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- Ask, Per, et al.
(författare)
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Accuracy and choice of procedures in 24-hour oesophageal pH monitoring with monocrystalline antimony electrodes.
- 1986
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Ingår i: Medical and Biological Engineering and Computing. - 0140-0118 .- 1741-0444. ; 24:6, s. 602-608
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Tidskriftsartikel (refereegranskat)abstract
- In 24 h pH monitoring, the evaluation is dependent on the absolute accuracy of the pH measurements. Several sources of error exist, such as the chemical composition of calibration buffers and reference electrode gel and the effect of temperature on both the pH and the reference electrodes. We investigated the magnitude of these errors for the monocrystalline antimony electrode. Similar analysis applies to other types of pH electrodes. The errors we found are important when choosing a calibration procedure. We recommend a calibration procedure in which the pH and reference electrodes are both put in a beaker with the calibration buffers prior to and after the 24 h measurements. The calibration buffers and the electrode gel should have a specially selected ion composition where, for example, the Cl-ion concentration is critical. Corrections for differences in temperature between the calibration and the in situ measurements must be added. The pH measurements can be checked by performing in situ calibration.
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- Ask, Per, et al.
(författare)
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Combined pH and pressure measurement device for oesophageal investigations.
- 1981
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Ingår i: Medical and Biological Engineering and Computing. - 0140-0118 .- 1741-0444. ; 19:4, s. 443-446
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Tidskriftsartikel (refereegranskat)abstract
- A combined pH- and pressure-measurement device for oesophageal investigations has been designed using monocrystalline antimony pH electrodes and perfused polyvinyl catheters. The combined device facilitates pressure measurements simultaneously with pH recording, both distal and proximal to the pH electrode. The device is easier to pass through the nose to the oesophagus than the conventional glass pH electrode. pH and pressure measurements in the oesophagus are therefore simplified and valuable information about the function of the region of the lower oesophageal sphincter is added owing to the simultaneous recording of the two parameters.
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5. |
- Ask, Per, et al.
(författare)
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On the use of monocrystalline antimony pH electrodes in gastro-oesophageal functional disorders.
- 1982
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Ingår i: Medical and Biological Engineering and Computing. - 0140-0118 .- 1741-0444. ; 20:3, s. 383-389
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Tidskriftsartikel (refereegranskat)abstract
- Monocrystalline antimony electrodes have been shown to be suitable for thein vivo determination of pH in blood, tissue and in the upper gastro-intestinal canal. Thanks to their small dimensions it has been possible to mount them into conventional manometry catheters for oesophageal investigation. The monocrystalline antimony pH electrode has several advantages over the conventional pH glass electrode; better accuracy, shorter rise time, smaller dimensions. The monocrystalline antimony electrode has been used for long-term registration of gastro-oesophageal reflux, for the oesophageal acid clearing test and for identification of the pH gradient zone between the gastric and oesophageal mucosa. Its use in combination with pressure sensors has added a new dimension to the diagnosis of functional disorders in the gastro-oesophageal region.
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9. |
- Larsby, Birgitta, et al.
(författare)
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Quantification of the vestibulo-ocular reflex and visual-vestibular interaction for the purpose of clinical diagnosis
- 1982
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Ingår i: Medical and Biological Engineering and Computing. - : Kluwer Academic Publishers. - 0140-0118 .- 1741-0444. ; 20:1, s. 99-107
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Tidskriftsartikel (refereegranskat)abstract
- Pseudorandom vestibular rotatory stimuli covering the normal head movement range (0–6 Hz) and power spectrum analysis techniques are used to clinically evaluate the vestibulo-ocular reflex (v.o.r.). Measurements of compensatory eye movements are recorded during fixation of a stationary target, during fixation of a target moving with the subject and in darkness. The gain above 3 Hz quantifies vestibular function under all these conditions. A frequency-dependent v.o.r. asymmetry indicates the side of a peripheral lesion. The fixation suppression curve at medium frequencies quantifies visual-vestibular interaction. Thus the new test is a powerful diagnostic tool applicable to disease of the labyrinth and central vestibular pathways. This test is evaluated on monkeys before unilateral labyrinthectomy and for an extended period of time after.
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