still belong to the conservative cluster as categorized by Esping-Andersen (1990), although family policy may differ from that of, for example, Germany and Italy in the same cluster. Swedish parents stress the importance of the individual child as well as pedagogy, thus, indicating compatibility between a parental wish for the individual development of the child and an emphasis on collective care in Swedish family policy.
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2.
  • Amundadottir, Laufey T., et al. (författare)
  • A common variant associated with prostate cancer in European and African populations
  • 2006
  • Ingår i: Nature Genetics. - DeCODE Genet, IS-101 Reykjavik, Iceland. Univ Iceland, Landspitali Hosp, Dept Pathol, IS-101 Reykjavik, Iceland. Univ Iceland, Landspitali Hosp, Dept Urol, IS-101 Reykjavik, Iceland. Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA. Orebro Univ Hosp, Dept Urol & Clin Med, Orebro, Sweden. Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden. Univ Michigan, Dept Urol, Ann Arbor, MI 48109 USA. Northwestern Univ, Feinberg Sch Med, Dept Urol, Chicago, IL 60611 USA. Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA. Univ Chicago, Dept Human Genet, Chicago, IL 60637 USA. Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA. : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 38:6, s. 652-658
  • Tidskriftsartikel (refereegranskat)abstract
    • With the increasing incidence of prostate cancer, identifying common genetic variants that confer risk of the disease is important. Here we report such a variant on chromosome 8q24, a region initially identified through a study of Icelandic families. Allele -8 of the microsatellite DG8S737 was associated with prostate cancer in three case-control series of European ancestry from Iceland, Sweden and the US. The estimated odds ratio (OR) of the allele is 1.62 (P = 2.7 x 10(-11)). About 19% of affected men and 13% of the general population carry at least one copy, yielding a population attributable risk (PAR) of approximately 8%. The association was also replicated in an African American case-control group with a similar OR, in which 41% of affected individuals and 30% of the population are carriers. This leads to a greater estimated PAR (16%) that may contribute to higher incidence of prostate cancer in African American men than in men of European ancestry.
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3.
  • Andersson, Per, et al. (författare)
  • Knowledge about cardiovascular risk factors among obese individuals.
  • 2006
  • Ingår i: European Journal of Cardiovascular Nursing. - : Oxford University Press (OUP). - 1474-5151 .- 1873-1953. ; 5:4
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Obesity is an important biological risk factor for cardiovascular disease (CVD).AIMS: The main aim of this study was to answer the question whether obese individuals differ from individuals with normal weight with regard to knowledge about risk factors for CVD. A further aim was to replicate previous findings that obese individuals are at higher risk of developing other biological risk factors for CVD.METHOD: Normal weights, BMI<25 kg/m(2) (n=385), and obese, BMI> or =30 kg/m(2) (n=159), individuals were identified from a screening program conducted among 50-year-old inhabitants of the County of Västmanland, Sweden. Participants answered questions regarding their gender, level of education, and items relating to knowledge about cardiovascular risk factors. Total cholesterol and blood glucose levels, height, weight and blood pressure were measured.RESULTS: Obese individuals did not differ significantly from individuals with a normal weight regarding knowledge of cardiovascular risk factors when education was controlled for. Obesity and low level of education are associated with other risk factors for CVD such as high blood pressure and high serum cholesterol.CONCLUSION: Obese individuals are at an increased risk of developing other risk factors for CVD but are just as knowledgeable about risk factors for CVD as normal weighting individuals.
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4.
  • Andersson, Per, et al. (författare)
  • Lags in behavioral change : A population based comparison of cardiovascular risk behavior in Poland and Sweden.
  • 2006
  • Ingår i: Central European Journal of Public Health. - : National Institute of Public Health. - 1210-7778 .- 1803-1048. ; 14:2
  • Tidskriftsartikel (refereegranskat)abstract
    • One thousand and twenty Polish men and women and 1,011 Swedish men and women aged 50 and recruited through primary health care took part in a survey relating to their knowledge of health-related behaviour, attitudes to health-related behaviour and self-reported risk behaviour. The results reveal that Poles know as much about cardiovascular risk factors as Swedes, but that Swedes feel that it is more important to change their dietary habits and to influence factors in the working environment to avoid the risk of developing CVD than did Poles. Swedes also displayed less risk behaviour than Poles and more Swedes than Poles had successfully stopped smoking. These findings suggest that differences in stages of health-related behavior that have previously been observed at an individual level may sometimes also be discerned at a national level.
