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- Drin, Iryna, et al.
(författare)
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МАТЕМАТИЧНА МОДЕЛЬ ГЛОБАЛЬНОГО ЕКОНОМІЧНОГО ПРОЦЕСУ З НЕЛОКАЛЬНИМИ УМОВАМИ : [Mathematical model of global economic process with non-local conditions]
- 2018
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Ingår i: Bulletin of the Chernivtsi Trade and Economic Institute. - Chernivtsi : Chtei Knteu. - 2310-8185 .- 2414-5831. ; :1-2, s. 152-158
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Tidskriftsartikel (refereegranskat)abstract
- The essence of dynamic economic behavior of competing economic entities, which simulated nonlocal problem for systems of differential equations with variable coefficients is revealed. Developed a dynamic mathematical model assuming that total production is determined by the following factors: the number of products each side, changing certain equipment, which leads to changes in output, the degree of distrust of competitors, and assuming that the rate of change in output proportional to these factors. A partial case of such a model is the model of the arms race. The economic interpretation of nonlocal conditions is that the production volumes at different times governed by predetermined condition. A mathematical model designed to study the dynamics of the economic process of adjusting production volumes at different times.
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- Sukhin, V. S., et al.
(författare)
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The investigation of PD-L1 expression as a prognostic marker for uterine sarcoma
- 2018
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Ingår i: Морфологія. - : SE Dnipropetrovsk Medical Academy of Health Ministry of Ukraine. - 1997-9665. ; 12:2, s. 62-71
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Tidskriftsartikel (refereegranskat)abstract
- Background: The uterine sarcoma is a rare tumor with the unpredictable, aggressive clinical behavior. Medical science relies on the development of reliable tumor markers, on the basis of which the optimal treatment program can be chosen, and will be also possible to make a prognosis. The hyperexpression of PD-L1 in many cases correlates with unfavorable prognosis of the disease and is an important prognostic biomarker for some types of tumors: melanoma, kidney cancer, non-small cell lung cancer. The role of PD-L1 expression, as a tumor marker in sarcoma, remains unclear. Objective. The investigation of PD-L1 expression as a prognostic tumor marker for uterine sarcoma.Methods: There have been selected 30 uterine sarcoma patients stage I-II (T1-2NxM0), for immunohistochemistry analyze of PD-L1 expression. Depending on the morphological tumor types all the patients were distributed: leiomyosarcoma (LMS) - 20.0%, endometrial stromal sarcoma (ESS) - 46.7%, undifferentiated sarcoma (HC) - 33.3%.Results: Our results showed that 73.3 % of patients with uterine sarcoma exhibited low expression level of PD-L1. The moderate level and overexpression of PD-L1 were observed in undifferentiated and endometrial stromal sarcoma - 13.3 and 6.7 %, respectively. At further follow-up of patients with PD-L1 expression, the relapse of the disease was detected in 50.0 % of cases.Conclusion: The PD-L1 expression in tumor tissue, regardless of its level, is considered to be an unfavorable prognostic factor for uterine sarcoma patients. In case of moderate expression level of PD-L1, so as at its overexpression, the tumor progression was detected in 83.3% of uterine sarcoma patients.
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- Slipchenko, K. V., et al.
(författare)
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Особливості формування структури та фазового складу в процесі реакційного спікання кубічного нітриду бору зі сполуками Ti, Cr, V
- 2018
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Ingår i: Metallofizika i Noveishie Tekhnologii. - : National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka). - 1024-1809. ; 40:8, s. 1081-1091
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Tidskriftsartikel (refereegranskat)abstract
- Influence of sintering temperature on both phase composition and structure of ceramic matrix composites based on cubic boron nitride with binders in a form of Al and the Ti, Cr, V carbides are investigated by methods of physical materials science. As the object of study, three cBN–TiC–Al, cBN–Cr3C2–Al, cBN–VC–Al compositions containing 60% vol. cBN are selected. The composites are obtained by high-pressure high-temperature (HPHT) sintering in high-pressure apparatus AVTT-30 in the temperature range of 1600– 2450°C under pressure of 7.7 GPa. In the process of HPHT sintering of composites in the cBN–TiC–Al and cBN–Cr3C2–Al systems, the formation of titanium and chromium diborides is found at the temperatures of sintering Тsint ≥ 1850°С and Тsint ≥ 2150°С, respectively, simultaneously with the formation of alu-minium nitride.
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