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- Iacobaeus, Christian, et al.
(författare)
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A novel portal imaging device for advanced radiation therapy
- 2001
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Ingår i: Nuclear Science, IEEE Transactions on. - Nuclear Science, IEEE Transactions on : Institute of Electrical and Electronics Engineers (IEEE). - 0018-9499 .- 1558-1578. ; 48:4, Part 2, s. 1496-1502
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Tidskriftsartikel (refereegranskat)
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- Mårtensson, Mattias, et al.
(författare)
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Assessment of left ventricular volumes using simplified 3-D echocardiography and computed tomography - a phantom and clinical study
- 2008
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Ingår i: Cardiovascular Ultrasound. - : Springer Science and Business Media LLC. - 1476-7120. ; 6
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To compare the accuracy of simplified 3-dimensional (3-D) echocardiography vs. multi-slice computed tomography (MSCT) software for the quantification of left ventricular (LV) volumes. Design: Three-D echocardiography (3-planes approach) and MSCT-CardIQ software were calibrated by measuring known volumes of 10 phantoms designed to closely mimic blood-endocardium interface. Subsequently, LV volumes were measured with both the methods in 9 patients referred routinely for coronary angiography and the agreement between the measurements was evaluated. Results: Simplified 3D-echocardiography provided higher degree of agreement between the measured and true phantom volumes (mean difference 0 +/- 1 ml, variation range + 4 to -4 ml) than MSCT software (mean difference 6 +/- 5 ml; variation range + 22 to -10 ml). The agreement between LV measurements in the patients was considerably poorer, with significantly larger volumes produced by MSCT (mean difference - 23 +/- 40 ml, variation between + 93 and -138 ml). Conclusion: Simplified 3-D echocardiography provides more accurate assessment of phantom volumes than MSCT-CardIQ software. The discrepancy between the results of LV measurements with the two methods is even greater and does not warrant their interchangeable diagnostic use.
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- Chiari, Lorenzo, et al.
(författare)
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Audio-biofeedback for balance improvement: an accelerometry-based system.
- 2005
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Ingår i: IEEE Transactions on Biomedical Engineering. - 0018-9294 .- 1558-2531. ; 52:12, s. 2108-11
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Tidskriftsartikel (refereegranskat)abstract
- This paper introduces a prototype audio-biofeedback system for balance improvement through the sonification using trunk kinematic information. In tests of this system, normal healthy subjects performed several trials in which they stood quietly in three sensory conditions while wearing an accelerometric sensory unit and headphones. The audio-biofeedback system converted in real-time the two-dimensional horizontal trunk accelerations into a stereo sound by modulating its frequency, level, and left/right balance. Preliminary results showed that subjects improved balance using this audio-biofeedback system and that this improvement was greater the more that balance was challenged by absent or unreliable sensory cues. In addition, high correlations were found between the center of pressure displacement and trunk acceleration, suggesting accelerometers may be useful for quantifying standing balance.
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- Ahlström, Christer, et al.
(författare)
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Heart sound cancellation from lung sound recordings using recurrence time statistics and nonlinear prediction
- 2005
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Ingår i: IEEE Signal Processing Letters. - : Institutionen för medicinsk teknik. - 1070-9908 .- 1558-2361. ; 12:12, s. 812-815, s. 812-815
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Tidskriftsartikel (refereegranskat)abstract
- Heart sounds (HS) obscure the interpretation of lung sounds (LS). This letter presents a new method to detect and remove this undesired disturbance. The HS detection algorithm is based on a recurrence time statistic that is sensitive to changes in a reconstructed state space. Signal segments that are found to contain HS are removed, and the arising missing parts are replaced with predicted LS using a nonlinear prediction scheme. The prediction operates in the reconstructed state space and uses an iterated integrated nearest trajectory algorithm. The HS detection algorithm detects HS with an error rate of 4% false positives and 8% false negatives. The spectral difference between the reconstructed LS signal and an LS signal with removed HS was 0.34/spl plusmn/0.25, 0.50/spl plusmn/0.33, 0.46/spl plusmn/0.35, and 0.94/spl plusmn/0.64 dB/Hz in the frequency bands 20-40, 40-70, 70-150, and 150-300 Hz, respectively. The cross-correlation index was found to be 99.7%, indicating excellent similarity between actual LS and predicted LS. Listening tests performed by a skilled physician showed high-quality auditory results.
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- Angelopoulos, Angelos, et al.
(författare)
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Physics at CPLEAR
- 2003
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Ingår i: Physics Reports. - : Elsevier. ; 374:3, s. 165-270
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Tidskriftsartikel (refereegranskat)abstract
- LEAR offered unique opportunities to study the symmetries which exist between matter and antimatter. At variance with other approaches at this facility, CPLEAR was an experiment devoted to the study of CP, T and CPT symmetries in the neutral-kaon system. A variety of measurements allowed us to determine with high precision the parameters which describe the time evolution of the neutral kaons and their antiparticles, including decay amplitudes, and the related symmetry properties. Limits concerning quantum-mechanical predictions (EPR, coherence of the wave function) or the equivalence principle of general relativity have been obtained. An account of the main features of the experiment and its performances is given here, together with the results achieved.
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- Eriksson, Thomas, et al.
(författare)
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Influence of medial collagen organization and in-situ axial stretch on saccular cerebral aneurysm growth
- 2009
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Ingår i: Journal of Biomechanical Engineering. - : ASME International. - 0148-0731 .- 1528-8951. ; 131:10
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Tidskriftsartikel (refereegranskat)abstract
- A model for saccular cerebral aneurysm growth, proposed by Kroon and Holzapfel (2007, "A Model for Saccular Cerebral Aneurysm Growth in a Human Middle Cerebral Artery," J. Theor. Biol., 247, pp. 775-787; 2008, "Modeling of Saccular Aneurysm Growth in a Human Middle Cerebral Artery," ASME J. Biomech. Eng., 130, p. 051012), is further investigated. A human middle cerebral artery is modeled as a two-layer cylinder where the layers correspond to the media and the adventitia. The immediate loss of media in the location of the aneurysm is taken to be responsible for the initiation of the aneurysm growth. The aneurysmis regarded as a development of the adventitia, which is composed of several distinct layers of collagen fibers perfectly aligned in specified directions. The collagen fibers are the only load-bearing constituent in the aneurysm wall; their production and degradation depend on the stretch of the wall and are responsible for the aneurysm growth. The anisotropy of the surrounding media was modeled using the strain-energy function proposed by Holzapfel et al. (2000, "A New Constitutive Framework for Arterial Wall Mechanics and a Comparative Study of Material Models," J. Elast., 61, pp. 1-48), which is valid for an elastic material with two families of fibers. It was shown that the inclusion of fibers in the media reduced the maximum principal Cauchy stress and the maximum shear stress in the aneurysm wall. The thickness increase in the aneurysm wall due to material growth was also decreased. Varying the fiber angle in the media from a circumferential direction to a deviation of 10 deg from the circumferential direction did, however, only show a little effect. Altering the axial in situ stretch of the artery had a much larger effect in terms of the steady-state shape of the aneurysm and the resulting stresses in the aneurysm wall. The peak values of the maximum principal stress and the thickness increase both became significantly higher for larger axial stretches.
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