| 1. |
- Chrcanovic, Bruno, et al.
(författare)
-
Dental Implants in Patients Receiving Chemotherapy : A Meta-Analysis
- 2016
-
Ingår i: Implant Dentistry. - : Lippincott Williams & Wilkins. - 1056-6163 .- 1538-2982. ; 25:2, s. 261-271
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose: To test the null hypothesis of no difference in the implant failure rates, postoperative infection, and marginal bone loss for patients being rehabilitated by dental implants and being versus not being submitted to chemotherapy, against the alternative hypothesis of a difference. Methods: An electronic search without time or language restrictions was undertaken in May 2014 in PubMed/MEDLINE, Web of Science, Cochrane Oral Health Group Trials Register plus hand-searching. Eligibility criteria included clinical human studies, either randomized or not. Results: Nine publications were included. The results suggested that the insertion of dental implants in patients submitted or not submitted to chemotherapy did not affect the implant failure rates (risk ratio 1.02, 95% confidence interval 0.56-1.85; P = 0.95). Because of lack of enough information, meta-analyses for the outcomes "postoperative infection" and "marginal bone loss" were not performed. Conclusion: These results cannot suggest that the insertion of dental implants in patients submitted to chemotherapy may or may not affect the implant failure rates, because of a limited number of published studies, most of them characterized by a low level of specificity and dealing with a limited number of cases without a control group. The reliability and validity of the data collected and the potential for biases and confounding factors are some of the shortcomings of the present study.
|
|
| 2. |
- Coelho, Paulo G., et al.
(författare)
-
Enhanced Bone Bonding to Nanotextured Implant Surfaces at a Short Healing Period : A Biomechanical Tensile Testing in the Rat Femur
- 2016
-
Ingår i: Implant Dentistry. - : Lippincott Williams & Wilkins. - 1056-6163 .- 1538-2982. ; 25:3, s. 322-327
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose: To compare the bone bonding capabilities of 2 different surface treatments at an early healing period. Titanium alloy (Ti6Al4V) custom-made rectangular plates (1.4 x 2.4 x 4 mm) were either dual acid etched (Ti6Al4V-DAE) or nanotextured proprietary processed Ti6Al4V-Ossean (intraLock International, Boca Raton, FL). Materials and Methods: Implants were placed in the distal femurs of 10 Wistar rats and were allowed to heal for 9 days. After euthanasia, the bone immediately proximal and distal to the implant was removed to test the bone bonding force with a universal testing machine. Ultrastructure of the bone/implant interface was assessed by scanning electron microscopy Results: Ti6Al4V-NTB samples exhibited significantly greater bond strength than Ti6Al4V-DAE samples. Morphologically, the Ti6Al4V-Ossean surfaces presented intimate interaction with bone, whereas little interaction between the Ti6Al4V-DAE surface and bone was observed Conclusion: The results of this study indicated a significant increase in bone bonding for the Ossean surface, which is suggested to be the outcome of the nanotexturing.
|
|
| 3. |
- Jimbo, Ryo, et al.
(författare)
-
Alignment of Biological Apatite c-Axis Under Functional Loading : A Preliminary Report
- 2016
-
Ingår i: Implant Dentistry. - : Lippincott Williams & Wilkins. - 1056-6163 .- 1538-2982. ; 25:5, s. 594-598
-
Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To understand the bone modeling/remodeling process of functionally loaded implants by observing the alignment of the biological apatite (BAp) c-axis. MATERIALS AND METHODS: Commercially available titanium implants with TiO2 grit-blasted surfaces were placed in the fourth premolar and the first molar of the beagle dog and were functionally loaded with casted crowns and were compared to the non-loaded controls. After being killed, the samples were subjected to histological observation and to a microbeam x-ray diffraction (μXRD) analysis with a transmission optical system to evaluate the preferential BAp c-axis alignment. RESULTS: The non-loaded group presented mostly nonoriented BAp c-axis around the implant, whereas for the loaded group, preferential alignment of BAp c-axis was observed along the loading direction of the implant suggesting that the Bap aligned itself based on the direction of the functional mechanical loading. CONCLUSION: The μXRD revealed that the c-axis orientation was perpendicular to the implant thread working against the functional loaded direction, which may contribute in designing an optimal implant macrogeometry.
|
|
| 4. |
- Shimizu, Hideo, et al.
(författare)
-
Tissue Reaction to a Novel Bone Substitute Material Fabricated With Biodegradable Polymer-Calcium Phosphate Nanoparticle Composite
- 2016
-
Ingår i: Implant Dentistry. - : Lippincott Williams & Wilkins. - 1056-6163 .- 1538-2982. ; 25:5, s. 567-574
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose: The aim of this study was to evaluate the effectiveness of a novel bone substitute material fabricated using a biodegradable polymer-calcium phosphate nanoparticle composite. Methods: Porous structured poly-L-lactic acid (PLLA) and hydroxyapatite (HA) nanoparticle composite, which was fabricated using solid-liquid phase separation and freeze-drying methods, was grafted into bone defects created in rat calvarium or tibia. Rats were killed 4 weeks after surgery, and histological analyses were performed to evaluate new bone formation. Results: Scanning electron microscopic observation showed the interconnecting pores within the material and the pore diameter was approximately 100 to 300 mm. HA nanoparticles were observed to be embedded into the PLLA beams. In the calvarial implantation model, abundant blood vessels and fibroblastic cells were observed penetrating into pores, and in the tibia model, newly formed bone was present around and within the composite. Conclusions: The PLLA-HA nanoparticle composite bone substitute developed in this study showed biocompatibility, elasticity, and operability and thus has potential as a novel bone substitute.
|
|
| 5. |
- Takeshita, Kenji, et al.
(författare)
-
Implant Vertical Fractures Provoked by Laboratory Procedures : A Finite Element Analysis Inspired from Clinical Cases
- 2016
-
Ingår i: Implant Dentistry. - : Lippincott Williams & Wilkins. - 1056-6163 .- 1538-2982. ; 25:3, s. 361-366
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose: To investigate the causes for internal implant fractures, which is suggested to be one of the reasons for marginal bone loss. Materials and Methods: From a 14-year database of 6051 implants, 10 single implant vertical fractures were identified and the abutments were all castable abutments. The abutments presented contamination and irregularities at the internal connecting areas. The hypothesis was that perfect fit was disturbed by laboratory polishing procedures, and finite element analysis (FEA) using overcorrected and undercorrected castable abutment models were created and tested against a perfect fit model Results: The results from the FEA presented that both overcorrected and undercorrected models presented nonuniform excessive plastic strain distribution in the neck portion of the implants where clinically an implant fracture was noted Conclusions: The results suggested that laboratory procedures could induce plastic strain of the implant-abutment complex, which increases the risk of fracture
|
|
