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Träfflista för sökning "L773:1754 6605 srt2:(2015-2019)"

Sökning: L773:1754 6605 > (2015-2019)

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1.
  • Crawley, Danielle, et al. (författare)
  • A systematic review of the literature exploring the interplay between prostate cancer and type two diabetes mellitus
  • 2018
  • Ingår i: ecancermedicalscience. - : Ecancer Global Foundation. - 1754-6605. ; 12
  • Forskningsöversikt (refereegranskat)abstract
    • Prostate cancer (PCa) and type two diabetes mellitus (T2DM) are both increasing prevalent conditions and often occur concurrently. However, the relationship between the two is more complex than just two prevalent conditions co-existing. This review systematically explores the literature around the interplay between the two conditions. It covers the impact of pre-existing T2DM on PCa incidence, grade and stage, as well as exploring the impact of T2DM on PCa outcomes and mortality and the interaction between T2DM and PCa treatments.
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2.
  • Ghoshal, Arunangshu, et al. (författare)
  • Serum biomarkers to predict risk of testicular and penile cancer in AMORIS
  • 2017
  • Ingår i: ecancermedicalscience. - : CANCER INTELLIGENCE LTD. - 1754-6605. ; 11
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: To evaluate the association between commonly measured serum biomarkers of inflammation and penile and testicular cancer risk in the Swedish Apolipoprotein-related MORtality RISk (AMORIS) study.Materials and methods: A total of 205,717 subjects had baseline measurements of C-reactive protein, albumin, and haptoglobin. The association between quartiles and dichotomised values of inflammatory markers and penile and testicular cancer risk were analysed by using multivariate Cox proportional hazard models.Results: A total of 125 men were diagnosed with testicular cancer and 50 with penile cancer during a mean follow-up of 20.3 years. No statistically significant trends were seen between serum inflammatory markers and risk of penile cancer, but higher albumin levels increased the risk of testicular cancer [HR for albumin (g/L): 1.10 (95% CI: 1.03-1.18)]. However, this trend was not observed when using medical cut-offs of albumin.Conclusions: In the present study, we did not find support for an association between commonly used markers of inflammation and risk of testicular or penile cancer. The role of inflammation may be more complicated and require assessment of more specialised measurements of inflammation in future studies.
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