| 1. |
- Jonsson, BH, et al.
(författare)
-
What is hidden in tattoos?
- 2015
-
Ingår i: American journal of clinical pathology. - : Oxford University Press (OUP). - 1943-7722 .- 0002-9173. ; 143:6, s. 908-909
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Porwit, A, et al.
(författare)
-
Acute leukemias of ambiguous origin
- 2015
-
Ingår i: American journal of clinical pathology. - 1943-7722. ; 144:3, s. 361-376
-
Tidskriftsartikel (refereegranskat)
|
|
| 5. |
- Rusanganwa, Vincent, 1966-, et al.
(författare)
-
Clinical Referral Laboratories in Rwanda : The Status of Quality Improvement After 7 Years of the SLMTA Program
- 2018
-
Ingår i: American Journal of Clinical Pathology. - : Oxford University Press. - 0002-9173 .- 1943-7722. ; 150:3, s. 240-245
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives: We investigated the quality system performance in Rwandan referral laboratories to determine their progress toward accreditation.Methods: We conducted audits across five laboratories in 2017, using the Stepwise Laboratory Quality Improvement Process Towards Accreditation checklist. Laboratories were scored based on the World Health Organization grading scale (0-5 stars scale) and compared with earlier audits.Results: Between 2012 and 2017, only one laboratory progressed (from four to five stars). Four of the five laboratories decreased to one (three laboratories) and zero (one laboratory) stars from four and three stars. Management reviews, evaluation, audits, documents, records, and identification of nonconformities showed a low performance.Conclusions: Four of five laboratories are not moving toward accreditation. However, this target is still achievable by energizing responsibilities of stakeholders and monitoring and evaluation. This would be possible because of the ability that laboratories showed in earlier audits, coupled with existing health policy that enables sustainable quality health care in Rwanda.
|
|
| 6. |
- Rusanganwa, Vincent, et al.
(författare)
-
Clinical Referral Laboratory Personnel’s Perception of Challenges and Strategies for Sustaining the Laboratory Quality Management System : A Qualitative Study in Rwanda
- 2019
-
Ingår i: American Journal of Clinical Pathology. - : Oxford University Press (OUP). - 0002-9173 .- 1943-7722. ; 152:6, s. 725-734
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives: To explore challenges explaining the decrease in quality performance and suggest strategies to improve and sustain laboratory quality services.Methods: Twenty key informants’ interviews from laboratory personnel were conducted in five laboratories. Four had previously shown a decrease in quality performance. Interviews were transcribed verbatim and analyzed using inductive thematic analysis.Results: Two themes emerged: (1) insufficient coordination and follow-up system towards accreditation, where lack of coordination, follow-up, and audits explained the decrease in performance; (2) inadequate resource optimization, where insufficient knowledge in Laboratory Quality Management System (LQMS), ownership by laboratory workforce, and insufficient stakeholders’ communication contributed to low-quality performance.Conclusions: The coordination, follow-up, and assessments of LQMS, in conjunction with training of laboratory workforce, would establish an institutional culture of continuous quality improvement (CQI) towards accreditation and sustainment of quality health care. To achieve CQI culture, routine gap checking and planning for improvement using a system approach is required.
|
|
| 7. |
- Strosberg, C., et al.
(författare)
-
Update on Neuroendocrine Carcinomas of the Larynx
- 2019
-
Ingår i: American Journal of Clinical Pathology. - : Oxford University Press (OUP). - 0002-9173 .- 1943-7722. ; 152:6, s. 686-700
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives: Laryngeal neuroendocrine carcinomas are heterogeneous neoplasms characterized by neuroendocrine differentiation. Their prognoses are dependent on tumor type, therefore different classifications have been developed. Moreover, other tumors have overlapping pathologic features posing a range of diagnostic possibilities. Methods: A review of the literature was performed to comprehensively understand the classification and diagnosis of these tumors. Results: We review the past and present classification systems, with emphasis to the latest 2017 World Health Organization Classification of Head and Neck Tumors. We highlight salient clinicopathologic features and discuss the presumptive etiologic role of human papilloma virus. We share a practical algorithmic approach to the diagnosis of suspected neuroendocrine neoplasms of the larynx including a novel marker for neuroendocrine differentiation, insulinoma-associated protein 1. Conclusions: Accurate diagnosis and grading of laryngeal neuroendocrine carcinomas is critical for prognostication and therapeutic decision making. The use of an algorithm is instrumental in assuring the exclusion of mimickers.
|
|
| 8. |
- Vidarsdottir, Halla, et al.
(författare)
-
Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastase
- 2018
-
Ingår i: American Journal of Clinical Pathology. - : Oxford University Press (OUP). - 0002-9173 .- 1943-7722. ; 150:6, s. 533-544
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives: Immunohistochemical staining against thyroid transcription factor 1 (TTF-1) is often used to distinguish lung adenocarcinoma from squamous cell carcinoma and pulmonary metastasis.Methods: TTF-1 expression was examined using the antibody clones 8G7G3/1, SPT24, and SP141 on tissue microarrays from 665 cases of resected lung cancers and 428 pulmonary metastases.Results: Most lung adenocarcinomas, 89%, 93%, and 93%, were positive with TTF-1 clones 8G7G3/1, SPT24, and SP141, respectively. The corresponding figures for lung squamous cell carcinomas were 0%, 6%, and 8%. In total, five (2%), 19 (7%), and 21 (8%) of the pulmonary metastases from colorectal adenocarcinomas were positive with clones 8G7G3/1, SPT24, and SP141, respectively. Other TTF-1-positive pulmonary metastases (n = 8) were thyroid, urothelial, pancreatic, small bowel, and cervix carcinomas.Conclusions: TTF-1 expression in lung cancer and pulmonary metastases differs between clones, with 8G7G3/1 being more specific but less sensitive compared with SPT24 and SP141.
|
|
