| 1. |
- Malmgren, Linnea, et al.
(författare)
-
The complexity of kidney disease and diagnosing it - Cystatin C, selective glomerular hypofiltration syndromes and proteome regulation.
- 2023
-
Ingår i: Journal of Internal Medicine. - : John Wiley & Sons. - 0954-6820 .- 1365-2796. ; 293:3, s. 293-308
-
Tidskriftsartikel (refereegranskat)abstract
- Estimation of kidney function is often part of daily clinical practice, mostly done by using the endogenous GFR-markers creatinine or cystatin C. A recommendation to use both markers in parallel in 2010 has resulted in new knowledge concerning the pathophysiology of kidney disorders by identification of a new set of kidney disorders, selective glomerular hypofiltration syndromes. These syndromes, connected to strong increases in mortality and morbidity, are characterised by a selective reduction in the glomerular filtration of 5-30 kDa molecules, such as cystatin C, compared to the filtration of small molecules < 1kDa dominating the glomerular filtrate e.g., water, urea, creatinine. At least two types of such disorders, shrunken or elongated pore syndrome, are possible according to the pore model for glomerular filtration. Selective glomerular hypofiltration syndromes are prevalent in investigated populations, and patients with these syndromes often display normal measured GFR or creatinine-based GFR-estimates. The syndromes are characterised by proteomic changes promoting the development of atherosclerosis, indicating antibodies and specific receptor-blocking substances as possible new treatment modalities. Presently, the KDIGO guidelines for diagnosing kidney disorders do not recommend cystatin C as a general marker of kidney function and will therefore not allow the identification of a considerable number of patients with selective glomerular hypofiltration syndromes. Furthermore, as cystatin C is uninfluenced by muscle mass, diet or variations in tubular secretion and cystatin C-based GFR-estimation equations do not require controversial race or sex terms, it is obvious that cystatin C should be a part of future KDIGO guidelines.
|
|
| 2. |
- Ahlbäck Öberg, Shirin, Professor, 1964-, et al.
(författare)
-
Avkollegialiseringen av svenska lärosäten : En analys av statliga universitet och högskolor
- 2022
-
Ingår i: Statsvetenskaplig Tidskrift. - Lund : Fahlbeckska stiftelsen. - 0039-0747. ; 124:1, s. 157-209
-
Tidskriftsartikel (refereegranskat)abstract
- The Decollegialization of Higher Education Institutions – an Examination of Public Sector Higher Education Institutions in SwedenThis article surveys current management ideals of higher education institutions (HEIs), and our analytical focus is on the balance between line management and fac-ulty self-governance. We present an empirical study of evolving governance struc-tures including all 31 public sector HEIs in Sweden. The point of departure is the Autonomy Reform of 2011, which resulted in a deregulation of the Higher Education Act and a loss of constitutional support for collegial bodies. To assess the conse-quences of the reform, we have examined collegial bodies and academic leadership posts before and after the reform. Our findings show escalating line management in the appointment of academic leaders, a diluted role for collegial expertise, and a loss of decision-making authority for collegial bodies. Hence, the decollegialization of HEIs in Sweden. Our study contributes to the existing literature with an unusually comprehensive analysis of the consequences of new managerial ideals at the local institutional level.
|
|
| 3. |
- Ahlbäck Öberg, Shirin, Professor, 1964-, et al.
(författare)
-
Svenska lärosäten : organisering, finansiering, positionering
- 2022
-
Ingår i: Statsvetenskaplig Tidskrift. - Lund : Fahlbeckska stiftelsen. - 0039-0747. ; 124:1, s. 5-18
-
Tidskriftsartikel (refereegranskat)abstract
- Våren 2021 tog riksdagen ställning till den elfte forskningspolitiska propositionen i ordningen, Forskning, frihet, framtid – kunskap och innovation för Sverige (prop. 2020/21:60). Bara genom att studera forskningspropositionernas rubriker kan man enkelt avläsa vilka primära mål sittande regering har med sin forskningspolitik. Förra gången det begav sig stod samverkan högst på agendan. På propositionens 167 sidor nämndes ”samverkan” hela 224 gånger, medan en konkurrent som ”frihet” i stort lyste med sin frånvaro och enbart nämndes sex gånger (prop. 2016/17:50). I den nu aktuella forskningspropositionen har emellertid ”frihet” getts en mer framträdande roll än någonsin tidigare – vilket även framgår av rubriken – och omnämns hela 141 gånger (”samverkan” är dock mer än dubbelt så vanligt) (prop. 2020/21:60). Skälet till att frihetsfrågan fått en så framträdande roll denna gång är förstås de förslag om att föra in akademisk frihet i högskolelagen som Styr- och resursutredningen presenterat i sitt betänkande (”Struten”, se SOU 2019:6). Men hur ska vi förstå denna politiska strävan efter att stärka den akademiska friheten? I detta specialnummer tar vi ett bredare grepp om hur högskolepolitiken utvecklats över tid, och frågar oss vad som utmärker denna frihet. Vem är det som ska ges frihet? Hur ser balansen mellan formell och reell frihet ut? Vad utmärker dem som skänks frihet – oftast lärosätena – och hur skiljer de sig åt?
|
|
| 4. |
- Ahlbäck Öberg, Shirin, Professor, 1964-, et al.
