| 1. |
- Martin-Boglind, Lene, et al.
(author)
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The effect of topical antiglaucoma drugs on the results of high-pass resolution perimetry
- 1991
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In: American Journal of Ophthalmology. - 0002-9394 .- 1879-1891. ; 11:6, s. 711-714
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Journal article (peer-reviewed)abstract
- We conducted a randomly assigned, double-masked, crossover study of the effects of betaxolol, epinephrine, pilocarpine, and timolol on the high-passresolution perimetry results in normal subjects. The influence of topical administration of these intraocular pressure reducing drugs was negligible, which confirmed the reliability of high-pass resolution perimetry results. The method seems appropriate for the diagnosis of glaucoma and the follow-up ofpatients with glaucoma.
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| 2. |
- Frisén, Lars, 1939
(author)
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High-pass resolution perimetry and age-related loss of visual pathway neurons.
- 1991
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In: Acta ophthalmologica. - 0001-639X. ; 69:4, s. 511-5
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Journal article (peer-reviewed)abstract
- The normal, age-related decline of results of high-pass resolution perimetry (HRP) predicts a loss of approximately 9,000 retino-cortical neural channels per year of age, or about 1 channel each hour. Previously published counts of numbers of neurons in the optic nerve indicate a loss of approximately 5,000 neurons per year. The HRP results can be accounted for by postulating that neurons are lost at the same rate also in the geniculo-striate visual pathway.
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| 3. |
- Blazynski, C, et al.
(author)
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Adenosine in vertebrate retina : localization, receptor characterization, and function
- 1991
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In: Cellular and Molecular Neurobiology. - 0272-4340. ; 11:5, s. 463-484
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Journal article (peer-reviewed)abstract
- 1. The uptake of [3H] adenosine into specific populations of cells in the inner retina has been demonstrated. In mammalian retina, the exogenous adenosine that is transported into cells is phosphorylated, thereby maintaining a gradient for transport of the purine into the cell. 2. Endogenous stores of adenosine have been demonstrated by localization of cells that are labeled for adenosine-like immunoreactivity. In the rabbit retina, certain of these cells, the displaced cholinergic, GABAergic amacrine cells, are also labeled for adenosine. 3. Purines are tonically released from dark-adapted rabbit retinas and cultured embryonic chick retinal neurons. Release is significantly increased with K+ and neurotransmitters. The evoked release consists of adenosine, ATP, and purine metabolites, and while a portion of this release is Ca2+ dependent, one other component may occur via the bidirectional purine nucleoside transporter. 4. Differential distributions of certain enzymes involved in purine metabolism have also been localized to the inner retina. 5. Heterogeneous distributions of the two subtypes of adenosine receptors, A1 and A2, have been demonstrated in the mammalian retina. Coupling of receptors to adenylate cyclase has also been demonstrated. 6. Adenosine A1 receptor agonists significantly inhibit the K(+)-stimulated release of [3H]-acetylcholine from the rabbit retina, suggesting that endogenous adenosine may modulate the light-evoked or tonic release of ACh.
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| 4. |
- Martin-Boglind, Lene
(author)
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High-pass resolution perimetry in uncomplicated myopia
- 1991
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In: Acta Ophthalmologica Scandinavica. - 1395-3907 .- 1600-0420. ; 69:4, s. 516-520
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Journal article (peer-reviewed)abstract
- Fifteen subjects (28 eyes) with uncomplicated myopia (3-9 D) were examined using high-pass resolution and Goldmann perimetry. In the central 30 degree field a slight increase was observed in mean resolution threshold significantly correlated to the degree of myopia. In the Goldmann visual fields threshold increase was observed in the area around the blind spot in eight subjects (10 eyes). In the resolution fields only one subject (one eye) showed a corresponding abnormality.
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| 5. |
- Scott, Rolene, et al.
(author)
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A preliminary investigation into the direct measurement of intra-ocular light scatter after radial keratotomy
- 1991
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In: Clinical and experimental optometry. - : Wiley-Blackwell. - 0816-4622 .- 1444-0938. ; 74:6, s. 204-209
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Journal article (peer-reviewed)abstract
- A glare score based on intra-ocular light scatter and a questionnaire-based subjective assessment of glare were determined for 18 patients who had undergone radial keratotomy (RK) two weeks to 27 months previously. Results were compared to those of 15 control subjects. T-tests showed no significant difference in glare experienced under photopic conditions by RK patients and control subjects. There was no systematic relationship between glare scores and the subjective assessment of glare, nor between glare scores or subjective assessment of glare and the time which had elapsed since surgery. However, a weak relationship (r2=0.36) was found between glare scores and absolute refractive error. It was concluded that RK did not produce significant levels of intra-ocular light scatter under photopic conditions (155 lux).
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