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Träfflista för sökning "L773:0903 4641 OR L773:1600 0463 srt2:(1995-1999)"

Sökning: L773:0903 4641 OR L773:1600 0463 > (1995-1999)

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  • Hogevik, Harriet, et al. (författare)
  • Virulence factors of Staphylococcus aureus strains causing infective endocarditis--a comparison with strains from skin infections.
  • 1998
  • Ingår i: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. - : Wiley. - 0903-4641 .- 0903-465X .- 1600-5503 .- 1600-0463. ; 106:9, s. 901-8
  • Tidskriftsartikel (refereegranskat)abstract
    • The objective was to study potential bacterial virulence factors in S. aureus endocarditis. S. aureus strains isolated from patients with well-classified episodes of infective endocarditis (IE) (n=26) were compared with control S. aureus strains from consecutive patients with skin infections (n=30). The potential virulence factors studied were Staphylococcal enterotoxin A-D (SEA, SEB, SEC, SED) and toxic shock syndrome toxin-1 (TSST-1) production and binding capacity to the extracellular matrix proteins: fibronectin, collagen type I, collagen type II and bone sialoprotein (BSP). None of the potential virulence factors studied was more prevalent among the IE strains. BSP binding was more often found in the control group with skin infections. Endocarditis patients with previous damage of the heart valves were more often infected by strains not producing any enterotoxin. No correlation was found between the potential bacterial virulence factors studied and IE. Concerning the toxins known to act as superantigens (SEA-E and TSST-1), the tendencies in this and other studies indicate that a larger study group might identify them as pathogenic factors in a subgroup of staphylococcal endocarditis.
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  • Stenram, Unne, et al. (författare)
  • Immunohistochemical expression of metallothionein in resected hepatic primary tumors and colorectal carcinoma metastases
  • 1999
  • Ingår i: APMIS. - : Wiley. - 0903-4641 .- 1600-0463. ; 107:4, s. 420-424
  • Tidskriftsartikel (refereegranskat)abstract
    • Metallothionein is a protein with affinity for metals and is present in several tumors. We examined its immunohistochemical expression in 37 resected primary liver tumors and 117 colorectal metastases. The reaction was intense in the two fibrolamellar hepatocellular carcinomas and in many of the hepatocytes of the pseudotumor case of focal nodular hyperplasia. The reaction was low or moderate in 5 of 17 ordinary hepatocellular carcinomas and in 4 of 14 cholangiocellular carcinomas. There was no reaction in one case each of spindle cell hepatocellular carcinoma, oncocytic adenoma and hemangioendothelial sarcoma. In the metastases, the reaction was low or moderate in 14 cases and negative in 103. Surrounding hepatocytes and stromal cells were more or less positive in all cases.
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  • Resultat 1-10 av 61

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