| 1. |
- Sundgren, Mathias, et al.
(författare)
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Cognitive Impairment Has a Strong Relation to Nonsomatic Symptoms of Depression in RelapsingRemitting Multiple Sclerosis
- 2013
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Ingår i: Archives of clinical neuropsychology. - : Oxford University Press (OUP). - 0887-6177 .- 1873-5843. ; 28:2, s. 144-155
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Tidskriftsartikel (refereegranskat)abstract
- It is unclear how cognitive impairment in multiple sclerosis (MS) is influenced by physical disability, fatigue, and depression. Our aim was to identify the strongest clinical predictors for cognitive impairment in relapsing-remitting MS (RRMS) patients. The clinical risk factors included in the analysis were physical disability (EDSS), fatigue (FSS), the somatic and nonsomatic components of depression (BDI), disease progression rate [Multiple Sclerosis Severity Score (MSSS)], and psychotropic medication. Cognitive impairment had a prevalence of 30.5% in patients affecting preferentially attention, executive functions, processing speed and visual perception/organization. MSSS was not associated with cognitive impairment, depression, or fatigue. In regression models, cognitive performance was best predicted by the nonsomatic symptoms of depression alone or in combination with physical disability. Exclusion of patients with any psychotropic medication did not influence the results. Our results underscore the importance of evaluating depressive symptoms when suspecting cognitive impairment in patients with RRMS.
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| 2. |
- Wehling, Eike, et al.
(författare)
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Unawareness of olfactory dysfunction and its association with cognitive functioning in middle aged and old adults
- 2011
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Ingår i: Archives of clinical neuropsychology. - : Oxford University Press. - 0887-6177 .- 1873-5843. ; 26:3, s. 260-269
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this study was (a) to investigate the accordance of self-reported and objectively assessed olfactory functioning and (b) to compare performance on cognitive tests of individuals unaware of their olfactory dysfunction with individuals aware of their olfactory status. Two hundred forty participants, constituting two age groups, were evaluated with the Scandinavian Odor Identification Test, a question of self-evaluated olfactory function, tests of cognitive function, and a memory questionnaire. The proportion of individuals being unaware of an olfactory dysfunction was high in both middle aged (86%) and old (78%) participants. Performance on neuropsychological tests showed that persons unaware of their olfactory dysfunction performed poorer on tests of verbal learning and memory and attention/processing speed compared to individuals aware of a normal olfactory status as well as individuals aware of their olfactory dysfunction. The clinical relevance of unawareness of olfactory dysfunction, as suggested earlier, needs further investigation and stresses the need of an extensive multi-modal and longitudinal assessment of unawareness of sensory and cognitive function to learn more about the facets of the concept of unawareness.
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| 3. |
- Rahiminejad, Sofia, 1987, et al.
(författare)
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Micromachined Ridge Gap Waveguide and Resonator for Millimeter-Wave Applications
- 2012
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Ingår i: Sensors and Actuators, A: Physical. - : Elsevier BV. - 0924-4247 .- 1873-3069. ; 186, s. 264-269
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Tidskriftsartikel (refereegranskat)abstract
- The ridge gap waveguide is a fundamentally new high-frequency waveguide. It does not need any electrical contact between the split blocks which gives it an advantage compared to the rectangular waveguide which is the standard today. These waveguides are conventionally fabricated by milling, although above 100 GHz milling is not adequate anymore. MEMS technology on the other hand, can offer high-precision fabrication and thus opens the path for new types of high-frequency components. In this paper both a ridge gap waveguide and a ridge gap resonator have been fabricated for the frequencies 220–325 GHz using MEMS technology. Support packages have been designed to enable device measurements. Simulations show that the reflection coefficient for the ridge gap waveguide is below −15 dB between 240 and 340 GHz. Two resonance peaks were measured at the frequencies 234 GHz and 284 GHz for the ridge gap resonator with unloaded Q-values of 336 and 527 respectively. Both the waveguide and resonator have the potential to obtain similar performances as the rectangular waveguide without strict requirement on electrical contact, allowing simplified fabrication and assembly technique.
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