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- Grondal, L, et al.
(författare)
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Arthrodesis compared to Mayo resection of the first metatarsophalangeal joint in total rheumatoid forefoot reconstruction
- 2005
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Ingår i: Foot & ankle international. - : SAGE Publications. - 1071-1007 .- 1944-7876. ; 26:2, s. 135-139
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Tidskriftsartikel (refereegranskat)abstract
- Background: Painful forefoot deformity from rheumatoid arthritis can be treated with resection of the lesser metatarsal heads combined with either resection or arthrodesis of the first metatarsophalangeal (MTP) joint. Methods: In a prospective, randomized study we compared arthrodesis of first MTP joint with Mayo resection as part of total forefoot reconstruction in patients with painful forefoot deformity from rheumatoid arthritis. The lesser metatarsal heads were resected and extensor tenotomy was done in all patients. Thirty-one patients were randomized to either the arthrodesis or resection group. Results: After a mean followup of 36 (26 to 52) months, the median subjective satisfaction score was 96 points out of 100 in the resection group and 92 points in the arthrodesis group. Significant improvements in pain, handicap, and activity according to Foot Function Index (FFI) were found in both groups ( p < 0.001 except for handicap in resection group and activity in fusion group were p = 0.02). There were no statistically significant differences between the groups in these measures, nor in the patients' willingness to have the procedure again. There were no recurrences of prominences or tenderness under the forefoot in either group and no recurrence of severe hallux valgus in the resection group. The arthrodeses healed in 93%. There was no higher risk for clinically relevant IP joint symptoms after arthrodesis. The operating time was significantly longer in the arthrodesis group but this was not linked to a higher wound infection rate. Conclusion: These results indicate that Mayo resection may still be a good choice for the first MTP joint in total forefoot reconstruction in patients with rheumatoid arthritis.
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- Pfenninger, Cosima, et al.
(författare)
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Tracheal remodeling: comparison of different composite cultures consisting of human respiratory epithelial cells and human chondrocytes
- 2007
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Ingår i: In Vitro Cellular & Developmental Biology - Animal. - : Springer Science and Business Media LLC. - 1071-2690 .- 1543-706X. ; 43:1, s. 28-36
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Tidskriftsartikel (refereegranskat)abstract
- The reconstruction of extensive tracheal defects is still an unsolved challenge for thoracic surgery. Tissue engineering is a promising possibility to solve this problem through the generation of an autologous tracheal replacement from patients' own tissue. Therefore, this study investigated the potential of three different coculture systems, combining human respiratory epithelial cells and human chondrocytes. The coculture systems were analyzed by histological staining with alcian blue, immunohistochemical staining with the antibodies, 34betaE12 and CD44v6, and scanning electron microscopy. The first composite culture consisted of human respiratory epithelial cells seeded on human high-density chondrocyte pellets. For the second system, we used native articular cartilage chips as base for the respiratory epithelial cells. The third system consisted of a collagen membrane, seeded with respiratory epithelial cells and human chondrocytes onto different sides of the membrane, which achieved the most promising results. In combination with an air-liquid interface system and fibroblast-conditioned medium, an extended epithelial multilayer with differentiated epithelial cells could be generated. Our results suggest that at least three factors are necessary for the development towards a tracheal replacement: (1) a basal lamina equivalent, consisting of collagen fibers for cell-cell interaction and cell polarization, (2) extracellular factors of mesenchymal fibroblasts, and (3) the presence of an air-liquid interface system for proliferation and differentiation of the epithelial cells.
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| 8. |
- Khrennikov, Andrei
(författare)
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Einstein-Podolsky-Rosen paradox, Bell's inequality, and the projection postulate
- 2008
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Ingår i: Journal of Russian Laser Research. - : Springer Science and Business Media LLC. - 1071-2836 .- 1573-8760. ; 29:2, s. 101-113
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Tidskriftsartikel (refereegranskat)abstract
- Our aim is to understand the role of implicit assumptions which has been used by Einstein, Podolsky, and Rosen (EPR) in their famous article [Phys. Rev., 47, 777 (1935)] devoted to the so-called EPR paradox. We found that the projection postulate plays a crucial role in the EPR argument. It seems that EPR made a mistake in this paper — the projection postulate was applied not in its original form (as it has been formulated in von Neumann's book [Mathematical Foundations of Quantum mechanics, Princeton University Press (1955)] but in the form which was later formalized as Lüders' postulate [Ann. Phys., Lpz. 8, 322 (1951)]. Von Neumann's postulate was crucially modified by extending it to observables with degenerate spectra. This modification is the real source of “quantum nonlocality.” The use of the original von Neumann postulate eliminates this problem — instead of (an action at a distance)-nonlocality, we obtain a classical measurement nonlocality, which is related to the synchronization of two measurements (produced on the two parts of a composite system). If one uses correctly von Neumann's projection postulate, no “elements of reality” can be assigned to entangled systems.
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| 9. |
- Fang, Yuntuan, et al.
(författare)
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ENHANCEMENT OF THE DEFECT FIELD OF ONE-DIMENSIONAL PHOTONIC CRYSTALS CONTAINING epsilon- AND mu-NEGATIVE LAYERS
- 2008
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Ingår i: Journal of Russian Laser Research. - : Springer Science and Business Media LLC. - 1071-2836 .- 1573-8760. ; 29:5, s. 460-465
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Tidskriftsartikel (refereegranskat)abstract
- Employing the transfer matrix method, we study the electromagnetic field of one-dimensional photonic crystals with a defect inserted by pairs of mu-negative (MNG) and epsilon-negative (ENG) material layers. The fields within the pairs of layers and the matrix defect are independent of each other, and the whole field is their superposition. The whole defect field can be significantly enhanced by pairs of epsilon-negative and mu-negative layers. In contrast to the conventional defect modes, the intensity and volume of the defect field with pairs of epsilon-negative and mu-negative layers can be precisely adjusted.
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