(författare)
-
The Decollegialization of Higher Education Institutions in Sweden
- 2023
-
Ingår i: Nordic Journal of Studies in Educational Policy. - : Routledge. - 2002-0317. ; 9:2, s. 126-143
-
Tidskriftsartikel (refereegranskat)abstract
- This article surveys current management ideals of higher education institutions, and our analytical focus is on the balance between line management and faculty self-governance. It presents an empirical study of evolving governance structures including all 31 public sector higher education institutions in Sweden. The point of departure is the Autonomy Reform of 2011, which resulted in a deregulation of the Higher Education Act, and a loss of constitutional support for collegial bodies. To assess the consequences of the reform, we have examined collegial bodies and academic leadership posts before the reform (2010) and after (2020). Our findings show escalating line management in the appointment of academic leaders, a diluted role for collegial expertise, and a loss of decision-making authority for collegial bodies. What we observe is the decollegialization of higher education institutions. Our study contributes to the existing literature with an unusually comprehensive and fine-grained analysis of the consequences of new managerial ideals at the local institutional level.
|
|
| 5. |
- Ahlbäck Öberg, Shirin, Professor, 1964-, et al.
(författare)
-
Ökad kontroll och ökad byråkratisering : En kartläggning av statens styrning av universitet och högskolor
- 2024
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- I denna rapport kartlägger vi den ökade kontrollen och ökade byråkratiseringen av framförallt de statliga lärosätena i Sverige under åren 1993–2023. Vi har analyserat utvecklingen av högskoleförfattningarna, regleringsbreven riktade mot universitet och högskolor (gemensamma och individuella) och relevanta sektorsmyndigheters, samt de generella författningar som träffar lärosätena antingen i egenskap av statliga myndigheter eller genom en mer generell räckvidd även bortom myndigheterna.Vår undersökning visar att det framförallt är generell lagstiftning kopplad till olika politiska målsättningar – tillsammans med staplandet av politiska mål i högskoleförfattningarna – som sammantaget resulterar i en orimlig administrativ börda för lärosätena. Den målträngsel som vi åskådliggör vittnar om en oförmåga hos lagstiftaren att prioritera. Även om en del av den generella lagstiftningen i någon mån varit aktuell redan vid undersökningsperiodens början så har den politiska ambitionsnivån på de flesta områden höjts avsevärt under senare år. Ytterst sällan åtföljs de stegrade ambitionerna av tillförda resurser, utan de nya eller ”förtydligade” uppgifterna ska istället i nästan samtliga fall utföras inom befintliga ekonomiska ramar. Vi menar att det är anmärkningsvärt att fler och fler byråkratidrivande regelverk införs utan att man vid något tillfälle diskuterar hur detta kommer att påverka lärosätenas möjligheter att bedriva kärnverksamheten.
|
|
| 6. |
- Aramo-Immonen, Heli, 1964-, et al.
(författare)
-
Charting the reach and contribution of IMP literature in other disciplines : A bibliometric analysis
- 2020
-
Ingår i: Industrial Marketing Management. - : Elsevier. - 0019-8501 .- 1873-2062. ; 87, s. 47-62
-
Tidskriftsartikel (refereegranskat)abstract
- The acknowledgement of a research tradition by other disciplines shows its contribution to the development of the broader body of scientific knowledge. This paper investigates the contribution of IMP (Industrial Marketing and Purchasing) research to broader research disciplines by analyzing how researchers within and beyond IMP have cited core IMP articles. First, through quantitative bibliometric analysis, the paper identifies the diffusion to other research disciplines. Thereafter, through qualitative analysis, the impact of the IMP perspective is captured to understand how strong these imprints are. The analyses show that IMP research has been noticed among a range of adjacent research disciplines. However, the use of IMP references has generally been rudimentary, and without a deeper understanding of the IMP ontology, meaning that IMP still has some “weak ties” to the other disciplines. Establishing IMP's contribution through enduring imprints would need further engagement with researchers from other research disciplines and publications in top journals. The paper contributes empirically with how the IMP perspective has spread beyond the IMP Group and theoretically by adding insight into how research ideas travel and transform to other disciplines.
|
|
| 7. |
|
|
| 8. |
- Lagin, Madelen, 1982-, et al.