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7.
  • Brown, David A, et al. (författare)
  • Macrophage inhibitory cytokine 1 : a new prognostic marker in prostate cancer.
  • 2009
  • Ingår i: Clinical Cancer Research. - : AMER ASSOC CANCER RESEARCH. - 1078-0432 .- 1557-3265. ; 15:21, s. 6658-6664
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: High serum levels of macrophage inhibitory cytokine 1 (MIC-1) are strongly associated with metastatic prostate cancer, suggesting MIC-1 is a biomarker for prostate cancer prognosis. EXPERIMENTAL DESIGN: We conducted a prospective cohort study of 1,442 Swedish men with a pathologically verified diagnosis of prostate cancer between 2001 and 2003. Blood was drawn either pretreatment (n = 431) or posttreatment (n = 1,011) and cases were followed for a mean time of 4.9 years (range, 0.1-6.8 years). RESULTS: MIC-1 serum levels independently predicted poor cancer-specific survival with an almost 3-fold higher cancer death rate in patients with serum levels in the highest quartile compared with men with serum levels in the lowest quartile (adjusted hazard ratio, 2.98; 95% confidence interval, 1.82-4.68). Pretreatment MIC-1 levels revealed an even stronger association with disease outcome with an 8-fold higher death rate in the highest compared with the lowest category (adjusted hazard ratio, 7.98; 95% confidence interval, 1.73-36.86). Among patients considered to have localized disease, MIC-1 significantly increased the discriminative capacity between indolent and lethal prostate cancer compared with the established prognostic markers clinical stage, pathologic grade, and prostate-specific antigen level (P = 0.016). A sequence variant in the MIC-1 gene was associated with decreased MIC-1 serum levels (P = 0.002) and decreased prostate cancer mortality (P = 0.003), suggesting a causative role of MIC-1 in prostate cancer prognosis. CONCLUSIONS: Serum MIC-1 concentration is a novel biomarker capable of predicting prostate cancer prognosis.
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8.
  • Carlsson, Linus, 1972-, et al. (författare)
  • A note on B-envelope of holomorphy and B-extendable domains
  • 2008
  • Ingår i: Complex Variables and Elliptic Equations. - Abingdon, Oxon, UK : Taylor & Francis. - 1747-6933 .- 1747-6941. ; 53:4, s. 307-309
  • Tidskriftsartikel (refereegranskat)abstract
    • Let B subset of H(infinity)(X) be a Banach Algebra on a Riemann domain X over C(n). We show that under certain conditions on B and X, all functions in B can be extended to functions in B(E(B, X)) where E(B, X) is the B-envelope of holomorphy.
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10.
  • Carlsson, Linus, 1972- (författare)
  • Ideals and boundaries in Algebras of Holomorphic functions
  • 2006
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • We investigate the spectrum of certain Banach algebras. Properties like generators of maximal ideals and generalized Shilov boundaries are studied. In particular we show that if the ∂-equation has solutions in the algebra of bounded functions or continuous functions up to the boundary of a domain D ⊂⊂ Cn then every maximal ideal over D is generated by the coordinate functions. This implies that the fibres over D in the spectrum are trivial and that the projection on Cn of the n − 1 order generalized Shilov boundary is contained in the boundary of D.For a domain D ⊂⊂ Cn where the boundary of the Nebenhülle coincide with the smooth strictly pseudoconvex boundary points of D we show that there always exist points p ∈ D such that D has the Gleason property at p.If the boundary of an open set U is smooth we show that there exist points in U such that the maximal ideals over those points are generated by the coordinate functions.An example is given of a Riemann domain, Ω, spread over Cn where the fibers over a point p ∈ Ω consist of m > n elements but the maximal ideal over p is generated by n functions.
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