| 1. |
- Aspenberg, Per, et al.
(författare)
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Fibroblast growth factor stimulates bone formation bone induction studied in rats
- 1989
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Ingår i: Acta Orthopaedica. - : Medical Journals Sweden AB. - 1745-3674 .- 0001-6470. ; 60:4, s. 473-476
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Tidskriftsartikel (refereegranskat)abstract
- Implantation of demineralized bone matrix in rodents elicits a series of cellular events leading to the formation of new bone inside and adjacent to the implant. This process is believed to be initiated by an inductive protein present in bone matrix. It has been suggested that local growth factors may further regulate the process once it has been initiated. This investigation was designed to study the effect of adding a growth factor to the inductive implant. Pairs of demineralized rat femoral diaphyses were implanted intramuscularly in rats. the marrow canal of one implant in each pair was filled with a carboxymethyl cellulose gel containing 75 ng of recombinant human basic fibroblast growth factor (FGF). the other implant in each pair served as a control. It was either filled with the gel without FGF or left untreated. Bone formation was induced by all the implants after 3 weeks. the amount of mineralized tissue in the FGF-treated implants was 25 percent greater than in untreated controls. the carboxymethyl cellulose gel alone did not affect the bone yield.
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| 2. |
- Aspenberg, Per, et al.
(författare)
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Rabbit bone matrix induces bone formation in the athymic rat
- 1988
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Ingår i: Acta Orthopaedica. - : Medical Journals Sweden AB. - 1745-3674 .- 0001-6470. ; 59:3, s. 276-278
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Tidskriftsartikel (refereegranskat)abstract
- Rabbit and rat bone matrix were implanted in athymic rat muscle, and the bone yield was measured as total calcium content after 4, 6, and 8 weeks. Matrix from both species induced equal amounts of new bone in the athymic rat. In rabbit and normal rat, the xenogenic matrix induced little or no bone formation. Thus, in the case of rabbit and rat, bone induction is species specific due to immunogenic mechanisms. the athymic rat can be used to measure inductive properties of bone matrix from different species.
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| 3. |
- Bengnér, Urban, et al.
(författare)
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Epidemiology of ankle fracture 1950 and 1980. Increasing incidence in elderly women
- 1986
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 57:1, s. 35-37
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Tidskriftsartikel (refereegranskat)abstract
- During 1980-82, 739 ankle fractures occurred in Malmo. These were compared with 383 ankle fractures occurring in 1950-52. In men there was an increase in the age-specific incidence up to the age of 60, especially in fractures of the lateral malleolus. In women there was an increase in the age-specific incidence above the age of 50, both in lateral malleolar fractures and, even more pronounced, in bi- and tri- malleolar fractures.
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| 4. |
- Bengnér, Urban, et al.
(författare)
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Increasing incidence of tibia condyle and patella fractures
- 1986
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 57:4, s. 334-336
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Tidskriftsartikel (refereegranskat)abstract
- The age and sex specific incidence of tibial condyle fractures and patellar fractures were compared between 1950-55 and 1980-83 in the urban population of Malmo. In elderly women there was an increased incidence over these 30 years for both fracture types.
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| 5. |
- Brorson, Håkan, et al.
(författare)
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Normal pinch strength.
- 1989
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Ingår i: Acta Orthopaedica Scandinavica. - 0001-6470. ; 60:1, s. 66-68
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Tidskriftsartikel (refereegranskat)abstract
- The normal pinch strength was determined with the Mannerfelt-Ulrich intrinsic meter in 90 men and women aged 21-65 years. The pinch strength decreased with increasing age. The ratio dominant/nondominant hand was 1.12, 0.13 (mean, SD) for both men and women. The ratio would be useful in evaluating pinch strength under pathologic conditions.
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| 6. |
- Bylander, Birger, et al.
(författare)
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Stapling for tibial-growth deformity : A case report on roentgen stereophotogrammetric analysis
- 1989
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Ingår i: Acta Orthopaedica. - : Medical Journals Sweden AB. - 1745-3674 .- 0001-6470. ; 60:4, s. 487-490
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Tidskriftsartikel (refereegranskat)abstract
- A 9-year-old boy sustained a Salter-Harris Type IV fracture in the proximal tibia. the injury resulted in a progressive valgus deformity, detected already after 3 months by roentgen stereophotogrammetry. After temporary stapling medially, the growth rate increased laterally and the deformity was corrected. Unilateral stapling is an alternative procedure for correcting angular deformity following a physeal injury.
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| 7. |
- Edwards, Birgitta, et al.
(författare)
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Patellar fractures. A 30-year follow-up
- 1989
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 60:6, s. 712-714
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Tidskriftsartikel (refereegranskat)abstract
- Forty patients who had had a patellar fracture during the years 1950-58 were reevaluated 30 years later. A clinical and radiographic examination was performed. Fourteen patients had subjective complaints. Two thirds of the patients who had more than 2-mm diastasis or 1-mm incongruity had complaints and reduced quadriceps strength. Radiographically, all the patients had a reduction in the lateral patellofemoral distance in the axial view with the greatest reduction in the knees with diastasis or incongruity of the fracture.
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| 8. |
- Grubb, A
(författare)
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Safer proteinase treatment of sciatica. A biochemical preview of chymopapain inhibitors
- 1988
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 59:1, s. 63-65
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Forskningsöversikt (refereegranskat)abstract
- As pointed out in the preceding review (Nachemson and Rydevik 1988), the most serious and common complications of chymopapain treatment of patients with sciatica due to disc herniation are cerebral or subarachnoid hemorrhages and allergic manifestations. Recent progress in biochemical and physiologic studies of cysteine proteinases and their inhibitors allows some speculation on how these complications in the future might be alleviated or avoided and on how the efficiency of proteinase treatment of patients with sciatica might be increased.
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| 9. |
- Hägglund, Gunnar, et al.
(författare)
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A case of bilateral duplication of the patella
- 1989
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Ingår i: Acta Orthopaedica. - : Medical Journals Sweden AB. - 1745-3674 .- 0001-6470. ; 60:6, s. 725-727
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Tidskriftsartikel (refereegranskat)abstract
- A boy with bilateral duplication of his patellae was radiographically examined between 8 and 11 years of age. the duplication was probably caused by a disrupted fusion of two ossification centra.
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| 10. |
- Hägglund, Gunnar, et al.
(författare)
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Growth of children with physiolysis of the hip
- 1987
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Ingår i: Acta Orthopaedica. - : Medical Journals Sweden AB. - 1745-3674 .- 0001-6470. ; 58:2, s. 117-120
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Tidskriftsartikel (refereegranskat)abstract
- Growth during adolescence was analyzed in 40 children with slipped capital femoral epiphysis using the Infancy Childhood Puberty growth model. the advantage of this model is that reference values for height can be adjusted for the individual age at pubertal maturation. In both sexes an above average height was found before the onset of the pubertal growth spurt. However, the pubertal gain in height was less than normal, and at maturity the heights were only slightly above the reference mean values. Most of the children had their first hip symptoms during the period of increasing gain in height at the initial stage of the pubertal growth spurt. Both boys and girls were overweight before puberty and remained so during puberty and at maturity.
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