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- Segelmark, M., et al.
(författare)
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ANCA and IgG subclasses
- 1993
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Ingår i: ANCA-Associated Vasculitides : Immunological and Clinical Aspects - Immunological and Clinical Aspects. - 0065-2598. - 9781475791846 ; 336, s. 71-75
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Bokkapitel (refereegranskat)abstract
- We studied IgG subclass distribution of ANCA in 247 patients with ELISA. We used monoclonal subclass specific antibodies and purified MPO and proteinase 3 as antigen. We found that IgG1 and IgG4 yield high values in both groups. We also found that high IgG2 titers were rare among the anti-proteinase 3 positive, while it was common among anti-MPO sera. In the assays for IgG3 the situation was the opposite.
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