(författare)
-
Last-mile logistics of perishable products : a review of effectiveness and efficiency measures used in empirical research
- 2022
-
Ingår i: International Journal of Retail & Distribution Management. - : Emerald Group Publishing Limited. - 0959-0552 .- 1758-6690. ; 50:13, s. 116-139
-
Tidskriftsartikel (refereegranskat)abstract
- PurposeCurrent online business development redistributes last-mile logistics (LML) from consumer to retailer and producer. This paper identifies how empirical LML research has used and defined logistic performance measures for key grocery industry actors. Using a multi-actor perspective on logistic performance, the authors discuss coordination issues important for optimising LML at system level.Design/methodology/approachA semi-systematic literature review of 85 publications was conducted to analyse performance measurements used for effectiveness and efficiency, and for which actors.FindingsFew empirical LML studies exist examining coordination between key actors or on system level. Most studies focus on logistic performance measurements for retailers and/or consumers, not producers. Key goals and resource utilisations lack research, including all key actors and system-level coordination.Research limitations/implicationsCurrent LML performance research implies a risk for sub-optimisation. Through expanding on efficiency and effectiveness interplay at system level and introducing new research perspectives, the review highlights the need to revaluate single-actor, single-measurement studies.Practical implicationsNo established scientific guidelines exist for solving LML optimisation in the grocery industry. For managers, it is important to thoroughly consider efficiency and effectiveness in LML execution, coordination and collaboration among key actors, avoiding sub-optimisations for business and sustainability.Originality/valueThe study contributes to current knowledge by reviewing empirical research on LML performance in the grocery sector, showing how previous research disregards the importance of multiple actors and coordination of actors, efficiency and effectiveness.
|
|
| 9. |
- Lagin, Madelen, et al.
(författare)
-
Last-mile logistics of perishable products : A review of effectiveness and efficiency measures used in empirical research
- 2022
-
Ingår i: International Journal of Retail & Distribution Management. - : Emerald Group Publishing Limited. - 0959-0552 .- 1758-6690. ; 50:13, s. 116-139
-
Forskningsöversikt (refereegranskat)abstract
- Purpose Current online business development redistributes last-mile logistics (LML) from consumer to retailer and producer. This paper identifies how empirical LML research has used and defined logistic performance measures for key grocery industry actors. Using a multi-actor perspective on logistic performance, the authors discuss coordination issues important for optimising LML at system level. Design/methodology/approach A semi-systematic literature review of 85 publications was conducted to analyse performance measurements used for effectiveness and efficiency, and for which actors. Findings Few empirical LML studies exist examining coordination between key actors or on system level. Most studies focus on logistic performance measurements for retailers and/or consumers, not producers. Key goals and resource utilisations lack research, including all key actors and system-level coordination. Research limitations/implications Current LML performance research implies a risk for sub-optimisation. Through expanding on efficiency and effectiveness interplay at system level and introducing new research perspectives, the review highlights the need to revaluate single-actor, single-measurement studies. Practical implications No established scientific guidelines exist for solving LML optimisation in the grocery industry. For managers, it is important to thoroughly consider efficiency and effectiveness in LML execution, coordination and collaboration among key actors, avoiding sub-optimisations for business and sustainability. Originality/value The study contributes to current knowledge by reviewing empirical research on LML performance in the grocery sector, showing how previous research disregards the importance of multiple actors and coordination of actors, efficiency and effectiveness.
|
|
| 10. |
- Liénart, Camilla, et al.
(författare)
-
Long‐term changes in trophic ecology of blue mussels in a rapidly changing ecosystem
- 2021
-
Ingår i: Limnology and Oceanography. - : Wiley. - 0024-3590 .- 1939-5590. ; 66:3, s. 694-710
-
Tidskriftsartikel (refereegranskat)abstract
- Ocean climate change strongly affects organisms and ecosystems, and the causes, consequences, and underlying mechanisms need to be documented. In the Baltic Sea, a marginal sea under severe eutrophication stress, a longer productive season, and changes in the phytoplankton community over the last few decades have likely impacted diet and condition of keystone species, from individual to population level. This study uses stable isotopes (δ13C, δ15N, and derived isotope niche metrics) to trace energy and nutrient flows in archived samples of blue mussel (Mytilus edulis trossulus) spanning 24 yr (1993–2016). We test if long-term changes in isotope and elemental composition in mussels, as well as population abundance and biomass, can be explained by changes in abiotic and biotic variables, using partial least square regressions and structural equation modeling. We found decreasing trends in δ13C and δ15N as well as in mean size and total biomass of mussels, but no unidirectional changes in their stoichiometry or condition index. Changes in isotope composition were best explained by nitrogen-fixing cyanobacteria, by increased terrestrial organic carbon from land runoff (reflecting precipitation) and by decreases in dissolved inorganic nitrogen (indicative of successful eutrophication mitigation) and in biomass of a mixotrophic ciliate species. The trophic niche (assessed from isotope niche) was included as the best predictor for both mussel body condition and the observed decline in their total biomass. This study reveals that altered trophic relationships from climate-induced changes in the productivity base may strongly impact keystone species, with potential knock-on effects on ecosystem functions.
|
|
